Κυριακή 30 Ιουνίου 2019

IJMS, Vol. 20, Pages 3232: Cardiodynamic Interactions between Two S1P1 Receptor Modulators in an Experimental Clinical Setting: Different Pharmacokinetic Properties as an Opportunity to Mitigate First-Dose Heart Rate Effects
IJMS, Vol. 20, Pages 3232: Cardiodynamic Interactions between Two S1P1 Receptor Modulators in an Experimental Clinical Setting: Different Pharmacokinetic Properties as an Opportunity to Mitigate First-Dose Heart Rate Effects International Journal of Molecular Sciences doi: 10.3390/ijms20133232 Authors: Pierre-Eric Juif Mike Ufer Jasper Dingemanse A decrease in heart rate (HR) is a well-established first-dose effect of sphingosine-1-phosphate subtype 1 receptor (S1P1R) modulators....
International Journal of Molecular Sciences
03:00
IJMS, Vol. 20, Pages 3231: Carcinoembryonic Cell Adhesion-Related Molecule 2 Regulates Insulin Secretion and Energy Balance
IJMS, Vol. 20, Pages 3231: Carcinoembryonic Cell Adhesion-Related Molecule 2 Regulates Insulin Secretion and Energy Balance International Journal of Molecular Sciences doi: 10.3390/ijms20133231 Authors: Elsaid Salaheldeen Alexa Jaume Sonia Michael Najjar The Carcinoembryonic Antigen-Related Cell Adhesion Molecule (CEACAM) family of proteins plays a significant role in regulating peripheral insulin action by participating in the regulation of insulin metabolism and energy balance....
International Journal of Molecular Sciences
03:00
IJMS, Vol. 20, Pages 3229: Maternal and Post-weaning High-Fat Diets Produce Distinct DNA Methylation Patterns in Hepatic Metabolic Pathways within Specific Genomic Contexts
IJMS, Vol. 20, Pages 3229: Maternal and Post-weaning High-Fat Diets Produce Distinct DNA Methylation Patterns in Hepatic Metabolic Pathways within Specific Genomic Contexts International Journal of Molecular Sciences doi: 10.3390/ijms20133229 Authors: Moody Wang Jung Chen Pan Calorie-dense high-fat diets (HF) are associated with detrimental health outcomes, including obesity, cardiovascular disease, and diabetes. Both pre- and post-natal HF diets have been hypothesized...
International Journal of Molecular Sciences
Sun Jun 30, 2019 03:00
IJMS, Vol. 20, Pages 3230: NMR Fragment-Based Screening against Tandem RNA Recognition Motifs of TDP-43
IJMS, Vol. 20, Pages 3230: NMR Fragment-Based Screening against Tandem RNA Recognition Motifs of TDP-43 International Journal of Molecular Sciences doi: 10.3390/ijms20133230 Authors: Gilbert Nshogoza Yaqian Liu Jia Gao Mingqing Liu Sayed Ala Moududee Rongsheng Ma Fudong Li Jiahai Zhang Jihui Wu Yunyu Shi Ke Ruan The TDP-43 is originally a nuclear protein but translocates to the cytoplasm in the pathological condition. TDP-43, as an RNA-binding protein, consists...
International Journal of Molecular Sciences
Sun Jun 30, 2019 03:00
IJMS, Vol. 20, Pages 3227: Chemical Kinetics of Hydrogen Atom Abstraction from Propargyl Sites by Hydrogen and Hydroxy Radicals
IJMS, Vol. 20, Pages 3227: Chemical Kinetics of Hydrogen Atom Abstraction from Propargyl Sites by Hydrogen and Hydroxy Radicals International Journal of Molecular Sciences doi: 10.3390/ijms20133227 Authors: Wang Sun Sun Liang Hydrogen atom abstraction from propargyl C-H sites of alkynes plays a critical role in determining the reactivity of alkyne molecules and understanding the formation of soot precursors. This work reports a systematic theoretical study on the reaction...
International Journal of Molecular Sciences
Sun Jun 30, 2019 03:00
IJMS, Vol. 20, Pages 3228: Adiponectin and Cardiovascular Risk. From Pathophysiology to Clinic: Focus on Children and Adolescents
IJMS, Vol. 20, Pages 3228: Adiponectin and Cardiovascular Risk. From Pathophysiology to Clinic: Focus on Children and Adolescents International Journal of Molecular Sciences doi: 10.3390/ijms20133228 Authors: Antonina Orlando Elisa Nava Marco Giussani Simonetta Genovesi Adiponectin (Ad) is a cytokine produced by adipocytes that acts on specific receptors of several tissues through autocrine, paracrine, and endocrine signaling mechanisms. Ad is involved in the regulation of cell...
International Journal of Molecular Sciences
Sun Jun 30, 2019 03:00
IJMS, Vol. 20, Pages 3226: Diversifying Evolution of the Ubiquitin-26S Proteasome System in Brassicaceae and Poaceae
IJMS, Vol. 20, Pages 3226: Diversifying Evolution of the Ubiquitin-26S Proteasome System in Brassicaceae and Poaceae International Journal of Molecular Sciences doi: 10.3390/ijms20133226 Authors: Hua Yu : Genome amplification and sequence divergence provides raw materials to allow organismal adaptation. This is exemplified by the large expansion of the ubiquitin-26S proteasome system (UPS) in land plants, which primarily rely on intracellular signaling and biochemical metabolism...
International Journal of Molecular Sciences
Sun Jun 30, 2019 03:00
IJMS, Vol. 20, Pages 3224: Heart Failure Differentially Modulates Natural (Sinoatrial Node) and Ectopic (Pulmonary Veins) Pacemakers: Mechanism and Therapeutic Implication for Atrial Fibrillation
IJMS, Vol. 20, Pages 3224: Heart Failure Differentially Modulates Natural (Sinoatrial Node) and Ectopic (Pulmonary Veins) Pacemakers: Mechanism and Therapeutic Implication for Atrial Fibrillation International Journal of Molecular Sciences doi: 10.3390/ijms20133224 Authors: Chao-Shun Chan Yung-Kuo Lin Yao-Chang Chen Yen-Yu Lu Shih-Ann Chen Yi-Jen Chen Heart failure (HF) frequently coexists with atrial fibrillation (AF) and dysfunction of the sinoatrial node (SAN), the...
International Journal of Molecular Sciences
Sun Jun 30, 2019 03:00
IJMS, Vol. 20, Pages 3225: A Stress-Responsive NAC Transcription Factor from Tiger Lily (LlNAC2) Interacts with LlDREB1 and LlZHFD4 and Enhances Various Abiotic Stress Tolerance in Arabidopsis
IJMS, Vol. 20, Pages 3225: A Stress-Responsive NAC Transcription Factor from Tiger Lily (LlNAC2) Interacts with LlDREB1 and LlZHFD4 and Enhances Various Abiotic Stress Tolerance in Arabidopsis International Journal of Molecular Sciences doi: 10.3390/ijms20133225 Authors: Yong Zhang Lyu Our previous studies have indicated that a partial NAC domain protein gene is strongly up-regulated by cold stress (4 °C) in tiger lily (Lilium lancifolium). In this study, we cloned the...
International Journal of Molecular Sciences
Sun Jun 30, 2019 03:00
IJMS, Vol. 20, Pages 3222: IL-13 Impairs Tight Junctions in Airway Epithelia
IJMS, Vol. 20, Pages 3222: IL-13 Impairs Tight Junctions in Airway Epithelia International Journal of Molecular Sciences doi: 10.3390/ijms20133222 Authors: Schmidt Braubach Schilpp Lochbaum Neuland Thompson Jonigk Frick Dietl Wittekindt Interleukin-13 (IL-13) drives symptoms in asthma with high levels of T-helper type 2 cells (Th2-cells). Since tight junctions (TJ) constitute the epithelial diffusion barrier, we investigated the effect of IL-13 on...
International Journal of Molecular Sciences
Sun Jun 30, 2019 03:00
IJMS, Vol. 20, Pages 3221: Influence of ABO Locus on PFA-100 Collagen-ADP Closure Time Is Not Totally Dependent on the Von Willebrand Factor. Results of a GWAS on GAIT-2 Project Phenotypes
IJMS, Vol. 20, Pages 3221: Influence of ABO Locus on PFA-100 Collagen-ADP Closure Time Is Not Totally Dependent on the Von Willebrand Factor. Results of a GWAS on GAIT-2 Project Phenotypes International Journal of Molecular Sciences doi: 10.3390/ijms20133221 Authors: Núria Pujol-Moix Angel Martinez-Perez Maria Sabater-Lleal Dolors Llobet Noèlia Vilalta Anders Hamsten Joan Carles Souto José Manuel Soria (1) Background: In a previous study, we found that two phenotypes...
International Journal of Molecular Sciences
Sun Jun 30, 2019 03:00

IJMS, Vol. 20, Pages 3220: Selective Anticancer Therapy Using Pro-Oxidant Drug-Loaded Chitosan–Fucoidan Nanoparticles
IJMS, Vol. 20, Pages 3220: Selective Anticancer Therapy Using Pro-Oxidant Drug-Loaded Chitosan–Fucoidan Nanoparticles International Journal of Molecular Sciences doi: 10.3390/ijms20133220 Authors: Dae Gun Choi Jayachandran Venkatesan Min Suk Shim Pro-oxidant therapy exploiting pro-oxidant drugs that can trigger cytotoxic oxidative stress in cancer cells has emerged as an innovative strategy for cancer-specific therapy. Piperlongumine (PL) has gained great interest as a novel pro-oxidant...
International Journal of Molecular Sciences
Sun Jun 30, 2019 03:00
IJMS, Vol. 20, Pages 3223: Single Mild Traumatic Brain Injury Induces Persistent Disruption of the Blood-Brain Barrier, Neuroinflammation and Cognitive Decline in Hypertensive Rats
IJMS, Vol. 20, Pages 3223: Single Mild Traumatic Brain Injury Induces Persistent Disruption of the Blood-Brain Barrier, Neuroinflammation and Cognitive Decline in Hypertensive Rats International Journal of Molecular Sciences doi: 10.3390/ijms20133223 Authors: Nikolett Szarka Luca Toth Andras Czigler Zoltan Kellermayer Zoltan Ungvari Krisztina Amrein Endre Czeiter Zsolt Kristof Bali Sai Ambika Tadepalli Matyas Wahr Istvan Hernadi Akos Koller Andras Buki Peter...
International Journal of Molecular Sciences
Sun Jun 30, 2019 03:00
IJMS, Vol. 20, Pages 3218: Trifluoperazine, an Antipsychotic Drug, Effectively Reduces Drug Resistance in Cisplatin-Resistant Urothelial Carcinoma Cells via Suppressing Bcl-xL: An In Vitro and In Vivo Study
IJMS, Vol. 20, Pages 3218: Trifluoperazine, an Antipsychotic Drug, Effectively Reduces Drug Resistance in Cisplatin-Resistant Urothelial Carcinoma Cells via Suppressing Bcl-xL: An In Vitro and In Vivo Study International Journal of Molecular Sciences doi: 10.3390/ijms20133218 Authors: Kuan-Lin Kuo Shing-Hwa Liu Wei-Chou Lin Fu-Shun Hsu Po-Ming Chow Yu-Wei Chang Shao-Ping Yang Chung-Sheng Shi Chen-Hsun Hsu Shih-Ming Liao Hong-Chiang Chang Kuo-How Huang Cisplatin-based...
International Journal of Molecular Sciences
Sun Jun 30, 2019 03:00
IJMS, Vol. 20, Pages 3217: Reactive Oxygen Species Are Key Mediators of Demyelination in Canine Distemper Leukoencephalitis but not in Theiler’s Murine Encephalomyelitis
IJMS, Vol. 20, Pages 3217: Reactive Oxygen Species Are Key Mediators of Demyelination in Canine Distemper Leukoencephalitis but not in Theiler’s Murine Encephalomyelitis International Journal of Molecular Sciences doi: 10.3390/ijms20133217 Authors: Attig Spitzbarth Kalkuhl Deschl Puff Baumgärtner Ulrich (1) Background: Canine distemper virus (CDV)-induced demyelinating leukoencephalitis (CDV-DL) in dogs and Theiler’s murine encephalomyelitis (TME) virus...
International Journal of Molecular Sciences
Sun Jun 30, 2019 03:00
IJMS, Vol. 20, Pages 3219: Salt Inducible Kinase Signaling Networks: Implications for Acute Kidney Injury and Therapeutic Potential
IJMS, Vol. 20, Pages 3219: Salt Inducible Kinase Signaling Networks: Implications for Acute Kidney Injury and Therapeutic Potential International Journal of Molecular Sciences doi: 10.3390/ijms20133219 Authors: Mary Taub A number of signal transduction pathways are activated during Acute Kidney Injury (AKI). Of particular interest is the Salt Inducible Kinase (SIK) signaling network, and its effects on the Renal Proximal Tubule (RPT), one of the primary targets of injury in AKI. The...
International Journal of Molecular Sciences
Sun Jun 30, 2019 03:00
IJMS, Vol. 20, Pages 3216: Comparative Investigation of Phenomenological Modeling for Hysteresis Responses of Magnetorheological Elastomer Devices
IJMS, Vol. 20, Pages 3216: Comparative Investigation of Phenomenological Modeling for Hysteresis Responses of Magnetorheological Elastomer Devices International Journal of Molecular Sciences doi: 10.3390/ijms20133216 Authors: Yu Li Li Li Li Wang Magnetorheological elastomer (MRE) is a type of magnetic soft material consisting of ferromagnetic particles embedded in a polymeric matrix. MRE-based devices have characteristics of adjustable stiffness and damping properties,...
International Journal of Molecular Sciences
Sun Jun 30, 2019 03:00
IJMS, Vol. 20, Pages 3215: Polyamine Action under Metal/Metalloid Stress: Regulation of Biosynthesis, Metabolism, and Molecular Interactions
IJMS, Vol. 20, Pages 3215: Polyamine Action under Metal/Metalloid Stress: Regulation of Biosynthesis, Metabolism, and Molecular Interactions International Journal of Molecular Sciences doi: 10.3390/ijms20133215 Authors: Mirza Hasanuzzaman Haifa Abdulaziz S. Alhaithloul Khursheda Parvin M.H.M. Borhannuddin Bhuyan Mohsin Tanveer Sayed Mohammad Mohsin Kamrun Nahar Mona H. Soliman Jubayer Al Mahmud Masayuki Fujita Polyamines (PAs) are found in all living organisms...
International Journal of Molecular Sciences
Sun Jun 30, 2019 03:00
IJMS, Vol. 20, Pages 3214: Absence of MCP-induced Protein 1 Enhances Blood–Brain Barrier Breakdown after Experimental Stroke in Mice
IJMS, Vol. 20, Pages 3214: Absence of MCP-induced Protein 1 Enhances Blood–Brain Barrier Breakdown after Experimental Stroke in Mice International Journal of Molecular Sciences doi: 10.3390/ijms20133214 Authors: Zhuqing Jin Jian Liang Jiaqi Li Pappachan E. Kolattukudy Focal cerebral ischemia can cause blood–brain barrier (BBB) breakdown, which is implicated in neuroinflammation and progression of brain damage. Monocyte chemotactic protein 1–induced protein...
International Journal of Molecular Sciences
Sun Jun 30, 2019 03:00
IJMS, Vol. 20, Pages 3213: Mesoporous Materials: From Synthesis to Applications
IJMS, Vol. 20, Pages 3213: Mesoporous Materials: From Synthesis to Applications International Journal of Molecular Sciences doi: 10.3390/ijms20133213 Authors: Juan Antonio Cecilia Ramón Moreno Tost María Retuerto Millán Mesoporous silica are inorganic materials, which are formed by the condensation of sodium silicate or silicon alkoxides around an ordered surfactant used as template [...]
International Journal of Molecular Sciences
Sun Jun 30, 2019 03:00
IJMS, Vol. 20, Pages 3210: Recent Topics on The Mechanisms of Immunosuppressive Therapy-Related Neurotoxicities
IJMS, Vol. 20, Pages 3210: Recent Topics on The Mechanisms of Immunosuppressive Therapy-Related Neurotoxicities International Journal of Molecular Sciences doi: 10.3390/ijms20133210 Authors: Zhang Egashira Masuda Although transplantation procedures have been developed for patients with end-stage hepatic insufficiency or other diseases, allograft rejection still threatens patient health and lifespan. Over the last few decades, the emergence of immunosuppressive agents such as...
International Journal of Molecular Sciences
Sat Jun 29, 2019 03:00
IJMS, Vol. 20, Pages 3212: Tumor Microenvironment as A “Game Changer” in Cancer Radiotherapy
IJMS, Vol. 20, Pages 3212: Tumor Microenvironment as A “Game Changer” in Cancer Radiotherapy International Journal of Molecular Sciences doi: 10.3390/ijms20133212 Authors: Magdalena Jarosz-Biej Ryszard Smolarczyk Tomasz Cichoń Natalia Kułach Radiotherapy (RT), besides cancer cells, also affects the tumor microenvironment (TME): tumor blood vessels and cells of the immune system. It damages endothelial cells and causes radiation-induced inflammation. Damaged vessels inhibit the...
International Journal of Molecular Sciences
Sat Jun 29, 2019 03:00
IJMS, Vol. 20, Pages 3211: Mangifera indica L. Leaf Extract Induces Adiponectin and Regulates Adipogenesis
IJMS, Vol. 20, Pages 3211: Mangifera indica L. Leaf Extract Induces Adiponectin and Regulates Adipogenesis International Journal of Molecular Sciences doi: 10.3390/ijms20133211 Authors: Giuseppe Sferrazzo Rosa Palmeri Luca Vanella Lucia Parafati Simone Ronsisvalle Antonio Biondi Francesco Basile Giovanni Li Volti Ignazio Barbagallo Natural bioactive compounds may be used in obese patients because of their ability to impact on various key mechanisms involved in...
International Journal of Molecular Sciences
Sat Jun 29, 2019 03:00
IJMS, Vol. 20, Pages 3209: A Chronic Ocular-Hypertensive Rat Model induced by Injection of the Sclerosant Agent Polidocanol in the Aqueous Humor Outflow Pathway
IJMS, Vol. 20, Pages 3209: A Chronic Ocular-Hypertensive Rat Model induced by Injection of the Sclerosant Agent Polidocanol in the Aqueous Humor Outflow Pathway International Journal of Molecular Sciences doi: 10.3390/ijms20133209 Authors: Román Blanco Gema Martinez-Navarrete Consuelo Pérez-Rico Francisco J. Valiente-Soriano Marcelino Avilés-Trigueros Javier Vicente Eduardo Fernandez Manuel Vidal-Sanz Pedro de la Villa Background: To induce a moderate chronic...
International Journal of Molecular Sciences
Sat Jun 29, 2019 03:00
IJMS, Vol. 20, Pages 3208: Basic Concepts on the Role of Nuclear Factor Erythroid-Derived 2-Like 2 (Nrf2) in Age-Related Diseases
IJMS, Vol. 20, Pages 3208: Basic Concepts on the Role of Nuclear Factor Erythroid-Derived 2-Like 2 (Nrf2) in Age-Related Diseases International Journal of Molecular Sciences doi: 10.3390/ijms20133208 Authors: Fabiane Valentini Francisqueti-Ferron Artur Junio Togneri Ferron Jéssica Leite Garcia Carol Cristina Vágula de Almeida Silva Mariane Róvero Costa Cristina Schmitt Gregolin Fernando Moreto Ana Lúcia A. Ferreira Igor Otávio Minatel Camila Renata Correa The...
International Journal of Molecular Sciences
Sat Jun 29, 2019 03:00
IJMS, Vol. 20, Pages 3207: Potential Utility of Biased GPCR Signaling for Treatment of Psychiatric Disorders
IJMS, Vol. 20, Pages 3207: Potential Utility of Biased GPCR Signaling for Treatment of Psychiatric Disorders International Journal of Molecular Sciences doi: 10.3390/ijms20133207 Authors: Hidetoshi Komatsu Mamoru Fukuchi Yugo Habata Tremendous advances have been made recently in the identification of genes and signaling pathways associated with the risks for psychiatric disorders such as schizophrenia and bipolar disorder. However, there has been a marked reduction in the pipeline...
International Journal of Molecular Sciences
Sat Jun 29, 2019 03:00
IJMS, Vol. 20, Pages 3206: Preventive Effects of Tryptophan–Methionine Dipeptide on Neural Inflammation and Alzheimer’s Pathology
IJMS, Vol. 20, Pages 3206: Preventive Effects of Tryptophan–Methionine Dipeptide on Neural Inflammation and Alzheimer’s Pathology International Journal of Molecular Sciences doi: 10.3390/ijms20133206 Authors: Yasuhisa Ano Yuka Yoshino Kazuyuki Uchida Hiroyuki Nakayama Preventive approaches for age-related memory decline and dementia have become a high priority in the aging society because of the lack of therapeutic approaches. Recent epidemiological studies have reported that...
International Journal of Molecular Sciences
Sat Jun 29, 2019 03:00
IJMS, Vol. 20, Pages 3204: The Insulin-Like Growth Factor 2 mRNA Binding Protein IMP2/IGF2BP2 is Overexpressed and Correlates with Poor Survival in Pancreatic Cancer
IJMS, Vol. 20, Pages 3204: The Insulin-Like Growth Factor 2 mRNA Binding Protein IMP2/IGF2BP2 is Overexpressed and Correlates with Poor Survival in Pancreatic Cancer International Journal of Molecular Sciences doi: 10.3390/ijms20133204 Authors: Charlotte Dahlem Ahmad Barghash Philip Puchas Johannes Haybaeck Sonja M. Kessler The insulin-like growth factor 2 (IGF2) mRNA binding protein IMP2 (IGF2BP2) is an oncogenic protein known to be overexpressed in different tumor types....
International Journal of Molecular Sciences
Sat Jun 29, 2019 03:00
IJMS, Vol. 20, Pages 3205: Beneficial Role of HO-1-SIRT1 Axis in Attenuating Angiotensin II-Induced Adipocyte Dysfunction
IJMS, Vol. 20, Pages 3205: Beneficial Role of HO-1-SIRT1 Axis in Attenuating Angiotensin II-Induced Adipocyte Dysfunction International Journal of Molecular Sciences doi: 10.3390/ijms20133205 Authors: Hari Vishal Lakhani Mishghan Zehra Sneha S. Pillai Nitin Puri Joseph I. Shapiro Nader G. Abraham Komal Sodhi Background: Angiotensin II (Ang II), released by the renin–angiotensin–aldosterone system (RAAS), contributes to the modulatory role of the...
International Journal of Molecular Sciences
Sat Jun 29, 2019 03:00
IJMS, Vol. 20, Pages 3203: NB-LRRs Not Responding Consecutively to Fusarium oxysporum Proliferation Caused Replant Disease Formation of Rehmannia glutinosa
IJMS, Vol. 20, Pages 3203: NB-LRRs Not Responding Consecutively to Fusarium oxysporum Proliferation Caused Replant Disease Formation of Rehmannia glutinosa International Journal of Molecular Sciences doi: 10.3390/ijms20133203 Authors: Aiguo Chen Li Gu Na Xu Fajie Feng Dexin Chen Chuyun Yang Bao Zhang Mingjie Li Zhongyi Zhang Consecutive monoculture practice facilitates enrichment of rhizosphere pathogenic microorganisms and eventually leads to the emergence of...
International Journal of Molecular Sciences
Sat Jun 29, 2019 03:00
IJMS, Vol. 20, Pages 3196: Dark Antibacterial Activity of Rose Bengal
IJMS, Vol. 20, Pages 3196: Dark Antibacterial Activity of Rose Bengal International Journal of Molecular Sciences doi: 10.3390/ijms20133196 Authors: Faina Nakonechny Margarita Barel Arad David Simor Koretz Boris Litvak Elena Ragozin Ariel Etinger Oz Livne Yosef Pinhasi Gary Gellerman Marina Nisnevitch The global spread of bacterial resistance to antibiotics promotes a search for alternative approaches to eradication of pathogenic bacteria. One alternative...
International Journal of Molecular Sciences
Sat Jun 29, 2019 03:00

IJMS, Vol. 20, Pages 3198: Endothelial Dysfunction in Chronic Heart Failure: Assessment, Findings, Significance, and Potential Therapeutic Targets
IJMS, Vol. 20, Pages 3198: Endothelial Dysfunction in Chronic Heart Failure: Assessment, Findings, Significance, and Potential Therapeutic Targets International Journal of Molecular Sciences doi: 10.3390/ijms20133198 Authors: Manal M. Alem Chronic heart failure (CHF) is a complex syndrome that results from structural and functional disturbances that affect the ability of the heart to supply oxygen to tissues. It largely affects and reduces the patient’s quality of life, socio-economic...
International Journal of Molecular Sciences
Sat Jun 29, 2019 03:00
IJMS, Vol. 20, Pages 3202: Genetic Defects in Mitochondrial Dynamics in Caenorhabditis elegans Impact Ultraviolet C Radiation- and 6-hydroxydopamine-Induced Neurodegeneration
IJMS, Vol. 20, Pages 3202: Genetic Defects in Mitochondrial Dynamics in Caenorhabditis elegans Impact Ultraviolet C Radiation- and 6-hydroxydopamine-Induced Neurodegeneration International Journal of Molecular Sciences doi: 10.3390/ijms20133202 Authors: Jessica H. Hartman Claudia Gonzalez-Hunt Samantha M. Hall Ian T. Ryde Kim A. Caldwell Guy A. Caldwell Joel N. Meyer Background: Parkinson’s disease (PD) is one of the most common neurodegenerative disorders...
International Journal of Molecular Sciences
Sat Jun 29, 2019 03:00
IJMS, Vol. 20, Pages 3200: How to Modify Drug Release in Paediatric Dosage Forms? Novel Technologies and Modern Approaches with Regard to Children’s Population
IJMS, Vol. 20, Pages 3200: How to Modify Drug Release in Paediatric Dosage Forms? Novel Technologies and Modern Approaches with Regard to Children’s Population International Journal of Molecular Sciences doi: 10.3390/ijms20133200 Authors: Monika Trofimiuk Katarzyna Wasilewska Katarzyna Winnicka In the pharmaceutical technology, paediatric population still presents the greatest challenge in terms of developing flexible and appropriate drug dosage forms. As for many medicines, there...
International Journal of Molecular Sciences
Sat Jun 29, 2019 03:00
IJMS, Vol. 20, Pages 3199: Artificial Saliva: Challenges and Future Perspectives for the Treatment of Xerostomia
IJMS, Vol. 20, Pages 3199: Artificial Saliva: Challenges and Future Perspectives for the Treatment of Xerostomia International Journal of Molecular Sciences doi: 10.3390/ijms20133199 Authors: Dawid Łysik Katarzyna Niemirowicz-Laskowska Robert Bucki Grażyna Tokajuk Joanna Mystkowska The chronic sensation of a dry mouth is a disease condition called xerostomia and affects a large part of the population. Xerostomia is associated with decreased secretion, or more often, qualitative...
International Journal of Molecular Sciences
Sat Jun 29, 2019 03:00
IJMS, Vol. 20, Pages 3197: Telmisartan Inhibits Cell Proliferation and Tumor Growth of Esophageal Squamous Cell Carcinoma by Inducing S-Phase Arrest In Vitro and In Vivo
IJMS, Vol. 20, Pages 3197: Telmisartan Inhibits Cell Proliferation and Tumor Growth of Esophageal Squamous Cell Carcinoma by Inducing S-Phase Arrest In Vitro and In Vivo International Journal of Molecular Sciences doi: 10.3390/ijms20133197 Authors: Takanori Matsui Taiga Chiyo Hideki Kobara Shintaro Fujihara Koji Fujita Daisuke Namima Mai Nakahara Nobuya Kobayashi Noriko Nishiyama Tatsuo Yachida Asahiro Morishita Hisakazu Iwama Tsutomu Masaki Esophageal...
International Journal of Molecular Sciences
Sat Jun 29, 2019 03:00
IJMS, Vol. 20, Pages 3195: A MYB-Related Transcription Factor from Lilium lancifolium L. (LlMYB3) Is Involved in Anthocyanin Biosynthesis Pathway and Enhances Multiple Abiotic Stress Tolerance in Arabidopsis thaliana
IJMS, Vol. 20, Pages 3195: A MYB-Related Transcription Factor from Lilium lancifolium L. (LlMYB3) Is Involved in Anthocyanin Biosynthesis Pathway and Enhances Multiple Abiotic Stress Tolerance in Arabidopsis thaliana International Journal of Molecular Sciences doi: 10.3390/ijms20133195 Authors: Yubing Yong Yue Zhang Yingmin Lyu Most commercial cultivars of lily are sensitive to abiotic stresses. However, tiger lily (Lilium lancifolium L.), one of the most widely distributed wild...
International Journal of Molecular Sciences
Sat Jun 29, 2019 03:00
IJMS, Vol. 20, Pages 3201: The AtHSP17.4C1 Gene Expression Is Mediated by Diverse Signals that Link Biotic and Abiotic Stress Factors with ROS and Can Be a Useful Molecular Marker for Oxidative Stress
IJMS, Vol. 20, Pages 3201: The AtHSP17.4C1 Gene Expression Is Mediated by Diverse Signals that Link Biotic and Abiotic Stress Factors with ROS and Can Be a Useful Molecular Marker for Oxidative Stress International Journal of Molecular Sciences doi: 10.3390/ijms20133201 Authors: Nasser Sewelam Kemal Kazan Meike Hüdig Veronica G. Maurino Peer M. Schenk Reactive oxygen species (ROS) are highly controlled signaling species that are involved in regulating gene expression in response...
International Journal of Molecular Sciences
Sat Jun 29, 2019 03:00
IJMS, Vol. 20, Pages 3193: Derived Polymorphic Amplified Cleaved Sequence (dPACS): A Novel PCR-RFLP Procedure for Detecting Known Single Nucleotide and Deletion–Insertion Polymorphisms
IJMS, Vol. 20, Pages 3193: Derived Polymorphic Amplified Cleaved Sequence (dPACS): A Novel PCR-RFLP Procedure for Detecting Known Single Nucleotide and Deletion–Insertion Polymorphisms International Journal of Molecular Sciences doi: 10.3390/ijms20133193 Authors: Shiv Shankhar Kaundun Elisabetta Marchegiani Sarah-Jane Hutchings Ken Baker Most methods developed for detecting known single nucleotide polymorphisms (SNP) and deletion–insertion polymorphisms (DIP) are dependent...
International Journal of Molecular Sciences
Sat Jun 29, 2019 03:00
IJMS, Vol. 20, Pages 3194: The Effects of Spaceflight Factors on the Human Plasma Proteome, Including Both Real Space Missions and Ground-Based Experiments
IJMS, Vol. 20, Pages 3194: The Effects of Spaceflight Factors on the Human Plasma Proteome, Including Both Real Space Missions and Ground-Based Experiments International Journal of Molecular Sciences doi: 10.3390/ijms20133194 Authors: Alexander G. Brzhozovskiy Alexey S. Kononikhin Lyudmila Ch. Pastushkova Daria N. Kashirina Maria I. Indeykina Igor A. Popov Marc-Antoine Custaud Irina M. Larina Evgeny N. Nikolaev The aim of the study was to compare proteomic data...
International Journal of Molecular Sciences
Sat Jun 29, 2019 03:00
IJMS, Vol. 20, Pages 3192: Galectin 13 (PP13) Facilitates Remodeling and Structural Stabilization of Maternal Vessels during Pregnancy
IJMS, Vol. 20, Pages 3192: Galectin 13 (PP13) Facilitates Remodeling and Structural Stabilization of Maternal Vessels during Pregnancy International Journal of Molecular Sciences doi: 10.3390/ijms20133192 Authors: Marei Sammar Tijana Drobnjak Maurizio Mandala Sveinbjörn Gizurarson Berthold Huppertz Hamutal Meiri Galectins regulate cell growth, proliferation, differentiation, apoptosis, signal transduction, mRNA splicing, and interactions with the extracellular matrix....
International Journal of Molecular Sciences
Sat Jun 29, 2019 03:00
IJMS, Vol. 20, Pages 3190: Carbodiimide Conjugation of Latent Transforming Growth Factor β1 to Superparamagnetic Iron Oxide Nanoparticles for Remote Activation
IJMS, Vol. 20, Pages 3190: Carbodiimide Conjugation of Latent Transforming Growth Factor β1 to Superparamagnetic Iron Oxide Nanoparticles for Remote Activation International Journal of Molecular Sciences doi: 10.3390/ijms20133190 Authors: Obiora Azie Zachary F. Greenberg Christopher D. Batich Jon P. Dobson Conjugation of latent growth factors to superparamagnetic iron oxide nanoparticles (SPIONs) is potentially useful for magnetically triggered release of bioactive macromolecules....
International Journal of Molecular Sciences
Sat Jun 29, 2019 03:00
IJMS, Vol. 20, Pages 3191: Cystathionine-Gamma-Lyase-Derived Hydrogen Sulfide-Regulated Substance P Modulates Liver Sieve Fenestrations in Caecal Ligation and Puncture-Induced Sepsis
IJMS, Vol. 20, Pages 3191: Cystathionine-Gamma-Lyase-Derived Hydrogen Sulfide-Regulated Substance P Modulates Liver Sieve Fenestrations in Caecal Ligation and Puncture-Induced Sepsis International Journal of Molecular Sciences doi: 10.3390/ijms20133191 Authors: Ravinder R Gaddam Stephen Chambers Robin Fraser Victoria C Cogger David G Le Couteur Isao Ishii Madhav Bhatia Cystathionine-γ-lyase (CSE) isa hydrogen sulfide (H2S)-synthesizing enzyme that promotesinflammation...
International Journal of Molecular Sciences
Sat Jun 29, 2019 03:00
IJMS, Vol. 20, Pages 3189: Glucan and Mannan—Two Peas in a Pod
IJMS, Vol. 20, Pages 3189: Glucan and Mannan—Two Peas in a Pod International Journal of Molecular Sciences doi: 10.3390/ijms20133189 Authors: Tatiana A. Korolenko Nataliya P. Bgatova Vaclav Vetvicka In recent decades, various polysaccharides isolated from algae, mushrooms, yeast, and higher plants have attracted serious attention in the area of nutrition and medicine. The reasons include their low toxicity, rare negative side effects, relatively low price, and broad spectrum of...
International Journal of Molecular Sciences
Sat Jun 29, 2019 03:00
IJMS, Vol. 20, Pages 3188: Lipidomics Conquers a Niche, Consolidates Growth
IJMS, Vol. 20, Pages 3188: Lipidomics Conquers a Niche, Consolidates Growth International Journal of Molecular Sciences doi: 10.3390/ijms20133188 Authors: David Touboul Mario Ollero Sixteen years after the first published article in which the term “lipidomics” was stated [...]
International Journal of Molecular Sciences
Sat Jun 29, 2019 03:00
IJMS, Vol. 20, Pages 3187: Protective Effects of Salidroside against Carbon Tetrachloride (CCl4)-Induced Liver Injury by Initiating Mitochondria to Resist Oxidative Stress in Mice
IJMS, Vol. 20, Pages 3187: Protective Effects of Salidroside against Carbon Tetrachloride (CCl4)-Induced Liver Injury by Initiating Mitochondria to Resist Oxidative Stress in Mice International Journal of Molecular Sciences doi: 10.3390/ijms20133187 Authors: Shi-Yu Lin Xu Dan Xia-Xia Du Chong-Lin Ran Xu Lu Shao-Jun Ren Zi-Ting Tang Li-Zi Yin Chang-Liang He Zhi-Xiang Yuan Hua-Lin Fu Xiao-Ling Zhao Gang Shu The antioxidant effect of salidroside has been...
International Journal of Molecular Sciences
Fri Jun 28, 2019 03:00
IJMS, Vol. 20, Pages 3186: Quantitative Biology of Human Shelterin and Telomerase: Searching for the Weakest Point
IJMS, Vol. 20, Pages 3186: Quantitative Biology of Human Shelterin and Telomerase: Searching for the Weakest Point International Journal of Molecular Sciences doi: 10.3390/ijms20133186 Authors: Veverka Janovič Hofr The repetitive telomeric DNA at chromosome ends is protected from unwanted repair by telomere-associated proteins, which form the shelterin complex in mammals. Recent works have provided new insights into the mechanisms of how human shelterin assembles and recruits...
International Journal of Molecular Sciences
Fri Jun 28, 2019 03:00
IJMS, Vol. 20, Pages 3185: Morphological, Transcriptomic and Hormonal Characterization of Trimonoecious and Subandroecious Pumpkin (Cucurbita maxima) Suggests Important Roles of Ethylene in Sex Expression
IJMS, Vol. 20, Pages 3185: Morphological, Transcriptomic and Hormonal Characterization of Trimonoecious and Subandroecious Pumpkin (Cucurbita maxima) Suggests Important Roles of Ethylene in Sex Expression International Journal of Molecular Sciences doi: 10.3390/ijms20133185 Authors: Wang Yan Zou Wang Xu Cui Qu : Sex expression is a complex process, and in-depth knowledge of its mechanism in pumpkin is important. In this study, young shoot apices at the one-true-leaf...
International Journal of Molecular Sciences
Fri Jun 28, 2019 03:00
IJMS, Vol. 20, Pages 3184: Investigations of Accessibility of T2/T3 Copper Center of Two-Domain Laccase from Streptomyces griseoflavus Ac-993
IJMS, Vol. 20, Pages 3184: Investigations of Accessibility of T2/T3 Copper Center of Two-Domain Laccase from Streptomyces griseoflavus Ac-993 International Journal of Molecular Sciences doi: 10.3390/ijms20133184 Authors: Azat Gabdulkhakov Ilya Kolyadenko Olga Kostareva Alisa Mikhaylina Paulo Oliveira Paula Tamagnini Alexander Lisov Svetlana Tishchenko Laccases (EC 1.10.3.2) are multicopper oxidoreductases acting on diphenols and related substances. Laccases are highly...
International Journal of Molecular Sciences
Fri Jun 28, 2019 03:00

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