Δευτέρα, 11 Απριλίου 2016

The anxiety level of chemotherapy receiving patients and their caregivers and affecting factors

2016-04-11T22-25-23Z
Source: TAF Preventive Medicine Bulletin
Seyhan Çıtlık Sarıtaş, Zeliha Büyükbayram.
Aim: This study was performed to examine the anxiety level of chemotherapy receiving patients and their caregivers together with the affecting factors. Methods: The study was conducted as correlational and descriptive in Dicle University Oncology Hospital between June 2013 and July 2014. Chemotherapy patients over the age of 18 and caregivers in Dicle University Oncology Hospital constituted the population of the study. The sample was constituted by 250 chemotherapy receiving patients and 250 caregivers performed power analysis. Patient and caregiver identification form, State and Trait Anxiety Inventory, Edmonton Symptom Scale Diagnostics (Estonian) were used in the data collection. Descriptive statistics, paired t test, independent samples t test, Kruskal-Wallis Variance, Mann-Whitney U, Analysis of Variance (ANOVA) and Pearson Correlation test were used in the evaluation of data. Results: Among the patients who were included to the study, 97.6% were determined to be willing to continue to the treatment and 57.2% were determined to be women. It was found that average anxiety scores of women patients and the people who support the patient in coping with the disease were high and the difference was statistically significant (p


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Evaluation of intraoperative nursing care by patient

2016-04-11T22-25-23Z
Source: TAF Preventive Medicine Bulletin
Semra Eyi, Nevin Kanan, Neriman Akyolcu, Mehmet Levhi Akın, Rengin Acaroğlu.
Aim: The purpose of this study was to evaluate intraoperative nursing care by patients and to determine the effects of patient factors in quality of care. Materials and methods: The Descriptive-Type Study was carried out with a total of 530 patients who underwent operation in The Kasımpaşa Military Hospital between June and December. The data was collected by using Good Perioperative Nursing Care Scale and patient identification forms. Percentage, Number, Mann-Whitney U (separate non-parametric t-tests), Kruskal-Wallis (non-parametric one-way analysis of variance) tests were used to analyze the data. Results: Good Perioperative Nursing Care Scale mean scores of patients was ranged 124,79 ± 25,96. It was found statistically significant that patients who are; male (%81.7), single (%56), having social security system, hospitalized before (%31,7), having planned operation (%96.4), arrive early in the morning of operation (%69.8), gave more positive assessments (p


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Determining the knowledge and opinions of the university student about human papilloma virus vaccine

2016-04-11T22-25-23Z
Source: TAF Preventive Medicine Bulletin
Ayşegül Unutkan, Hatice Balcı Yangın.
HPV is diagnosed in almost all cervix cancers. Determining HPV as a risk factor has led to HPV scanning and development of HPV vaccines in the prevention of cervix cancer. Since the risk of HPV infection onset is high during adolescence period, HPV vaccine is called for during adolescence period before sexual act starts. This research aimed to determine the knowledge and opinions of university youth about HPV vaccine. The population of the study comprised of 998 female students at School of Health of DPÜ. The whole population was tried to be reached with random sampling method. 468 students having accepted to participate were applied a questionnaire. The participation rate was 46,90%. The data were analysed using percentage, chi square tests. The age mean of the participant students was 21.07±1.98. It was determined that 68,4% of the students had no knowledge about HPV and 56,4% hadnt heard anything about HPV vaccine before. 33,1% stated that they would be vaccinated if it were free of charge. Knowledge levels of the students about HPV showed statistically significant discrepancies according to their departments and grades (p


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Investigation of depression and quality of life in nurses working in hospitals

2016-04-11T22-25-23Z
Source: TAF Preventive Medicine Bulletin
Merve Kızılırmak, Satı Demir.
AIM: The aim of this study was to evaluate depression and quality of life in nurses working in hospital. METHODS: The study was conducted in three hospitals in Eskişehir city center. Participants of the study were 329 nurses working at different departments at hospitals. Data were collected through Nurse Information Form, Beck Depression Scale, and SF-36 Life Quality Scale. Kruskal Wallis test, Bonferroni Correction Mann-Whitney U test, and Spearman correlation analysis were used to analyze the data. RESULTS: 89.7% of nurses participated in the study were female and 28.3% of them were working at surgical departments. 27.7% of them have a working experience of five years or below. 91.2% of nurses were service nurse. Significant differences were found between variables of age, gender, education level, economic level, working duration, participation to social activities, get support for coping with problems experienced at the working units and scores of life quality of nurses. The nurses who were single/widow/divorced/separated, working as service nurse, working at intensive care unit, can not get enough support for coping with problems had higher score of depression. CONCLUSION: Some sociodemographic and working characteristics reduce the quality of life and increases the level of depression of nurses. The study results indicate that performing regular check-ups of nurses, minimizing workplace stressors, supporting solutions for problems experienced at the units and increasing social activities are necessary.


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Firefighter Recruit - Sun Lakes Fire District

SUN LAKES FIRE DISTRICT 25025 S ALMA SCHOOL ROAD SUN LAKES, ARIZONA 85248 Updated: April 11, 2016 Job Classification: Firefighter Recruit The Sun Lakes Fire District is accepting applications for Firefighter recruit. The application period will begin April 11, 2016 and all testing through National Testing Network (NTN) must be completed by May 6, 2016 at 4:00 pm. Candidates do not need to fill out the ...

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Find Telrepco at booth #’s 20 & 21 at the CPCA 2016 Public Safety Expo on April 21

We hope to see you next week at the Connecticut Police Chiefs Association 2016 Public Safety Expo on April 21st at The Aqua Turf in Plantsville, CT! We will be at Booths 20 & 21 displaying new and refurbished Panasonic Toughbooks and related accessories, the Panasonic Arbitrator in-car video and the newly introduced Panasonic Body Worn Camera, as well as new Getac ruggedized laptops and tablets ...

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Firefighter/EMS - Central Mason Fire and EMS

CENTRAL MASON FIRE & EMS 122 WEST FRANKLIN STREET SHELTON, WASHINGTON 98584 http://www.cmfe.org Updated: April 07, 2016 Job Classification: Firefighter/EMT The Central Mason Fire & EMS is currently building an ongoing eligibility list for Firefighter/EMT. This position requires FireTEAM through National Testing Network (NTN) and a valid CPAT. Salary Information: Entry Firefighter/EMT $5069.00 ...

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Firefighter/EMT - Star Fire Protection District

STAR FIRE PROTECTION DISTRICT 10831 WEST STATE STREET STAR, IDAHO 83669 Updated: April 08, 2016 Job Classification: Firefighter/EMT The Star Fire Protection District is currently building an eligibility list for Entry Level Firefighter/EMT. All testing through National Testing Network (NTN)must be completed by May 14, 2016 by 10PM. Salary Information: Recruit (First Year of employment) - $36,000.00 ...

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Paramedic Lorie Burton treats a suspect, after he almost shot her husband

The Ohio paramedic treated and forgave the man who came inches away from killing her husband a day earlier

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Paramedic Lorie Burton treats a suspect, after he almost shot her husband

The Ohio paramedic treated and forgave the man who came inches away from killing her husband a day earlier

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Paramedic Lorie Burton treats a suspect, after he almost shot her husband

The Ohio paramedic treated and forgave the man who came inches away from killing her husband a day earlier

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Mitral kapak replasmanı yapılan parkinsonlu hastada anestezi yönetimimiz- enteral l-dopa uygulaması: Olgu sunumu ve literatürlerin incelenmesi

2016-04-11T21-06-54Z
Source: Gulhane Medical Journal
Mehmet Burak ESKIN, Vedat YILDIRIM, Ercan KURT.



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Intraoral lipoma – A rare case presentation

2016-04-11T21-06-54Z
Source: Gulhane Medical Journal
Dr. Anusha Rangare Lakshman, Dr. Sham Kishor Kanneppady, Dr. Preethi Balan.
Lipomas are the benign soft tissue neoplasms of mature adipose tissue. Most of them develop in the subcutaneous tissues, sometimes deeper tissues may be involved as well; the oral cavity is uncommonly involved. About 20% of lipomas occur in the head and neck region among which oral lipomas comprise only 1-4% of all lipomas. Oral lipomas are most commonly seen involving the major salivary glands, buccal mucosa, lip, tongue, palate, vestibule, and floor of mouth. Although it is a benign neoplasm, their progressive growth may cause interference with speech and mastication. Here with, the present paper reports a rare case of intraoral lipoma in 36 year old female patient.


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Radiation-Induced Angiosarcoma Following Breast Conservation Therapy: Case Report

2016-04-11T21-06-54Z
Source: Gulhane Medical Journal
Doğan ALHAN, Serbülent GÜZEY, Andaç AYKAN, Ramazan YILDIZ, İsmail ŞAHİN, Selçuk IŞIK.
Radiation-induced angiosarcoma is a well-known complication of radiotherapy that follows breast conservation surgery. The prognosis of angiosarcoma after radiotherapy is poor, with a 5-year survival rate of between 10-55 % and with a relapse rate of nearly 92 %. Although surgery is the main treatment option for these tumours, it may be a challenging problem because of the highly aggressive behaviour. Adjuvant and neo-adjuvant chemo/radiotherapy are the other alternative treatment options in inoperable cases. However, their effects have not been clearly defined yet. Herein we report a case of angiosarcoma that arises from previously irradiated breast skin. Patient underwent total mastectomy and skin grafting following incisional biopsy and then wide local re-excision due to local recurrence was performed two months later. But, new recurrence lesions were observed in a more aggressive pattern 2 months later again. Additional surgery could not perform because of the general condition of the patient, who was died at the 6th month after diagnosis. Radiation-induced angiosarcomas are challenging problems with a long latency period and highly aggressive clinical behaviour. Therefore clinicians must be aware of newly developed painless vascular lesions at the irradiated zones of breast conservation therapy patients.


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Breast abscess in adolescent girl: A case report

2016-04-11T21-06-54Z
Source: Gulhane Medical Journal
Ahmet Bolat, Mehmet Saldır, Mustafa Gülgün, Necati Balamtekin.
Breast abscess and mastitis manifest itself as erythema and increase in local temperature. While still small lesions are treated by administering a broad spectrum antibiotic. Abscess drainage may be necessary in patients who do not respond to antibiotics. Majority of the patients with breast abscess in childhood are in the neonatal period. Breast abscess are defined mostly in the neonatal age group but rarely seen in older children. In this paper, a 12 year old girl with breast abscess is presented and it is aimed to draw attention to breast abscess that is infrequent in childhood except the neonatal period. The patient recovered without any complications within two weeks with antibiotic treatment and draining of the abscess by a needle aspiration.


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Celiac disease presented with recurrent invagination in a child: case report

2016-04-11T21-06-54Z
Source: Gulhane Medical Journal
Necati Balamtekin, Mustafa Gülgün, Kemal Kara.
Celiac Disease (CD) is gluten-sensitive, autoimmune chronic enteropathy. Diarrhea, abdominal distention, vomiting and failure to thrive are the classical symptoms of celiac disease. "Atypical" celiac disease can present with uncommon gastrointestinal findings, such as abdominal pain, constipation and non gastrointestinal manifestations. Here we report child with celiac disease presenting with recurrent small bowel intussusception. Delayed short bowel transit time and reduced motility could be responsible for clinical symptoms, which resolved after gluten free diet. Celiac disease should be kept in mind in children with symptoms of small bowel intususception or pseudoobstruction without underlying cause.


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Subtle Bucket-Handle Tear Of A Discoid Lateral Meniscus In A 6 Year Old Girl

2016-04-11T21-06-54Z
Source: Gulhane Medical Journal
Doğan Bek, Burak Ahmet Bilekli, Tolga Ege, Servet Tunay.
We report a subtle bucket-handle tear of discoid lateral meniscus causing knee extension blockage in a 6 year old girl. This rare presentation should be recognised by all orthopaedic surgeons practising arthroscopic surgery.


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Evaluation of the parameters that can be effective on the response to antiviral treatment in patients with chronic hepatitis C

2016-04-11T21-06-54Z
Source: Gulhane Medical Journal
İlhan Cebeci, Alpaslan Tanoglu, Fatih Şahiner, Melih Özel, Kemal Öncü, Yusuf Yazgan, Ahmet Kemal Gürbüz, Levent Demirtürk.
Chronic hepatitis C is an important public health problem due its close relationship with liver cirrhosis and hepatocellular carcinoma. Prediction of positively effective factors to chronic hepatitis C treatment gives the opportunity for the most appropriate, individualized and cost-effective treatment while preventing unnecessary and uneffective treatment interventions. In this study, we aimed to determine the laboratory parameters before treatment and during treatment and their likely effects on sustained viral response. Thirty-four patients with chronic hepatitis C (age between 24 and 67) who received PEG-interferon + ribavirine treatment were included in the study. The relationship between some pretreatment parameters estimated to have influence on response to treatment (age, sex, body mass index, liver enzymes, lipid profile, HCV-RNA load, genotype, liver biopsy results) and sustained viral response were evaluated in this study. Our results suggest that younger patients with lower body weight, lower histologic activity and fibrosis, lower GGT levels and GGT/ALT ratios, lower HCV-RNA loads and those with early viral response have a higher rate of sustained viral response. We also observed in our study that, currently as a first line HCV treatment in our country, success rates of standard combination therapy in HCV treatment are promising.


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Treatment Outcomes and Associated Factors among Tuberculosis Patients in Southwest Ethiopia

2016-04-11T21-06-54Z
Source: Gulhane Medical Journal
Tigist Abebe, Mulugeta Tarekegn Angamo.
The aim of this study is to assess treatment outcome and associated factors among tuberculosis patients in Southwest Ethiopia. A five year general retrospective cohort was employed. Data were collected from patients' follow up record and analyzed using SPSS version 16.0(Chicago: SPSS Inc., 2007). P-value 0.05 was considered statistically significant. In the multivariate logistic regression model, age range of (35-44.9 years (AOR=6.5, 95% CI: 3.2-13.4),45-54.9 years (AOR=12.4,95% CI: 5.9-26.2),55-64.9 years (AOR=26.9, 95% CI:11.3-64.2) and ≥65 years (AOR=25.93, 95% CI: 6.9-98.3); male gender (AOR=2.9, 95% CI: 1.9-4.5); rural residence (AOR=3.07, 95% CI: 2.08-4.53);being at prison(AOR=2.67,95% CI: 1.11-6.37);retreatment with anti-tuberculosis medications (AOR=1.9, 95% CI: 1.25-2.89);smear negative tuberculosis (AOR=6.7,95% CI: 4.2-10.7); extra-pulmonary tuberculosis (AOR=5.2, 95% CI: 3.1- 8.7); TB-HIV co-infected patients without co-trimoxazole preventive therapy (AOR=58.6, 95% CI: 6.7-507.8); TB-HIV co-infected patients without antiretroviral treatment(AOR=10.5, 95% CI: 1.4-77.5) were identified as independent risk factors for poor treatment outcomes in the current study. Treatment outcome among tuberculosis patients was satisfactory in the study area. Male gender, age greater than 35 years, smear negative and extra-pulmonary tuberculosis, retreatment with anti-tuberculosis medications, rural residence, being at prison, TB-HIV co-infection without co-trimoxazole preventive therapy and antiretroviral therapy were known to be independent predictors of poor treatment outcomes.


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IONIZED CALCIUM LEVELS IN STROKE PATIENTS AND ITS’ RELATION WITH HEMIPLEGIC UPPER LIMB PAIN

2016-04-11T21-06-54Z
Source: Gulhane Medical Journal
Fatih Tok, Birol Balaban, Evren Yaşar, İsmail Safaz, Bilge Yılmaz, Rıdvan Alaca..
OBJECTIVE: Our aim is to compare the ionized calcium levels between hemiplegic and normal upper limb and to investigate the relationship between forearm pain and ionized calcium levels. MATERIAL AND METHODS 24 stroke patients were included in this study. All of them have spontaneous or evoked forearm pain. Ionized serum calcium levels were analysed in both arms by taking blood from both arms at the same time. Additionally, bone minaral density of both radius were detected. Forearm pains of patients were evaluated with VAS. RESULTS 12 patients were men and others were women. Mean age was 54.33±14.21 years. Serum ionized calcium levels in the hemiplegic side of left hemiplegic patients were significantly less than the levels in right hemiplegic patients. While no correlation was detected between pain and serum ionized calcium levels, negative correlation was detected between radius bone mineral density values and pain levels. CONCLUSION Existence of neuromuscular disorders would be possible when there are changes in amount of active form of calcium. Neuropathic features of hemiplegic forearm pain suggest that decreased calcium levels may increase the intensity of pain which is related to bone mineral loss.


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a heart image extramediastinally shifted to the left pulmonic area

2016-04-11T21-06-54Z
Source: Gulhane Medical Journal
cengiz öztürk, şafak yıldız.
We want to present a heart image extramediastinally shifted to the middle and upper lobe of the left lung due to the former lung infection in a young patient.


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Craniofacial Fibrous Dysplasia: A Case Report

2016-04-11T21-06-54Z
Source: Gulhane Medical Journal
Andaç AYKAN, Serbülent GÜZEY, Fatih ZOR, Bülent DÜZ, Ali Fuat ÇİÇEK, Serdar ÖZTÜRK.
Fibrous Dysplasia is a rare and non-familial disease of the bone. There are different forms of the disease that affect the various anatomic sites. Although the fibrous displasia patients frequently suffer from deformities and pain, there are severe functional losses could be emerged due to the localization of the disease. Because of the clinical variations of the symtomps, there is no standart treatment algoritm for the fibrous dysplasia patients. In this case report, our clinical approach was presented to a case that developed sudden loss of vision due to the craniofacial fibrous dysplasia.


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The reference ranges of neutrophil-lymphocyte ratio in different age groups

2016-04-11T21-06-54Z
Source: Gulhane Medical Journal
İbrahim AYDIN, Mehmet AĞILLI, Fevzi Nuri AYDIN, Yasemin GÜLCAN KURT, Tuncer ÇAYCI, Türker TÜRKER, Necmettin KOÇAK, Ahmet TAŞ, Tevfik HONCA, Taner ÖZGÜRTAŞ.
Neutrophil-lymphocyte ratio is usually considered as an indicator of sub-clinical inflammation. In the recent studies it is observed that neutrophil-lymphocyte ratio can be used to calculate the morbidity and mortality. In this study we aimed to describe the reference values of neutrophil-lymphocyte ratio in different age groups. Patients' records were achieved with the help of Hospital Information System for a year, and 71.897 measurement results which have erythrocyte sedimentation rate and C-reactive protein (CRP) levels within the normal range were included the study. Patients were classified under 11 groups (0-1, 1-2, 2-5, 5-10 age and the rest as decades) according to the age range. Neutrophil-lymphocyte ratio values were calculated by dividing the neutrophil count to lymphocyte count parameter from complete blood count test results. It is found that there were statistically significant differences in eight groups of 11 among the neutrophil-lymphocyte ratio values when male and female patients' results compared. In conclusion, the data obtained from this study may be helpful to clinicians to interpretation of complete blood test is considered.


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Tuba-Ovarian Torsion At Second Trimester Pregnant Woman : A Case Report

2016-04-11T21-06-54Z
Source: Gulhane Medical Journal
Ulaş Fidan, Uğur Keskin, Mustafa Ulubay, Fahri Burçin Fıratlıgil, Ali Ergün.
The diagnosis of tubo-ovarian torsion in pregnancy period is important. Because, symptoms associated with this complication is vague. Particularly, these symptoms in second and third trimester, confusion could expose.In this article, the tubo-ovarian torsion case of a 22 weeks pregnant women offering progressive lower abdominal pain associated with anorexia and nausea was presented. The patient was performed laparatomy and the necrotic mass was removed. In such cases, tubo-ovarian necrosis happened by cause delayed at its diagnosis Eventually, the diagnosis of this complication is to need special attention.


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Congenital cyst which was observed with in patient operated for pelvic mass : case report

2016-04-11T21-06-54Z
Source: Gulhane Medical Journal
Ulaş Fidan, Fahri Burçin Fıratlıgil, Mustafa Ulubay, Uğur Keskin, Ali Ergün.
Paraovarian cysts are usually benign-nature lesions that develop from paramesonephric or mesonephric ducts'remnants and are commonly seen at 4th or 5th decades of life. Paraovarian cysts that are seen in adolescent period, have higher potential to be congenital. Gartner cyst is one of them. Together with gartner cysts, metanephric urinary system abnormalities can be observed. Especially, ectopic ureter, ureter duplication or ectopic kidney abnormalities can be seen. That is why, in pre-operative stage, relations of the cyst with other adjacent organs and other additional organ abnormalities which can accompany with, should be evaluated. Also during the operation, in these cases of potential abnormal ureter traces, cyst should be excised by dissecting carefully. In this case, the management of paraovarian cyst which is observed in 20-year- old, nulligravid lady who had applied to emergency service with complaints of vomiting-nausea, eating disorder, as well as abdominal tenderness, was mentioned.


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Evaluation of The Endoscope Disinfection Effectiveness of Two Different Disinfectants Composed of Benzalkonium Chloride and 0.2% Peracetic Acid

2016-04-11T21-06-54Z
Source: Gulhane Medical Journal
Aslı Toklu, Aysel Gürkan, Alpaslan Tanoğlu, Muammer Kara.
Aim: The aim of this study was to evaluate disinfection efficiencies of disinfectants that are made up of quaternary ammonium compounds (QAC) and 0.2% peracetic acid (PAA) in endoscope disinfection. Materials and Methods: A single-center, prospective cohort work was continued for 12 weeks. Fifty-three endoscopes disinfected with QAC and 51 endoscopes disinfected with 0.2% PAA were included in this study. Samples were collected from endoscopes at both before and after disinfection process. For evaluation of the data, descriptive statistical methods of ratio, mean, standard deviation and for comparison of disinfectants the chi-square test were used. p value lower than 0.05 was accepted as statistically significant. Results: Any procreation of bacteria was detected on the surface and in the both aspiration and air-water channels of the endoscopes disinfected with 0.2% PAA, while some procreation were observed surface and both channels of the endoscopes disinfected with QAC. Statistically significant difference was found between disinfectants in the disinfection efficiencies for both channels (p0.05). Conclusion: It can be concluded that the disinfection efficiency of 0.2% PAA is significantly higher than QAC in endoscope disinfection.


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Gelişimsel kalça displazisine bağlı koksartrozlu hastalarda total kalça artroplasti sonuçlarımız

2016-04-11T21-06-54Z
Source: Gulhane Medical Journal
Öner Tatar, Ömer Erşen, Serkan Bilgiç, Bülent Karslıoğlu, Yüksel Yurttaş, Cemil Yıldız, Mustafa Başbozkurt.
Developmental hip displasia (DHD) still presents as an important problem in our country. Latency in diagnosis and inaccurate treatment causes seconder osteoarthritis in young adults and elder patients. Variable reconstructive surgical procedures as proximal femoral and acetabular osteotomies can be performed, but the most satisfactory functional results are achieved by total hip arthroplasty (THA). In this study, we analyzed the results of the cementless total hip arthroplasties performed in coxarthrosis secondary to developmental hip displasia. Between January 2006 and October 2009, 53 patients diagnosed with hip osteoarthritis secondary to DHD, whom performed 59 total hip arthroplasties were included in the study. 10 of the patients were male (%19), and 43 of them were female(%81). Age of the patients varied between 29 and 78 years and the mean age was 48,7. Totally 10 (%17) complications were observed. 5 (%8,5) of them was intraoperative and 5(%8,5) was postoperative. While preoperative mean Harris score was 39,1, the postoperative mean score measured as 90,3. The results were excellent in 52 cases(%88,1), and very good in 7 cases(%11,9). Appropriate implementation of cementless total hip prosthesis in patients with hip osteoarthritis secondary to DHD, who have good bone quality and surgical indicaton; clinical and radiological short term results were satisfactory.


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Post-Traumatic Intramural Duodenal Hematoma Due To Blunt Abdominal Trauma: Case Report

2016-04-11T21-06-54Z
Source: Gulhane Medical Journal
Batuhan Hazer, Alpaslan Tanoglu, Onur Peşluk, Ayhan İnanlı.
ABSTRACT: Intramural duodenal haematoma (IDH) is a very rare seen complication of healthy adults after blunt abdominal trauma which can be easily overlooked and usually treated with conservative approaches. Intramural duodenal haematoma's are most often treated non-operatively. This post-traumatic complication may occur in cases with bleeding disorders even after minor traumas. The first and most important step in the diagnosis of intramural duodenal haematoma is suspicion of this complication. In this case report, a 20-year-old male subject who was admitted to emergency service with symptoms of gastrointestinal obstruction on 6th day after blunt abdominal trauma and diagnosed as intramural duodenal haematoma. The patient was treated successfully with conservative methods and discharged 14 days later in healthy condition.


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Psychometric evaluation of a Turkısh version of the e-health literacy scale (e-heals) in adolescent

2016-04-11T21-06-54Z
Source: Gulhane Medical Journal
Sabahat Coşkun, Hatice Bebiş.
The young people who are closely associated with the internet are an ideal group for the testing e health literacy measurement. The purpose of this study is to make validity and reliability of the turkısh form of e health literacy scale analysis.e- Health literacy scale was developed by Norman and Skinner ın 2006. This study is a methodologic research which is carried out between January and February 2014. This study was carried out with 100 students who are between the ages of 14-21. Data collectıon form ıncludes the guestıons about the students' socio-demographıc characterıstıcs, e health literacy scale and Lıkert type attitude scale about the usıng of ınternet ın adolescents. The linguistic equıvalence of e health literacy scale was examıned. In thıs study the Kaıser-Meyer-Orkın (KMO) coeffıcient was 0,75 and Bartlett sphericity test was 204,5 and p


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Reliability of a spinal metastasis prognostic score to model one-year survival

spinee57008-fig-0001.sml

Predicting survival after surgery for patients with metastatic spine disease can be challenging with multiple variables that can influence a patient's overall survival. Predictive models have been developed to assist clinicians in providing prognosis for patients. Recently, Ghori et al reported a composite model taking into account a modified Bauer score, pre-operative albumin and ambulatory status of patients with spinal metastasis. We sought to assess the reliability and validity of this composite model to predict one-year survival in patients diagnosed with metastatic cancer to the spine using an independent cohort.

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Early beginning for complementary nutrition ın an infant: case report

2016-04-11T21-06-54Z
Source: Gulhane Medical Journal
Necati Balamtekin, Mustafa Gülgün, Sami EKSERT.
Complementary nutrition is usually advised to begin between 4 and 6 months of age. We reported an infant presenting with unknown material in her faeces diagnosed as undigested vegetable fiber due to banana fed by her mother. A 3 months-old girl was presented with with unknown material in her faeces. She was well-developed with normal percentile levels. We learned feeding her with banana by her mother the night before. Gaita microscopy was revealed undigested vegetable fibers. Her parents were informed about complementary nutrition and not to start any food before 4th months in addition to breast milk. Her faeces was normal 1st day after stopping the banana. Physicians should obtain information of infant's feeding in well-baby follow-up from parents in terms of nutrition mistakes which can be resulted in malnutrition.


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Minimally invasive TLIF leads to increased muscle sparing of the multifidus muscle but not the longissimus muscle compared with conventional PLIF- a prospective randomized clinical trial

The authors have prospectively compared two groups of patients following posterior/transforaminal interbody fusion through either a midline (traditional) approach or a Wiltse incision (MIS approach). They studied the changes in the paraspinal musculature using a CT-based technique to evaluate volume atrophy and fatty degeneration following surgery at the index and adjacent levels. Radiographic changes were studied at the 1-week and 12-month time points and clinical parameters were compared at the preoperative, 1-week and 12-month time points.

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A Rare Cause of Ascites: Multiple Myeloma

2016-04-11T21-06-54Z
Source: Gulhane Medical Journal
Kadir Ozturk, Gurkan Celebi, Gokhan Ozgur,Hakan Demirci, Guldem Kilciler.
A 65 year old male patient who have diagnosis of multiple myeloma for three months. The abdominal ultrasonography was performed upon development of swelling in the abdomen and legs prior to the third cycles of chemotherapy treatment. On ultrasonographic examination the liver was normal but there was free fluid in abdomen. In cytological examination of ascites fluid atypical plasma cell was not detected but Ig G Kappa type monoclonal gammopathy was detected in immunofixation electrophoresis of ascites fluid. Ig G was 1520 mg/dl, Kappa total light chain was 399 mg/dl in ascites fluid. Also there was a beta band peak in ascites fluid protein electrophoresis. Lenalidomide (Revlimid) treatment was planned for multiple myeloma and ascites but patient died due to hypotension and acute renal insufficiency.


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Risk Factors Predicting Infectious Lactational Mastitis: Decision Tree Approach versus Logistic Regression Analysis

Abstract

Objectives Lactational mastitis frequently leads to a premature abandonment of breastfeeding; its development has been associated with several risk factors. This study aims to use a decision tree (DT) approach to establish the main risk factors involved in mastitis and to compare its performance for predicting this condition with a stepwise logistic regression (LR) model. Methods Data from 368 cases (breastfeeding women with mastitis) and 148 controls were collected by a questionnaire about risk factors related to medical history of mother and infant, pregnancy, delivery, postpartum, and breastfeeding practices. The performance of the DT and LR analyses was compared using the area under the receiver operating characteristic (ROC) curve. Sensitivity, specificity and accuracy of both models were calculated. Results Cracked nipples, antibiotics and antifungal drugs during breastfeeding, infant age, breast pumps, familial history of mastitis and throat infection were significant risk factors associated with mastitis in both analyses. Bottle-feeding and milk supply were related to mastitis for certain subgroups in the DT model. The areas under the ROC curves were similar for LR and DT models (0.870 and 0.835, respectively). The LR model had better classification accuracy and sensitivity than the DT model, but the last one presented better specificity at the optimal threshold of each curve. Conclusions The DT and LR models constitute useful and complementary analytical tools to assess the risk of lactational infectious mastitis. The DT approach identifies high-risk subpopulations that need specific mastitis prevention programs and, therefore, it could be used to make the most of public health resources.



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Seronegative autoimmune hepatitis in children: Spectrum of disorders

A few children with acute or chronic liver disease display histological features compatible with autoimmune hepatitis, but lack specific serological markers.

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Selenium and Vitamin E together improve intestinal epithelial barrier function and alleviate oxidative stress in heat stressed pigs

Heat stress compromises intestinal epithelial barrier integrity of mammals through mechanisms that may include oxidative stress. Our objective was to test whether dietary supplementation with antioxidants, selenium (Se) and Vitamin E (VE), protects intestinal epithelial barrier integrity in heat stressed pigs. Female growing pigs (n = 48) were randomly assigned to four diets containing from 0.2 ppm Se and 17 IU kg−1 VE (control, NRC recommended), to 1.0 ppm Se and 200 IU kg−1 VE for 14 days. Six pigs from each dietary treatment were then exposed to either thermoneutral 20°C or heat stress (35°C, 09.00-17.00/ 28°C, overnight) conditions for two days. Trans-epithelial electrical resistance (TER) and FITC-dextran (4 kDa; FD4) permeability were measured in isolated jejunum and ileum using Ussing chambers. Rectal temperature, respiration rate, and intestinal HSP70 mRNA abundance increased (all P < 0.001), and respiratory alkalosis occurred, suggesting that pigs were heat stressed. Heat stress also increased FD4 permeability and decreased TER (both P<0.01). These changes were associated with changes indicative of oxidative stress, a decreased glutathione peroxidase (GPX) activity and an increased glutathione disulfide (GSSG): glutathione (GSH) ratio (both P < 0.05). With increasing dosage of Se and VE, GPX-2 mRNA (P = 0.003) and GPX activity (P = 0.049) linearly increased, and the GSSG:GSH ratio linearly decreased (P = 0.037) and the impacts of heat stress on intestinal barrier function were reduced (P < 0.05 for both TER and FD4 permeability). In conclusion, an increase of dietary Se and VE mitigated heat stress impacts on intestinal barrier integrity, associated with a reduction in oxidative stress in pigs.

This article is protected by copyright. All rights reserved



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Metabolomic and proteomic analysis of serum from preterm infants with necrotising entercolitis and late-onset sepsis

Pediatric Research

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The effect of aspirin and nonsteroidal anti-inflammatory drug use after diagnosis on survival of oesophageal cancer patients

British Journal of Cancer

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Yttrium-90 Microsphere Brachytherapy for Liver Metastases From Uveal Melanoma: Clinical Outcomes and the Predictive Value of Fluorodeoxyglucose Positron Emission Tomography

American Journal of Clinical Oncology

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Rabeprazole, minocycline, amoxicillin, and bismuth as first-line and second-line regimens for Helicobacter pylori eradication

Helicobacter

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Access to subspecialty care and survival among patients with liver disease

The American Journal of Gastroenterology

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Trends in the use of endoscopic retrograde cholangiopancreatography for the management of chronic pancreatitis in the United States

Journal of Clinical Gastroenterology

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Is the prevalence of colonic neuroendocrine tumors increased in patients with inflammatory bowel disease?

International Journal of Cancer

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Diagnostic yield of 24-hour esophageal manometry in non-cardiac chest pain

Neurogastroenterology & Motility

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Multiple siRNAs against HCV and host genes are more effective in inhibition of HCV replication

International Journal of Infectious Diseases

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Population attributable fractions of risk factors for hepatocellular carcinoma in the United States

Cancer

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Glycemic index and glycemic load and risk of colorectal cancer: a population-based cohort study (JPHC Study)

Cancer Causes and Control

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High-dose hepatitis B immunoglobulin therapy in hepatocellular carcinoma with hepatitis B virus-DNA/hepatitis B e antigen-positive patients after living donor liver transplantation

World Journal of Gastroenterology

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Endoscopic and histologic response to cyclosporine in ulcerative colitis and their impact on disease outcome: A cohort study

Digestive and Liver Diseases

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Membrane localization of human equilibrative nucleoside transporter 1 in tumor cells may predict response to adjuvant gemcitabine in resected cholangiocarcinoma patients

The Oncologist

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Macrophage activation marker, soluble CD163 is an independent predictor of short-term mortality in patients with cirrhosis and bacterial infection

Liver International

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Fatty Liver, Insulin Resistance, and Obesity: Relationships With Increase in Coronary Artery Calcium Over Time

Clinical Cardiology

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Vascularizing lymph node dissection for advanced gastric cancer: A single-institution experience

World Journal of Gastroenterology

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Is the Stretta procedure as effective as the best medical and surgical treatments for gastro-oesophageal reflux disease? A best evidence topic

International Journal of Surgery

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The benefit of chemotherapy in esophageal cancer patients with residual disease after trimodality therapy

American Journal of Clinical Oncology

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Gut microbiota profiling of pediatric NAFLD and obese patients unveiled by an integrated meta-omics based approach

Hepatology

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A study of etiological aspect of epilepsy in non-paediatric patients

2016-04-11T01-19-35Z
Source: International Journal of Advances in Medicine
Harshit Acharya, Rashmi Chovatia.
Background: Epilepsy is a neurological condition characterized by the recurrence of paroxysmal episode of abnormal neuronal function. Epilepsy brings in undesirable social, psychological and economical consequences to its patients. In contrast to early onset of epilepsy in childhood, late onset of epilepsy is usually symptomatic; which usually responds well to antiepileptic drugs. Methods: A prospective study of 75 patients of late onset epilepsy was carried out to ascertain the etiology and to evaluate the usefulness of neuroimaging in late onset epilepsy. Results: We found that majority (72%) of patients of late onset epilepsy were male. About 65% of patients had abnormal CT scan-brain findings. Generalized seizure was the most common seizure type with about 59% cases. Conclusions: Generalized seizures are more common in idiopathic group of epilepsy whereas partial with or without secondary generalized seizures are more common in the symptomatic late onset epilepsy. The new neuroimaging techniques should be an integral part of investigation work up in all cases of epilepsy as they make it possible to find out the etiology in majority of cases. In late onset epilepsy, diagnostic usefulness of EEG is corroborative to CT and MRI.


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A study among pulmonary tuberculosis patients under the treatment of DOTS with special reference to liver function in tertiary care hospital

2016-04-11T01-19-35Z
Source: International Journal of Advances in Medicine
C. Paranthakan, P. K. Govindarajan.
Background: Directly observed treatment short course is the most effective life saving measure among the patients suffering from tuberculosis. Drug induced hepatotoxicity is one of the major side of anti-tuberculosis drugs which causes to withdraw the drugs. The objective of the study was to find out certain variables like age, sex and BMI among the patients with pulmonary tuberculosis and to find out liver function after intake of anituberculosis drugs. Methods: The patients diagnosed first time with pulmonary tuberculosis by sputum positive attending RNTCP DOTS Cell at tertiary care hospital were selected for this study.95 patients enrolled in this study during six months period and they were followed another six months to find out the status of liver function. BMI was measured, the investigation like serum albumin, liver function (aspartate aminotransferase (AST), alanine aminotransferase (ALT) alkaline phosphatase level test (ALP), serum bilirubin) were assessed at the time of initiation of anti-tuberculosis drugs and 2 weeks, 4 weeks and 24 weeks after the drugs. Chi-square test applied as a statistical tool. Results: Among study population of 95, 54% were male and 46% were female. Nearly 62% of the patients were in the age group of 18 to 48. Around 57% of the patients were underweight according to BMI. The liver function test was abnormal after drugs in 5.2% of the study population. Conclusions: This study shows that the tuberculosis affects the productive life of the population. The drugs given under DOTS did not harm majority of the patients that shows it is safe to administer the regime.


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Clinical profile and outcome of urinary tract infection caused by extended spectrum beta-lactamase producing Escherichia coli in critically ill patients in a tertiary care hospital in South India: a case control study

2016-04-11T01-19-35Z
Source: International Journal of Advances in Medicine
Jayaprakash Subramani, Anand Janagond.
Background: Infections with Extended spectrum beta-lactamase (ESBL) producing organisms have been associated with poor outcome. Our aim of this study is to compare clinical profile of Urinary tract infection (UTI) caused by ESBL producing Escherichia coli (E. coli) with Non-ESBL producing E. coli. Methods: Retrospective analysis of patients admitted in Intensive care unit in a tertiary care hospital was done. 50 Patients with ESBL producing E. coli infection were assigned as cases; 50 Patients with Non-ESBL producing E. coli were assigned as controls. Clinical characteristics of UTI caused by both ESBL & non-ESBL producing E. coli in critically ill patients and their clinical outcome were observed. Mortality risk on admission was calculated using sepsis scoring system. Results: Most patients in both groups were in 6th and 7th decade. Male to female ratio in both groups were almost similar. Incidence of complications was higher in ESBL group. Mortality rate was 10% in ESBL group; 4% in Non-ESBL group. Mean duration of ICU stay was 4.2 days (ESBL) and 3.1 days (Non-ESBL). APACHE IV and SOFA scoring system mortality prediction accuracy was 60% in both groups. Conclusions: Initiation of empirical therapy with carbapenem antibiotics on admission in critically ill with UTI showed significant impact on mortality. Mean duration of ICU stay in ESBL group was longer than non-ESBL group which is statistically significant. Mortality risk was predicted by APACHE IV & SOFA scores on admission with good accuracy.


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Clinical study of diabetic patients with special reference to their glycemic status

2016-04-11T01-19-35Z
Source: International Journal of Advances in Medicine
Amith Kumar Pendurth, Srjana Karumanchi.
Background: India is the worlds diabetes capital. The prevalence of type 2 diabetes mellitus is expected to raise more rapidly in the future in India and 40 other countries because of increasing obesity and reducing activity levels and other lifestyle changes. To study the profile of diabetic patients with special reference to their glycemic status was the objective of the study. Methods: One hundred patients of diabetes were studied at NRI Medical College and General Hospital, Chinakakani, Guntur. Among diabetics, the criteria were considered to include the patients for the study. The selected patients were studied in detail with history and physical examination. Results: The mean age of male patients in the study was 54.82±12.38 years and that of the female patients was 54.82 ±11.08 years. The mean age of detection of diabetes mellitus among the male patients was 48.84±10.11years and in the female patients was 48.75 ±8.68 years. The mean duration of DM is not statistically significant between male and female patients with P=0.930. 22 patients had good glycemic control of which 14 patients had duration of diabetes less than 5 yrs. Conclusions: Incidence of poor glycemic status has a statistically significant association with the longer duration of diabetes.


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HS-C reactive protein and red blood cell distribution width as effective markers for hypertension

2016-04-11T01-19-35Z
Source: International Journal of Advances in Medicine
G. Pavan Kumar Reddy, Kande V. Mallikarjuna Rao.
Background: Hypertension or elevated blood pressure is one of the leading causes of morbidity and mortality. Hs-CRP, which is a known marker for CVD, is also one of the predictive markers of inflammation processes which result in hypertension. Increased RDW is also believed to be associated with CVD morbidity and mortality in patients with previous myocardial infarction, brain vascular disease, strokes, septicemia, chronic obstructive pulmonary disease and hepatitis B. Methods: 200 patients 100 male and 100 females and 50 each of controls were selected for the study. Complete demographic details were collected from all the patients including the age, sex, height, weight, BMI, smoking/non-smoking status, alcoholism etc. After a thorough clinical examination, venous blood was collected from all the patients after an overnight fast for lipid profile, hs-CRP and complete blood count. Results: The patients in both males and females had a higher BMI than that of the controls. Hs-CRP levels in males was 1.64 mg/L and in females it was 1.47 mg/L. Significant difference was seen in the RDW values also in the patients. Conclusions: Hs-CRP levels and RDW levels are both equally effective as a predictive marker for hypertension.


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Study of serum albumin as surrogate marker of immune suppression in patients living with HIV and AIDS

2016-04-11T01-19-35Z
Source: International Journal of Advances in Medicine
Shiv Shankar Sharma, Yogendra Jamra, Sanjay Hawaldar, Ankit Meshram.
Background: HIV/AIDS being a life long illness requires regular monitoring. CD4+cell counts and HIV RNA levels have been widely accepted as the most reliable indicators of HIV disease progression but these tests are not readily available and costly too. This study examines that whether Serum albumin levels can be used as a surrogate marker for HIV disease monitoring as an alternate to CD4 cell count and HIV viral load measurements in low resource set-up. Methods: This prospective observational study was conducted at a tertiary care hospital in Central India. We studied a total of 100 PLHIV (patients living with HIV and AIDS). Correlation of CD4 count was done with serum albumin levels at baseline and at follow-up visits. Results: Several studies have suggested that albumin could serve as a useful marker of HIV disease progression in resource-limited settings. In the present study, the baseline and follow up values of albumin and CD4 counts were obtained. It was found to have a strong positive correlation amongst them with low CD4 cell counts being associated with lower serum albumin concentrations. Conclusions: The results of this study suggest that serum albumin levels have potential to be used as a surrogate low-cost prognostic marker for HIV disease monitoring in resource-limited settings where frequent estimation of CD4 cell count and HIV viral load is not possible.


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