Πέμπτη 17 Μαΐου 2018

Genetic Analyses of Elys Mutations in Drosophila Show Maternal-Effect Lethality and Interactions with Nucleoporin Genes

ELYS determines the subcellular localizations of Nucleoporins (Nups) during interphase and mitosis. We made loss-of-function mutations of Elys in Drosophila melanogaster and found that ELYS is dispensable for zygotic viability and male fertility but the maternal supply is necessary for embryonic development. Subsequent to fertilization, mitotic progression of the embryos produced by the mutant females is severely disrupted at the first cleavage division, accompanied by irregular behavior of mitotic centrosomes. The Nup160 introgression from D. simulans shows close resemblance to that of the Elys mutations, suggesting a common role for those proteins in the first cleavage division. Our genetic experiments indicated critical interactions between ELYS and three Nup107-160 subcomplex components; hemizygotes of either Nup37, Nup96 or Nup160 were lethal in the genetic background of the Elys mutation. Not only Nup96 and Nup160 but also Nup37 of D. simulans behave as recessive hybrid incompatibility genes with D. melanogaster. An evolutionary analysis indicated positive natural selection in the ELYS-like domain of ELYS. Here we propose that genetic incompatibility between Elys and Nups may lead to reproductive isolation between D. melanogaster and D. simulans, although direct evidence is necessary.



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Editorial Board



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Editorial Board



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International Organization of Psychophysiology

Publication date: June 2018
Source:International Journal of Psychophysiology, Volume 128





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Editorial Board

Publication date: June 2018
Source:International Journal of Psychophysiology, Volume 128





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Kardioanästhesie 2018 – Wandel als Chance?

Anästhesiol Intensivmed Notfallmed Schmerzther 2018; 53: 329-330
DOI: 10.1055/a-0588-4274



Georg Thieme Verlag KG Stuttgart · New York

Article in Thieme eJournals:
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Kardioanästhesie: Monitoring und aktuelle hämodynamische Konzepte

Anästhesiol Intensivmed Notfallmed Schmerzther 2018; 53: 332-345
DOI: 10.1055/s-0043-106281

Die Krankheitsschwere herzchirurgischer Patienten und die Komplexität der Eingriffe haben in den letzten Jahren deutlich zugenommen. Dies stellt nicht nur erhöhte Anforderungen an die neurologische und hämodynamische Überwachung, sondern macht es auch erforderlich, die hämodynamische Therapie – unter Berücksichtigung aktueller pharmakologischer Entwicklungen – individuell dem höheren Risikoprofil der Patienten anzupassen.
[...]

Georg Thieme Verlag KG Stuttgart · New York

Article in Thieme eJournals:
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Kasuistik: Metamizol-induzierte Agranulozytose

Anästhesiol Intensivmed Notfallmed Schmerzther 2018; 53: 388-394
DOI: 10.1055/s-0043-115329

Metamizol hat insgesamt ein günstiges Nebenwirkungsprofil – aber es birgt ein höheres Risiko einer medikamenteninduzierten Agranulozytose als andere Schmerzmittel und darf daher nicht unkritisch eingesetzt werden. Dieser Beitrag berichtet von einem Patienten, der nach prothetischem Hüftersatz eine medikamenteninduzierte Agranulozytose – mutmaßlich durch Metamizol – entwickelt und trotz maximaler Therapie im septischen Schock verstirbt.
[...]

Georg Thieme Verlag KG Stuttgart · New York

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Kardioanästhesie: Monitoring der Gerinnung und Gerinnungstherapie

Anästhesiol Intensivmed Notfallmed Schmerzther 2018; 53: 364-379
DOI: 10.1055/s-0043-112099

Die Transfusion von allogenen Blutprodukten ist mit einer Erhöhung der perioperativen Morbidität und Letalität assoziiert. Störungen der Hämostase sind insbesondere bei kardiochirurgischen Patienten häufig anzutreffen und können zu transfusionspflichtigen Blutungen führen. Eine zielgerichtete Therapie der häufig komplexen Gerinnungsstörungen erfordert eine differenzierte Diagnostik.
[...]

Georg Thieme Verlag KG Stuttgart · New York

Article in Thieme eJournals:
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Intensivmedizin: Ist ein hohes CRP ein geeigneter Prädiktor für ein postoperatives Delir?

Anästhesiol Intensivmed Notfallmed Schmerzther 2018; 53: 324-327
DOI: 10.1055/a-0607-6157



Georg Thieme Verlag KG Stuttgart · New York

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Kolloide zur Volumentherapie nach Verbrennung geeignet?

Anästhesiol Intensivmed Notfallmed Schmerzther 2018; 53: 324-324
DOI: 10.1055/a-0607-6170



Georg Thieme Verlag KG Stuttgart · New York

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Hypertone Lösungen bei hämorrhagischem Schock ohne gesicherten Vorteil

Anästhesiol Intensivmed Notfallmed Schmerzther 2018; 53: 327-328
DOI: 10.1055/a-0607-6183



Georg Thieme Verlag KG Stuttgart · New York

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Kardioanästhesie: anästhesiologisches Management

Anästhesiol Intensivmed Notfallmed Schmerzther 2018; 53: 346-362
DOI: 10.1055/s-0043-106337

Das anästhesiologische Management herzchirurgischer Patienten hat sich in den letzten Jahren deutlich weiterentwickelt. Diese Übersicht widmet sich vor allem folgenden Bereichen: pharmakologische Kardioprotektion bei herzchirurgischen Eingriffen, Narkosemanagement an der Herz-Lungen-Maschine, Protokolle der „Enhanced Recovery After Cardiac Surgery" sowie innovative minimalinvasive Operationsverfahren wie die kathetergestützte Aortenklappenimplantation.
[...]

Georg Thieme Verlag KG Stuttgart · New York

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Hypotonie nach Spinalanästhesie zur Sectio: Noradrenalin oder Phenylephrin?

Anästhesiol Intensivmed Notfallmed Schmerzther 2018; 53: 328-328
DOI: 10.1055/a-0607-6144



Georg Thieme Verlag KG Stuttgart · New York

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Erratum: Atemwegsmanagement – der schwierige Atemweg beim thoraxchirurgischen Patienten

Anästhesiol Intensivmed Notfallmed Schmerzther
DOI: 10.1055/a-0613-2898



Georg Thieme Verlag KG Stuttgart · New York

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Obere Altersgrenze bei ambulanter Anästhesie: Möglichkeiten und Risiken

Anästhesiol Intensivmed Notfallmed Schmerzther 2018; 53: 380-386
DOI: 10.1055/s-0042-124408

Zahlreiche Operationen werden heute auch noch in höherem Lebensalter ambulant durchgeführt. Dieser Übersichtsartikel stellt die Vorteile der ambulanten Anästhesie bei älteren Patienten dar, zeigt aber auch die Risiken einer zu frühen Entlassung auf. Für den klinischen Alltag werden praktische Hilfestellungen für die Patientenauswahl gegeben und Risikofaktoren für eine ungeplante stationäre Aufnahme identifiziert.
[...]

Georg Thieme Verlag KG Stuttgart · New York

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Pssst … AINS-Secrets: heute aus der Urologie – TUR-Syndrom

Anästhesiol Intensivmed Notfallmed Schmerzther 2018; 53: 395-398
DOI: 10.1055/s-0042-101662



Georg Thieme Verlag KG Stuttgart · New York

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Sauerstoffgabe für die Mutter bei Kaiserschnitt und oxidativer Stress des Kindes

Anästhesiol Intensivmed Notfallmed Schmerzther 2018; 53: 322-322
DOI: 10.1055/a-0607-6131



Georg Thieme Verlag KG Stuttgart · New York

Article in Thieme eJournals:
Table of contents  |  Full text



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Liver-related mortality in hepatitis delta patients: Russian single centre experience



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Hemangiolymphangioma of the small bowel: a rare cause of chronic anemia



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LONG EXTENSIVE RADIATION PROCTITIS TREATED WITH RECTAL BAND LIGATION (with video)



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Liver-related mortality in hepatitis delta patients: Russian single centre experience



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Hemangiolymphangioma of the small bowel: a rare cause of chronic anemia



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LONG EXTENSIVE RADIATION PROCTITIS TREATED WITH RECTAL BAND LIGATION (with video)



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Interchangeability of counts of cases and hours of cases for quantifying a hospital's change in workload among four-week periods of 1 year

Recent studies have made longitudinal assessments of case counts using State (e.g., United States) and Provincial (e.g., Canada) databases. Such databases rarely include either operating room (OR) or anesthesia times and, even when duration data are available, there are major statistical limitations to their use. We evaluated how to forecast short-term changes in OR caseload and workload (hours) and how to decide whether changes are outliers (e.g., significant, abrupt decline in anesthetics).

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5 ways to empower your EMS employees

Create a culture of recognition and invest in the proper equipment to support your EMS personnel

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A Case Report of Kernicterus in a Neonate with Hemolytic Disease of Newborn—Lessons to Learn

Neonatal jaundice is a common but usually benign finding in most newborns. Bilirubin at high levels may lead to bilirubin encephalopathy (BE) and kernicterus (Watchko & Tiribelli, 2013). The term kernicterus was initially used to describe a characteristic pattern of central yellow staining in the brain of neonates at autopsy with severe hyperbilirubinemia, defined variably as either 25 mg/dl or greater or 30 mg/dl or greater (American Academy of Pediatrics, Subcommittee on Hyperbilirubinemia, 2004; Johnson & Bhutani, 2011; Wusthoff & Loe, 2015).

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Assessing the Longer-Term Effects of Mild Traumatic Brain Injury on Self-Reported Driving Ability

Mild traumatic brain injury (mTBI) may have long-term cognitive and functional consequences, and recent mTBI is associated with impaired performance on measures related to driving ability. However, it remains unclear whether prior mTBI history is associated with poorer driving performance.

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Peer Respites: A Qualitative Assessment of Consumer Experience

Abstract

This qualitative study explored the experiences of persons staying at two peer respites through interviews with 27 respite guests near the end of their stay and at 2–6 months following their stay. Trained peer interviewers conducted baseline and follow-up interviews. Peer respites can be beneficial spaces within the mental health system for guests to temporarily escape stressful situations while building relationships with other persons with mental illness, though some respondents were uncomfortable receiving services from peers, and several guests did not want to leave after their stay. Ongoing training of peers and orientations for respite guests can help ensure optimal respite experiences.



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Wiedemann‐Steiner syndrome as a major cause of syndromic intellectual disability: A study of 33 French cases

Clinical Genetics, EarlyView.


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Effect of centrally acting angiotensin converting enzyme inhibitor on the exercise‐induced increases in muscle sympathetic nerve activity

The Journal of Physiology, EarlyView.


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Absent metaboreflex‐induced increases in sympathetic outflow to contracting muscle

The Journal of Physiology, EarlyView.


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Efficacy of a dexmedetomidine–remifentanil combination compared with a midazolam–remifentanil combination for conscious sedation during therapeutic endoscopic retrograde cholangio-pancreatography: A prospective, randomized, single-blinded preliminary trial

Digestive Diseases and Sciences

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Hepatic IRS1 and ß-catenin expression is associated with histological progression and overt diabetes emergence in NAFLD patients

Journal of Gastroenterology

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Systematic review with meta-analysis: Change in liver stiffness during anti-viral therapy in patients with hepatitis B

Digestive and Liver Diseases

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Surgical outcome and hepatic regeneration after hepatic resection for hepatocellular carcinoma in elderly patients

Digestive Surgery

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Henoch-Schönlein purpura with acute pancreatitis: Analysis of 13 cases

BMC Pediatrics

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Role of positron emission tomography in assessing disease activity in ulcerative colitis: Comparison with biomarkers

Digestive Diseases and Sciences

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A subclinical high tricuspid regurgitation pressure gradient independent of the mean pulmonary artery pressure is a risk factor for the survival after living donor liver transplantation

BMC Gastroenterology

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Increased expression of senescence-associated cell cycle regulators in the progression of biliary atresia: An immunohistochemical study

Histopathology

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Fecal immunochemical test for predicting mucosal healing in ulcerative colitis patients: A systematic review and meta-analysis

Journal of Gastroenterology and Hepatology

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Outcomes of endoscopic resection for superficial duodenal epithelial neoplasia

Gastrointestinal Endoscopy

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Delayed‐onset muscle soreness in human masticatory muscles increases inhibitory jaw reflex responses

Journal of Oral Rehabilitation, Volume 45, Issue 6, Page 430-435, June 2018.


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Issue Information

Journal of Oral Rehabilitation, Volume 45, Issue 6, Page ii-iv, June 2018.


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Cover Image

Journal of Oral Rehabilitation, Volume 45, Issue 6, Page i-i, June 2018.


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Umbilical resection during laparoscopic surgery for urachal remnants

Asian Journal of Endoscopic Surgery, EarlyView.


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Primary lumbar hernia: A rare case report and a review of the literature

Asian Journal of Endoscopic Surgery, EarlyView.


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Injuries Among Recreational Football Players: Results of a Prospective Cohort Study

imageObjectives: To establish the incidence and patterns of football injuries and associated consequences in daily life and labor loss, among public employees. Design: Prospective cohort study. Setting: Football tournament between public employees in Turkey. Participants: A total of 1821 recreational players from 78 teams. Main Outcome Measures: Injury rates (injuries per 1000 hours of football exposure) during tournament by age group, as well as prevalence, severity, and injury types were recorded. The data regarding the occurrence (eg, location, type, circumstances) and consequences (eg, absenteeism, medical treatment, labor loss) of injuries were collected. Results: Of the 1821 football players registered for participation, 57% (n = 1038) were included in the study with the returned questionnaire forms. In total, 257 matches were played with a total exposure time of 5654 hours. A total of 218 injuries were recorded in 192 players (10.5%), resulting in a mean of 0.85 time-loss injuries per match (38.6 per 1000 hours). Severe injuries constituted 42.6% of all injuries, and 28.9% of all injuries caused the participants to be absent at least 1 day for the next working day. The total labor loss was 1196 days for all injuries. The rate of missing subsequent working day was significantly less for muscle injuries (P

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Effect of E-Bike Versus Bike Commuting on Cardiorespiratory Fitness in Overweight Adults: A 4-Week Randomized Pilot Study

imageObjective: To assess if active commuting with an electrically assisted bicycle (e-bike) during a 4-week period can induce increases in cardiorespiratory fitness measured as peak oxygen uptake (V[Combining Dot Above]O2peak) in untrained, overweight individuals, and if these changes are comparable with those induced by a conventional bicycle. Design: Four-week randomized pilot study. Setting: Controlled laboratory. Participants: Thirty-two volunteers (28 men) participated. Seventeen {median age 37 years [interquartile range (IQR) 34, 45], median body mass index [BMI] 29 kg/m2 [IQR 27, 31]} were randomized to the E-Bike group and 15 [median age 43 years (IQR 38, 45), median BMI 28 kg/m2 (IQR 26, 29)] to the Bike group. Interventions: Participants in both groups were instructed to use the bicycle allocated to them (e-bike or conventional bicycle) for an active commute to work in the Basel (Switzerland) area at a self-chosen speed on at least 3 days per week during the 4-week intervention period. Main Outcome Measures: V[Combining Dot Above]O2peak was assessed before and after the intervention in an all-out exercise test on a bicycle ergometer. Results: V[Combining Dot Above]O2peak increased by an average of 3.6 mL/(kg·min) [SD 3.6 mL/(kg·min)] in the E-Bike group and by 2.2 mL/(kg·min) [SD 3.5 mL/(kg·min)] in the Bike group, with an adjusted difference between the 2 groups of 1.4 mL/(kg·min) [95% confidence interval, −1.4-4.1; P = 0.327]. Conclusions: E-bikes may have the potential to improve cardiorespiratory fitness similar to conventional bicycles despite the available power assist, as they enable higher biking speeds and greater elevation gain.

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AMSSM Position Statement on Cardiovascular Preparticipation Screening in Athletes: Current Evidence, Knowledge Gaps, Recommendations, and Future Directions Erratum.

No abstract available

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Near Point of Convergence and Gait Deficits in Adolescents After Sport-Related Concussion

imageObjective: To prospectively examine gait characteristics of participants acutely after concussion with and without receded near point of convergence (NPC), compared with healthy controls. Design: Cross-sectional study. Setting: Sports-medicine clinic. Participants: Patients examined after concussion (n = 33; mean ± SD = 7.2 ± 3.1 days) and a group of uninjured athletes (n = 31) completed a Postconcussion Symptom Scale, underwent NPC testing, and single/dual-task gait assessments. Independent Variables: Near point of convergence was defined as the patient-reported diplopia distance when a fixation target moved toward the nose. Receded NPC was defined as a distance >5 cm from the tip of the nose. Main Outcome Measures: Spatiotemporal gait characteristics in single-task and dual-task conditions were evaluated with analysis of variance; correlations were calculated between NPC and gait measures. Results: Eighteen of 33 (55%) patients with concussion presented with receded NPC. Those with receded NPC exhibited slower gait speed (single-task = 1.06 ± 0.14 m/s vs 1.19 ± 0.15 m/s; dual-task = 0.80 ± 0.13 m/s vs 0.94 ± 0.13 m/s; P = 0.003) and shorter stride lengths (single-task = 1.11 ± 0.10 m vs 1.24 ± 0.11 m; dual-task = 0.97 ± 0.11 m vs 1.09 ± 0.11 m; P = 0.001) than healthy controls. Near point of convergence was moderately correlated with dual-task average walking speed for the normal NPC group (ρ = −0.56; P = 0.05). Postconcussion Symptom Scale scores did not significantly differ between groups (27 ± 18 vs 28 ± 16). Conclusions: After concussion, adolescents with receded NPC exhibited significant gait-related deficits compared with healthy controls, whereas those with normal NPC did not. Vergence and gross motor system dysfunction may be associated after concussion. Gait and vergence measures may contribute useful information to postconcussion evaluations.

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Physiotherapist-Led Physical Activity Interventions Are Efficacious at Increasing Physical Activity Levels: A Systematic Review and Meta-analysis

imageObjective: Physical activity (PA) interventions to address noncommunicable disease (NCD) risk are commonly delivered in private practice and outpatient physiotherapy settings. This study reviewed the efficacy of physiotherapist-led physical activity (PLPA) interventions at improving PA levels. Data sources: Twelve databases were searched using terms related to both physiotherapy and PA. English-language studies of all designs in adults were included. Meta-analyses were conducted separately for interventions measuring the following: (1) participants meeting recommended PA levels; (2) total PA at short- and long-term follow-up; and (3) total PA achieved after short and long PLPA interventions. Pooled effects were calculated using a fixed-effects model as standardized mean differences (SMDs). Nonstatistical analysis was used to identify the effect of PLPA interventions on the volume of PA performed at different intensities. Main Results: From an initial 4140 studies, 8 were retained, and risk of bias ranged from low to high. Meta-analysis showed the odds of adults meeting minimum recommended PA levels were doubled in groups provided a PLPA intervention [OR = 2.15, 95% confidence interval (CI) = 1.35-3.43]. Total PA levels were increased in the short term (SMD = 0.15, 95% CI = 0.03-0.27) but not in the long term. Longer term interventions did not improve outcomes. Nonstatistical analysis identified that PLPA interventions were efficacious at increasing the amount of PA adults performed at all intensities. Conclusions: Clinic-based PLPA interventions delivered in private practice, primary care, and outpatient settings were efficacious at increasing PA in adults at risk of NCDs. Improvements did not last long term and were not enhanced with longer interventions.

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Atopy in Elite Endurance Athletes

imageObjective: To assess the frequency of atopy (specific IgE levels), to evaluate the allergic symptoms using the Allergy Questionnaire for Athletes (AQUA), and to determine whether atopy is associated with allergic symptoms in elite endurance athletes. Design: Cross-sectional study. Setting: Assessments were performed at Hospital das Clinicas—São Paulo University Medical School. Participants: Fifty-nine elite endurance athletes (triathletes and runners). Main Outcome Measures: Allergic symptoms were assessed by a validated self-report AQUA questionnaire and atopy by specific IgE level. Results: The frequency of atopy (specific IgE to at least one inhalant allergen) and allergic symptoms was 57.6% and 54.2%, respectively. In addition, no association was observed between atopy and allergic symptoms. Conclusions: A possible implication from our results is that atopy screening in elite athletes should be performed using AQUA questionnaire and measuring specific IgE simultaneously.

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2018 CASEM Injury Prevention Podium

No abstract available

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Lightheadedness After Concussion: Not All Dizziness is Vertigo

imageObjective: To characterize the presence and degree of postconcussion lightheadedness in relation to postconcussion vertigo and dizziness, and to determine whether lightheadedness influences overall symptom duration. Design: Prospective, cohort design. Setting: Nationwide Children's Hospital, Sports Concussion Clinic. Participants: Five hundred ten patients (9-19 years of age) within 30 days of concussion injury. Main Outcome Measures: Patient ratings (scale 0-6) of multiple postconcussion symptoms including lightheadedness, vertigo, and dizziness, reported from the day of clinic evaluation and recalled from the day of concussion. Results: Postconcussion lightheadedness occurred commonly relative to vertigo. Lightheadedness was recalled more than vertigo (70.8% vs 48.6%, P

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Return to Driving After Hip Arthroscopy

imageObjective: The objective of this study was to evaluate patients' braking performance using a modern driving simulator after undergoing a right hip arthroscopy. Design: This prospective study included 5 total driving sessions at which measurements were taken. Setting: The study was conducted at an academic medical center. Patients: A total of 14 patients scheduled to undergo a right hip arthroscopy were enrolled and compared with a control group of 17 participants to account for a potential learning phenomenon. Interventions: Patients drove in the simulator preoperatively to establish a baseline, and then drove again at 2, 4, 6, and 8 weeks postoperatively. The control group did not undergo any type of surgical procedure. The main independent variable was time from surgery. Main Outcome Measures: A modern driving simulator was used to measure initial reaction time (IRT), throttle release time (TRT), foot movement time (FMT), and brake travel time (BTT). The braking reaction time (BRT) was calculated as the sum of IRT + TRT + FMT, and the total braking time (TBT) was calculated as the sum of BRT + BTT. Results: The experimental group showed no significant changes in BTT (P = 0.11, JOURNAL/cjspm/04.02/00042752-201805000-00009/math_9MM1/v/2018-05-15T044632Z/r/image-tiff = 0.04) nor TBT (P = 0.20, JOURNAL/cjspm/04.02/00042752-201805000-00009/math_9MM2/v/2018-05-15T044632Z/r/image-tiff = 0.03) over the duration of 8 weeks. Although the experimental group did exhibit significant improvements in IRT (P = 0.002), TRT (P

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Compression Socks Worn During Flight and Hemostatic Balance in Boston Marathon Runners on Oral Contraceptives

imageObjective: To investigate the effect of oral contraceptive (OC) use and compression socks on hemostatic activation in women flying cross-country to and from a marathon. Design: Prospective study. Setting: 2015 Boston Marathon. Participants: Women were divided into non-OC using (CONTROL; n = 12), OC-using (OC; n = 15), and OC-using plus compression sock (OC + SOCK; n = 14) groups. Intervention: Women in OC + SOCK wore compression socks during flights to and from the marathon. Main Outcome Measures: Venous blood samples were collected within 24 hours of arriving in Boston (EXPO), immediately after the marathon (RUN), and within 24 hours after a return flight home (Post-Flight) for analysis of thrombin–antithrombin complex (TAT), d-dimer, and tissue plasminogen activator (t-PA). Results: TAT did not increase with exercise (P = 0.48) and was not affected by group (P = 0.08) or the interaction between these 2 factors (P = 0.80). Group, time, and their interaction were significant for d-dimer (all P

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Quadriceps Tendon-Bone or Patellar Tendon-Bone Autografts When Reconstructing the Anterior Cruciate Ligament: A Meta-analysis

imageObjective: We aimed to quantitatively assess the outcomes of studies, comparing the use of Bone-patellar tendon-bone (BPTB) and the quadriceps tendon-bone (QTB) autografts when reconstructing the anterior cruciate ligament (ACL). Data Sources: MEDLINE, Embase, and CINAHL databases were searched for relevant articles published between January 1980 and January 2015 for the purpose of identifying studies comparing BPTB and QTB autografts for ACL reconstruction. Included studies were assessed regarding their methodological quality before analysis. Outcomes analyzed were graft failure rates, objective and subjective stability assessments, as well as the presence and severity of donor site morbidity. Main Results: Five studies contributed to the quantitative analysis of 806 patients with 452 patients included in the BPTB group and 354 patients in the QTB group. Graft failure rates were similar between the 2 groups [odds ratio (OR) = 0.61; confidence interval (CI) = 0.17-2.15; Z = 0.78, P = 0.44]. There were no significant differences between the 2 groups when testing anteroposterior stability using an arthrometer (standardized mean difference = 0.07; CI = −0.12-0.25; Z = 0.70, P = 0.48). At 1 year postoperatively, there was no difference in the percentage of patients with a positive pivot shift test between the 2 groups (OR = 1.0; CI = 0.85-1.18; Z = 0.01, P = 0.99). However, significantly less patients had graft site pain 1 year after surgery in the QTB group (OR = 0.10; CI = 0.02-0.43; Z = 3.12, P = 0.002). Similarly, fewer patients reported moderate to severe pain while kneeling, in the QTB group (OR = 0.16; CI = 0.07-0.37; Z = 4.26, P

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Trunk Side Strain Has a High Incidence in First-Class Cricket Fast Bowlers in Australia and England

imageObjective: To investigate the past incidence of side strain injury and its associated factors in first-class cricket fast bowlers in Australia and England. Design: Retrospective case series. Setting: Professional cricket. Participants: Cricket fast bowlers who were professionally contracted full time at first-class level in Australia and England in 2011. All bowlers were male and aged 18 or older. A bowler was defined as a fast bowler if the wicketkeeper would take their stance back from the stumps. There were 207 participants. Interventions: Not applicable. Main Outcome Measures: The association between bowling arm, player height, active trunk lateral flexion range of motion, side bridge endurance, volume of first-class cricket played, and the history of injury was determined. Results: Over half of the bowlers had sustained at least 1 side strain in their career. Seventy-seven percent of primary injuries occurred in bowlers aged 24 or under. A higher proportion of injured bowlers had reached first-class volume in their career. Recurrence occurred in 30% of bowlers, with over 30% of these bowlers sustaining at least 1 further recurrence. Nearly half of all recurrences occurred within 2 years with a further quarter in the next year. The injury was not associated with any measured factors. Conclusions: Side strain is a common injury among first-class cricket fast bowlers, especially at younger ages. It was associated with the volume of first-class cricket played. Recurrence was common and occurred most frequently in the first 2 years after primary injury.

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2018 CASEM Podium Presentations

No abstract available

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Underlying Chronic Disease, Medication Use, History of Running Injuries and Being a More Experienced Runner Are Independent Factors Associated With Exercise-Associated Muscle Cramping: A Cross-Sectional Study in 15778 Distance Runners

imageBackground: Exercise-associated muscle cramping (EAMC) is a significant medical complication in distance runners, yet factors associated with EAMC are poorly documented. Objective: To document risk factors associated with EAMC in runners. Design: Cross-sectional study. Setting: Two ocean races (21.1 km, and 56 km). Participants: Fifteen thousand seven hundred seventy-eight race entrants. Methods: Participants completed a prerace medical history screening tool including: training, cardiovascular disease (CVD), risk factors for, and symptoms of CVD, history of diseases affecting major organ systems, cancer, allergies, medication use, and running injury. Runners were grouped as having a history of EAMC (hEAMC group = 2997) and a control group (Control = 12 781). Results: Independent factors associated with a higher prevalence ratio (PR) of hEAMC were any risk factor for CVD (PR = 1.16; P = 0.0002), symptoms of CVD (PR = 2.38; P

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2018 CASEM Poster Presentations

No abstract available

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Firearms, Fiduciaries, and Veterans: Complications of a Flawed Federal Policy Designed to Keep Veterans Safe



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