Σάββατο 25 Ιουνίου 2016

Predisposition or side effect of the duration: the reactivity of the HPA-axis under psychosocial stress in panic disorder

Publication date: Available online 25 June 2016
Source:International Journal of Psychophysiology
Author(s): Gloria-Beatrice Wintermann, Clemens Kirschbaum, Katja Petrowski

Graphical abstract

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Comparative Evaluation of Anti-Obesity Effect of Aloe vera and Gymnema sylvestre Supplementation in High Fat Diet Fed C57BL/6J Mice

2016-06-25T17-20-20Z
Source: Journal of Intercultural Ethnopharmacology
Ramesh medical Pothuraju, Raj Kumar Sharma, Sarver Ahmed Rather, Satvinder Singh.
Background: The aim of the present study was to investigate, anti-obesity effect of comparative evaluation of Aloe vera and Gymnema sylvestre extract powders administration in high fat diet (HFD) fed C57BL/6J mice for 12 weeks. Methods: At the end of experiment, different parameters such as body weight, feed intake, organ weights, fasting blood glucose, oral glucose tolerance test (OGTT), plasma lipid levels and expression analysis of adipocytokines were evaluated. Results: At the end of experimental period, oral administration of herbs showed a significant (p


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Treatment of haemorrhoids with individualized homoeopathy: an open observational pilot study

2016-06-25T17-20-20Z
Source: Journal of Intercultural Ethnopharmacology
Kaushik Deb Das, Shubhamoy Ghosh, Asim Kumar Das, Aloke Ghosh, Ramkumar Mondal, Tanapa Banerjee, Seikh Sajid Ali, Seikh Swaif Ali, Munmun Koley, Subhranil Saha.
Aim: Controversies and disagreement exist on conventional treatment strategies of haemorrhoids due to relapse, inefficacy, and complications. We intend to evaluate role of individualized homoeopathic treatment in haemorrhoids. Methods: In this prospective, open, observational trial, haemorrhoids patients were treated using 5 standardized scales measuring complaints severity and anoscopic score. It was conducted at two homoeopathic hospitals in India during mid-July 2014 to mid-July 2015. Patients were intervened as per individualized homoeopathic principles and followed up every month up to 6 months. Results: Total 73 were screened, 52 enrolled, 38 completed, 14 dropped out. Intention to treat population (n=52) was analyzed in the end. Statistically significant reductions of mean bleeding [month 3: -21.8, 95% CI -30.3, -13.3, P


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DNA Protective Effect of Ginseng and the Antagonistic Effect of Chinese Turnip: A Supplementation Study

2016-06-25T17-20-20Z
Source: Journal of Intercultural Ethnopharmacology
Yim Tong Szeto, Kam Shing Wong, Andrea Han, Sok Cheon Pak, Wouter Kalle.
Aim: In the current study, commercial ginseng extract would be used for supplementing volunteers. DNA protective activity on human lymphocytes mediated by ginseng would be compared with or without the presence of Chinese turnip. Methods: Seven healthy subjects (4 males & 3 females from 37-60 years) after overnight fasting gave 2 mL of blood. Content of 5 ginseng capsules in 200 mL water was then ingested and the subject remained fasting for 2 hours until the second blood sample taken. The subjects were arranged to participate the second part of the experiment with at least 2 weeks apart. The subject ingested the same amount of ginseng extract with a piece of cooked turnip (10 grams). The two occasions could be interchanged. Comet assay was performed on two specimens on the same day for evaluation of DNA damage of lymphocyte with or without oxidative stress. Results: For the group with ginseng supplementation, there was a significant decrease in comet score for H2O2 treatment over the 2 hours period while no change in DNA damage for unstressed sample. For the group with ginseng together with turnip supplementation, there was no significant difference in comet score for both H2O2 treatment and PBS treatment. Ginseng extract could reduce DNA damage mediated by H2O2 effectively but this protection effect was antagonized by the ingestion of cooked turnip at the same time. Conclusion: Ginseng extract could protect DNA from oxidative stress in vivo while turnip diminished the protection.


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Heyde's syndrome: association between severe aortic stenosis and anemia

2016-06-25T11-14-14Z
Source: Cukurova Medical Journal
Koutsampasopoulos Konstantinos, Ioannis Vogiatzis.



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Transmesenteric hernia presenting as acute abdomen in a pediatric patient

2016-06-25T06-46-12Z
Source: Case Study and Case Report
Debabrata Das, Dhrubajyoti Maulik, Subuddha Chatterjee, Dev Vrat Singh, Arghya Choudhuri.
A 10 years old male presented with acute onset progressive abdominal pain and bilious vomiting for 2 days, abdominal distension and absolute constipation for last 1 day. Pain started at periumbilical region and then became diffuse. At first pain was intermittent and colicky, later became dull aching and constant. Patient had associated 10-12 episodes of projectile bilious vomiting for last 2 days. There was no past H/O any surgery or chronic illness. On general survey patient was dehydrated and had tachycardia and tachypnoea. On abdominal examination there was abdominal distension, less abdominal movement with respiration, visible peristalsis at epigastric and umbilical region. Hernial orifices were normal. Guarding, generalised tenderness and rebound tenderness was present, hyperperistaltic sound was present. Investigations revealed leucocytosis, straight X-ray abdomen showed multiple air fluid level in central part of abdomen. Patient was resuscitated with IV fluids and exploratory laparotomy was performed. On exploration strangulated jejunum(of 15cm length) was seen 50cm distal to DJ flexure which was seen herniated through a round mesenteric defect (approximated 5cm diameter) adjacent to the strangulated segment. Portion of the gut was gangrenous and non viable.Resection of the affected part of jejunum with end to end jejunojejunal anastomosis done in interrupted single layer extramucosal technique with polyglycolic 3-0.Mesenteric defect was closed. Post - operative recovery was uneventful.


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Testicular morphometry, Sperm Characteristics and Viscera Organ Weights of Rabbits following the Administration of Aqueous Extract of Gmelina arborea Leaves

2016-06-25T05-13-12Z
Source: International Journal of Livestock Research
Adakole Hyacinth Abu, Terzungwe Ahemen, Haaga E..
An experiment was conducted to investigate the effect of aqueous Gmelina arborea leaf extract on testicular morphometry, cauda epididymal sperm characteristics and organ weights of male rabbits. Thirty two (32) rabbit bucks, aged 9-11 weeks with an average weight of 1300g, were randomly allocated to four treatments comprising of varying concentrations (0, 200, 400 and 600ml of extract per liter of water) of Gmelina arborea leaf. Each treatment consisting of 8 animals per group was replicated 8 times with one animal per replicate. Animals were fed aqueous Gmelina arborea leaf extracts for a period of fourteen (14) weeks. At the end of the experimental trial, the bucks were sacrificed and testicular morphometry; caudal epididymal sperm characteristics and viscera organ weights were evaluated. The results showed significant (P


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Operating Rooms Averaging at Least 8 Hours of Cases and Turnovers.

No abstract available

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Cerebral vasospasm: current understanding.

Purpose of review: With recent research trying to explore the pathophysiologic mechanisms behind vasospasm, newer pharmacological and nonpharmacological treatments are being targeted at various pathways involved. This review is aimed at understanding the mechanisms and current and future therapies available to treat vasospasm. Recent findings: Computed tomography perfusion is a useful alternative tool to digital subtraction angiography to diagnose vasospasm. Various biomarkers have been tried to predict the onset of vasospasm but none seems to be helpful. Transcranial Doppler still remains a useful tool at the bedside to screen and follow up patients with vasospasm. Hypertension rather than hypervolemia and hemodilution in 'Triple-H' therapy has been found to be helpful in reversing the vasospasm. Hyperdynamic therapy in addition to hypertension has shown promising effects. Endovascular approaches with balloon angioplasty and intra-arterial nimodipine, nicardipine, and milrinone have shown consistent benefits. Endothelin receptor antagonists though relieved vasospasm, did not show any benefit on functional outcome. Summary: Endovascular therapy has shown consistent benefit in relieving vasospasm. An aggressive combination therapy through various routes seems to be the most useful approach to reduce the complications of vasospasm. Copyright (C) 2016 YEAR Wolters Kluwer Health, Inc. All rights reserved.

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Extradural Hemorrhage Secondary to Skull Pin Fixation Manifesting as Intractable Intraoperative Brain Swelling.

No abstract available

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