Κυριακή 22 Μαΐου 2016

SQUAMOUS CELL CARCINOMA OF TONGUE – A CASE REPORT AND REVIEW OF LITERATURE

2016-05-22T23-53-42Z
Source: International Journal of Current Research and Review
L. Kayal, S. Jayachandran, Y. Hemavathy Bhaskar.
Oral Squamous cell carcinoma is the most common cancer of the Oral Cavity and it is usually seen in patients above the age of 50 years. It rarely occurs in patients who are less than 30 years old (0.4-5.5%). Diagnosis in advanced stage, misdiagnosis usually lead to inappropriate treatment and delayed definitive treatment. Studies show that nearly 30-40 % of all cancer-related mortality are due to human behaviors such as smoking, consumption of alcohol, poor diet quality and physical inactivity. The morbidity of this malignant neoplasm is low in young patientsonly about 2 % of patients was diagnosed with tongue cancer in patients under the age of 35 years. This case report describes a squamous cell carcinoma, involving anterolateral border of tongue in young adult.


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Genetic engineering: A new player in genome editing

Nature Reviews Genetics. doi:10.1038/nrg.2016.72

Author: Linda Koch



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Chromatin: Cracking the nucleosome code

Nature Reviews Genetics. doi:10.1038/nrg.2016.70

Author: Bryony Jones



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Cancer genetics: Oncohistone pathology explained

Nature Reviews Genetics. doi:10.1038/nrg.2016.71

Author: Linda Koch



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Genetic variation: Genetic associations with a social science outcome

Nature Reviews Genetics. doi:10.1038/nrg.2016.73

Author: Linda Koch



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First trimester trophoblasts forming endothelial-like tubes in vitro emulate a ‘blood vessel development’ gene expression profile

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Publication date: Available online 21 May 2016
Source:Gene Expression Patterns
Author(s): Amanda R. Highet, Sam Buckberry, Benjamin T. Mayne, Sultana M. Khoda, Tina Bianco-Miotto, Claire T. Roberts
Extravillous cytotrophoblasts isolated from first trimester placenta, and immortalised cell lines derived from them, have the intrinsic ability to form endothelial-like tubes when cultured on Matrigel™ extracellular matrix. This in vitro tube formation may model placental angiogenesis and/or endovascular differentiation by trophoblasts. To interpret the relevance of this phenomenon to placental development, we used a gene expression microarray approach to identify which genes and pathways are associated with the tube-forming phenotype of HTR8/SVneo first trimester trophoblasts (HTR8-M), compared with HTR8/SVneo not forming tubes on plastic culture surface (HTR8-P). Furthermore, we used weighted gene co-expression network analysis (WGCNA) of microarray data to identify modules of co-expressed genes underlying the biological processes. There were 481 genes differentially expressed between HTR8-M and HTR8-P and these were significantly enriched for blood vessel development and related gene ontologies. WGCNA clustered the genes into 9 co-expression modules. One module was significantly associated with HTR8-M (p = 1.15E-05) and contained genes involved in actin cytoskeleton organization, cell migration and blood vessel development, consistent with tube formation on Matrigel. Another module was significantly associated with HTR8-P (p = 1.94E-05) and was enriched for genes involved in mitosis, consistent with proliferation by cells on plastic which do not differentiate. Up-regulation of angiogenesis and vascular development pathways in endovascular trophoblasts in vivo could underpin spiral artery remodelling processes, which are defective in preeclamptic pregnancies.



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Paramedic 2000.00 sign bonus 1 year - First Response

This position is for a moderately busy system working both 911 and non 911 calls in the City of Decatur.

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Survivors meet with Ill. responders who saved their lives

By Adam Poulisse
The Rockford Register Star

ROCKFORD, Ill. — Jeff Williams was fixing a neighbor's water heater on Dec. 22, the day after his birthday, when he almost died.

He had to return to his house to get more tools, but his heart stopped beating as he walked through his neighbor's living room. He doesn't remember anything after collapsing, except waking up in the hospital about a week later.

A neighbor's friend performed CPR until EMTs from the Rockford Fire Department arrived. Williams wasn't able to thank those who saved him — until today.

Williams, 53, was one of several survivors who mingled with and thanked emergency responders at a survivors and responders event hosted by the Fire Department at University of Illinois College of Medicine at Rockford.

"It was great meeting them," Williams said while talking with three of the responders who were there the day he collapsed. "My birthday was Dec. 21, but now I say it's Dec. 22, because they revived me."

For eight years, the annual event has united survivors with the responders who saved their lives. It began in 2008 as a way to recognize faculty and others who saved a heart attack victim at Eisenhower Middle School. It has grown every year since.

"Sometimes it can provide closure to the patient," said Bob Vertiz, event coordinator. "For our own personnel that responds ... this shows with proper training and hard work and determination, good things can happen and work out the way they're supposed to."

Mark Reeser, the driver of the engine that arrived first after Williams collapsed, said the event is "a great opportunity to see people continue their lives."

"Most of them have a new lease on life," he said. "It renews our faith in what we do."

Rockford Fire Chief Derek Bergsten emceed the gathering. Several survivors spoke, including Armando Quinones, who suffered a heart attack in 2012, was revived and continued his love for running at such events as the Boston Marathon. This weekend, he's running in the Rockford Marathon.

"The doctors still don't understand what happened that day," he told the crowd, "but it wasn't my time."

Dave Buse was the most recent survivor attending the event. Last week, while at a hockey game at Riverview Ice House, he was saved by Rockford Park District personnel and off-duty EMTs after going into cardiac arrest.

A video of Buse's story — taped during his stay in the hospital — was shown during the event. No one knew whether he would be able to attend.

He was, and it was an emotional reunion.

"(I) will never be able to thank them," he said. "This is the least I can do. The best I can do is do something with my life from here on out."

Copyright 2016 Rockford Register Star



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Measuring beliefs and satisfaction regarding nursing care among Greek patients on haemodialysis

2016-05-22T11-14-41Z
Source: Journal of Behavioral Health
Elenitsa Ferentinou,, Margarita Giannakopoulou, Panagiotis Prezerakos, Athanassios Sachlas, Paraskevi Theofilou,, Sophia Zyga.
During the last decades an increased interest has taken place intensively with regards to the assessment of patients satisfaction and their beliefs regarding provided nursing care. In the context of the present study, empirical data are presented in a sample of patients with end - stage renal disease undergoing haemodialysis in order to assess their beliefs concerning provided nursing care as well as their level of satisfaction related to the provided services. A questionnaire which has been developed in the context of the current study was used, consisted of seven domains, in order to measure patients satisfaction on maintenance dialysis. 320 questionnaires were totally distributed. The total number of the questionnaires that were filled in and finally returned was 284. Patients evaluated their status of health with 65,51 (±21,562). The majority of patients indicated above average satisfaction with regards to the availability of information before the beginning of haemodialysis as well as the provision of nursing care. It is important to note that a large percent of patients did not indicate satisfaction concerning psychological support provided by health professionals (16,7%), medical care (15,8%), frequency of medical visits (15,8%) as well as the feeling of safety during the session of haemodialysis (15,8%). Patients satisfaction undergoing haemodialysis is a factor of a great importance in the provision of a qualitative nursing care.


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Public Service PTSD PSA video

This video is for everyone that has ran that call they can not shake off. Please watch.

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GoPro Hero Reel: Emergency services in Norway

This is a short movie about the SAR- and emergency services in Tromsø, northern Norway. Starring the ambulance, fire department, police department, the Army, Air ambulance, volunteers (Norwegian People's Aid and Redningsselskapet. And made with a big smile!

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Public Service PTSD PSA video

This video is for everyone that has ran that call they can not shake off. Please watch.

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GoPro Hero Reel: Emergency services in Norway

This is a short movie about the SAR- and emergency services in Tromsø, northern Norway. Starring the ambulance, fire department, police department, the Army, Air ambulance, volunteers (Norwegian People's Aid and Redningsselskapet. And made with a big smile!

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Public Service PTSD PSA video

This video is for everyone that has ran that call they can not shake off. Please watch.

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GoPro Hero Reel: Emergency services in Norway

This is a short movie about the SAR- and emergency services in Tromsø, northern Norway. Starring the ambulance, fire department, police department, the Army, Air ambulance, volunteers (Norwegian People's Aid and Redningsselskapet. And made with a big smile!

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Public Service PTSD PSA video

This video is for everyone that has ran that call they can not shake off. Please watch.

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GoPro Hero Reel: Emergency services in Norway

This is a short movie about the SAR- and emergency services in Tromsø, northern Norway. Starring the ambulance, fire department, police department, the Army, Air ambulance, volunteers (Norwegian People's Aid and Redningsselskapet. And made with a big smile!

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What does EEG tell us about arithmetic strategies? A review

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Publication date: Available online 21 May 2016
Source:International Journal of Psychophysiology
Author(s): Thomas Hinault, Patrick Lemaire




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