Τρίτη 21 Ιανουαρίου 2020
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com, Telephone consultation 11855 int 1193,
1afcn2-ucoco.htmlAccepted Articles Alert_ British Journal of Dermatology.eml 2ar15h-49goz.htmlAccepted Articles Alert_ Clinical and Experimental Dermatology.eml 3a20z8-b4sl2.htmlAccepted Articles Alert_ Journal of Cutaneous Pathology.eml 4a4iyv-l2tx0.htmlActa Biochimica et Biophysica Sinica Advance articles.eml 5auglf-n23zx.htmlActa Biomaterialia _ Volume 103.eml 6aw2es-io6xn.htmlActa Otorrinolaringológica Española _ Volume 71, Issue 1.eml 7afsia-9xzfg.htmlAMEDEO Otorhinolaryngology 20.01.2020 http___www.amedeo.com...
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PharmaceuticsPharmaceutics, Vol. 12, Pages 83: Mesoporous Silica Nanoparticles for the Treatment of Complex Bone Diseases: Bone Cancer, Bone Infection and OsteoporosisPharmaceutics, Vol. 12, Pages 83: Mesoporous Silica Nanoparticles for the Treatment of Complex Bone Diseases: Bone Cancer, Bone Infection and Osteoporosis Pharmaceutics doi: 10.3390/pharmaceutics12010083 Authors: Gisbert-Garzarán Manzano Vallet-Regí Bone diseases, such as bone cancer, bone infection and osteoporosis, constitute a major...
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MedicinaMedicina, Vol. 56, Pages 43: Infracyanine Green vs. Brilliant Blue G in Inverted Flap Surgery for Large Macular Holes: A Long-Term Swept-Source OCT AnalysisMedicina, Vol. 56, Pages 43: Infracyanine Green vs. Brilliant Blue G in Inverted Flap Surgery for Large Macular Holes: A Long-Term Swept-Source OCT Analysis Medicina doi: 10.3390/medicina56010043 Authors: Salvatore Cillino Massimo Castellucci Giovanni Cillino Valentina Sunseri Costanza Novara Francesco Di Pace Maria Vadalà Vincenza Bonfiglio...
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International Journal of Environmental Research and Public HealthIJERPH, Vol. 17, Pages 670: The Impact of Negative Informal Information Before a Change on Performance: A Within-Person ApproachIJERPH, Vol. 17, Pages 670: The Impact of Negative Informal Information Before a Change on Performance: A Within-Person Approach International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17020670 Authors: Xia Jiang Jing Du Jinfan Zhou Yumeng Cui We live in a rapidly changing business...
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AntioxidantsAntioxidants, Vol. 9, Pages 88: Hydroxycinnamyl Derived BODIPY as a Lipophilic Fluorescence Probe for Peroxyl RadicalsAntioxidants, Vol. 9, Pages 88: Hydroxycinnamyl Derived BODIPY as a Lipophilic Fluorescence Probe for Peroxyl Radicals Antioxidants doi: 10.3390/antiox9010088 Authors: Kusio Sitkowska Konopko Litwinienko Herein, we describe the synthesis of a fluorescent probe NB-2 and its use for the detection of peroxyl radicals. This probe is composed of two receptor segments (4-hydroxycinnamyl...
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High-Dose Versus Standard-Dose Influenza Vaccine in Hemodialysis Patients: Butler et al1 found no significant difference in mortality and influenza-related morbidity with high-dose vaccine (HDV) as compared with standard-dose vaccine (SDV) in an analysis of more than 250,000 US Renal Data System patients. Analyses were adjusted for an extensive list of comorbid conditions, but with only 2.6% receiving the HDV, we cannot help but wonder whether there is residual confounding. Our analysis of approximately...
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| New and Recent ArticlesSymbolic, Distributed, and Distributional Representations for Natural Language Processing in the Era of Deep Learning: A SurveyNatural language is inherently a discrete symbolic representation of human knowledge. Recent advances in machine learning (ML) and in natural language processing (NLP) seem to contradict the above intuition: discrete symbols are fading away, erased by vectors or tensors called distributed and distributional representations. However, there is a strict...
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Latest Results for Health Care AnalysisExploring Models for an International Legal Agreement on the Global Antimicrobial Commons: Lessons from Climate AgreementsAbstract An international legal agreement governing the global antimicrobial commons would represent the strongest commitment mechanism for achieving collective action on antimicrobial resistance (AMR). Since AMR has important similarities to climate change—both are common pool resource challenges that require massive, long-term political...
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International journal of basic and clinical endocrinologyMarian Ludgate—the scientist and her festschriftInternational journal of basic and clinical endocrinology2mMark above section as read Latest Results for Maternal and Child Health JournalA Systematic Review of Programs to Promote Aspects of Teen Parents' Self-sufficiency: Supporting Educational Outcomes and Healthy Birth SpacingAbstract Introduction Expectant and parenting teens experience many challenges to achieving self-sufficiency and promoting...
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Detection of difficult airway using deep learningAbstract Whenever a patient needs to enter the operating room, in case the surgery requires general anesthesia, he/she must be intubated, and an anesthesiologist has to make a previous check to the patient in order to evaluate his/her airway. This process should be done to the patient to anticipate any problem, such as a difficult airway at the time of being anesthetized. In fact, the inadequate detection of a difficult airway can cause serious complications,...
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Coagulation- and Adsorption-Based Environmental Impact Assessment and Textile Effluent TreatmentAbstract Disposal of industrial effluents (especially the textile industry) into the drains without prior treatment is a common practice that affects aquatic life and pollutes the soil and groundwater quality. Textile effluents contain organic and inorganic pollutants in terms of high pH, suspended and dissolved solids, chemical oxygen demand, heavy metals, and many other contaminants. Therefore, it is...
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Adsorption of Tolaasins, the Toxins Behind Mushroom Bacterial Blotch, by Microbacterium spp. is Insufficient for Its DetoxificationAbstract Tolaasins are lipodepsipeptides secreted by Pseudomonas tolaasii, the causal agent of bacterial blotch on several kinds of cultivated mushrooms. Our previous study reported on tolaasin detoxification by Microbacterium sp. K3-5 as a potential biocontrol of the disease. In this study, the tolaasin-detoxifying activities of various type strains of Microbacterium...
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Rhinology: Simulation Training (Part 2): AbstractPurpose of ReviewRecently, there has been an expansion of novel technologies in simulation training. The aim of this review was to examine existing evidence about training simulators in rhinology, their incorporation into real training programmes and translation of these skills into the operating room. The first part focuses on the virtual and augmented reality simulators. The second part describes the role of physical (i.e. non-computer-based) models...
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Effects of Bovine Lactoferrin on Rat Intestinal Epithelial Cells: Objective: To determine the effects of bovine lactoferrin (bLF) on cell viability, proliferation, and the protective roles in intestinal epithelial cells-6 (IEC-6) treated by lipopolysaccharide (LPS). Methods: Cell viability and proliferation of IEC-6 were detected by MTT and Brdu assay separately. Cell cycle distribution was analyzed by flow cytometry. Inflammatory cytokines were analysed by real-time PCR and ELISA. Western...
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Treatment with Lycopodium clavatum 200dH Intensifies Kidney and Liver Injury in Mice Infected with Toxoplasma gondii: AbstractThe effects of infection with Toxoplasma gondii vary from asymptomatic to the development of alterations in various organs (including the liver and kidneys) which may be irreversible, and lead to the death of the host. Whereas homeopathy is an alternative and effective method for treating various diseases, including those caused by protozoa, we questioned...
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OSU-A9 induced-reactive oxygen species cause cytotoxicity in duodenal and gastric cancer cells by decreasing phosphorylated nuclear pyruvate kinase M2 protein levels.Related ArticlesOSU-A9 induced-reactive oxygen species cause cytotoxicity in duodenal and gastric cancer cells by decreasing phosphorylated nuclear pyruvate kinase M2 protein levels. Biochem Pharmacol. 2020 Jan 16;:113811 Authors: Chiu CF, Weng JR, Lee SL, Wu CY, Chu PC, Shan YS, Yang HR, Bai LY Abstract Pyruvate kinase M2 (PKM2) is...
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International validation of the EORTC CAT Core: a new adaptive instrument for measuring core quality of life domains in cancer.: Related ArticlesInternational validation of the EORTC CAT Core: a new adaptive instrument for measuring core quality of life domains in cancer.Qual Life Res. 2020 Jan 18;:Authors: Petersen MA, Aaronson NK, Conroy T, Costantini A, Giesinger JM, Hammerlid E, Holzner B, Johnson CD, Kieffer JM, van Leeuwen M, Nolte S, Ramage JK, Tomaszewski KA, Waldmann A, Young T, Zotti P,...
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Platelet-to-lymphocyte ratio predicts therapy outcomes of transarterial chemoembolization plus apatinib in the treatment of advanced hepatocellular carcinoma: To evaluate the predictive value of preoperative biochemical marker [platelet-to-lymphocyte ratio (PLR)] in patients with advanced hepatocellular cancer receiving transarterial chemoembolization (TACE) plus targeted molecular therapy (apatinib) treatment. Clinical records of 134 patients receiving the treatment of TACE + apatinib (TACE-A) and...
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Antitumor activity of triptolide in SKOV3 cells and SKOV3/DDP in vivo and in vitro: This study was designed to investigate the antitumor activity of triptolide in ovarian cancer inoculated with SKOV3 and SKOV3/cisplatin (DDP) cells, and to assess the mechanisms. In-vivo and in-vitro experiments were designed to evaluate the effects of triptolide on the tumor growth of SKOV3 and SKOV3/DDP cells. The experiments were divided into four groups: a SKOV3 group, a SKOV3 + TP treatment group, a SKOV3/DDP...
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Metastatic intracranial solitary fibrous tumors/hemangiopericytomas: description of two cases with radically different behaviors and review of the literature: Solitary fibrous tumor/hemangiopericytoma with primary tumor location in the central nervous system accounts for less than 1% of all central nervous system tumors. Despite the relatively indolent clinical course, extracranial metastases are reported in 28% of cases. In recent years, NAB2-STAT6 gene fusion has been recognized as the pathognomonic...
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GSE124632 DNA methylation analysis in oropharyngeal cancer [EPIC array]: Contributors : Takuya Nakagawa ; Masaki Fukuyo ; Atsushi KanedaSeries Type : Methylation profiling by genome tiling arrayOrganism : Homo sapiensDNA methylation analysis in oropharyngeal squamous carcinoma (OPSCC) samples and oropharyngeal non-cancerous mucosa samples. Infinium MethylationEPIC BeadChip Kit was used to obtain DNA methylation profiles across more than 850,000 CpG sites. Total samples included 89 OPSCC samples...
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GSE126957 The regeneration transcriptome of corticospinal neuronsContributors : Gunnar H Poplawski ; Riki Kawaguchi ; Giovanni Coppola ; Mark TuszynskiSeries Type : Expression profiling by high throughput sequencingOrganism : In the present study, we identify transcriptional mechanisms associated with corticospinal regeneration. We took advantage of the ability of NPC grafts to support corticospinal regeneration, together with a genetic mouse model (Glt25d2-GFP-L10a mice, in which a bacterial artificial...
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Cognitive dysfunction and subjective symptoms in patients with arachnoid cyst before and after surgery: AbstractIntroductionArachnoid cysts are congenital, benign lesions in the brain and are often incidental radiological findings. Frequently, the arachnoid cysts are left untreated; however, recent studies have shown that arachnoid cysts can cause cognitive dysfunction that affect quality of life. Moreover, the function can improve after surgical decompression. Hence, there is controversy regarding...
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Microsurgical resection of a radicular hemangioblastoma with subarachnoid hemorrhage: how I do it: AbstractBackgroundHemangioblastomas (HBL) are benign tumors occurring sporadically or associated with Von Hippel-Lindau syndrome (VHL).MethodWe present the pre-, per-, and postoperative course of a rare case with radicular HBL presenting with subarachnoid hemorrhage (SAH) in the frame of VHL. We describe the microsurgical approach.ConclusionComplete microsurgical in bloc resection has been performed....
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Quality of life effects of pain from para-lumbar- and lower extremity entrapment syndrome and carpal tunnel syndrome and comparison of the effectiveness of surgery: AbstractIntroductionWe compared the preoperative quality of life (QOL) of patients with carpal tunnel syndrome, lower extremity-, and para-lumbar entrapment syndrome, and the effect of surgery on their QOL.Patients and methodsWe prospectively enrolled 66 consecutive patients who underwent surgery for carpal tunnel syndrome (group 1, n = 23),...
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EANS Basic Brain Course (ABC): combining simulation to cadaver lab for a new concept of neurosurgical training: AbstractBackgroundNeurosurgical training has traditionally been based on an apprenticeship model that requires considerable time and exposure to surgeries. Unfortunately, nowadays these requirements are hampered by several limitations (e.g., decreased caseload, worktime restrictions). Furthermore, teaching methods vary among residency programs due to cultural differences, monetary restrictions,...
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Surface characterization and bonding properties of milled polyetheretherketone dental posts: AbstractPEEK has been used in many dental applications except intra-radicular post. The aim of this study is to test polyetheretherketone (PEEK) as a dental post material through tensile bond strength (TBS) and surface roughness (SR), and to compare it with glass-fiber and cast-metal posts. Thus, 60 human maxillary central incisors with a single root were endodontically treated and divided into three groups...
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Growth hormone releasing hormone in the unfolded protein response context: AbstractThe effects of Growth Hormone Releasing Hormone in human pathophysiology are not limited to those mediated by the Growth Hormone Releasing Hormone–Growth Hormone–Insulin-like Growth Factor-I axis. Receptors specific for this neuropeptide are expressed in a diverse variety of human tissues, to initiate multifarious signaling cascades, regulators of cellular homeostasis and survival. The Unfolded Protein Response is...
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Prognostic value of an inflammatory biomarker-based clinical algorithm in septic patients in the emergency department: An observational study.: CONCLUSIONS: This proposed simple-to-use nomogram based on age, NLR, PLR, LMR and RDW provides a relatively accurate mortality prediction for septic patients in the ED. PMID: 31955067 [PubMed - as supplied by publisher] (Source: International Immunopharmacology)
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Baicalin and its nanoliposomes ameliorates nonalcoholic fatty liver disease via suppression of TLR4 signaling cascade in mice.: In this study, Methionine and choline deficient diet (MCD)-induced NAFLD mice were treated with baicalin or baicalin-loaded nanoliposomes (BA-NL), then hepatic histopathological changes, biochemical parameters and inflammatory molecules were observed. We found that mice in MCD group showed significant increases in plasma transaminase, hepatocyte apoptosis, hepatic lipid...
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V δ2 T cell subsets, defined by PD-1 and TIM-3 expression, present varied cytokine responses in acute myeloid leukemia patients.: In this study, we showed that the frequencies of PD-1+TIM-3- Vδ2 T cells were comparable between healthy controls and AML patients, but the frequencies of PD-1-TIM-3+ Vδ2 T cells and of PD-1+TIM-3+ Vδ2 T cells were significantly higher in AML patients than in healthy controls. Both PD-1 and TIM-3 were upregulated upon phosphoantigen + IL-2 activation, but the relative...
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In vivo osseointegration of a randomized trabecular titanium structure obtained by an additive manufacturing technique: AbstractThe additive manufacturing techniques (AM) are able to realize three-dimensional trabecular structures that mimic the trabecular structure of the bone. An in vivo study in sheep was carried out with the aim of assessing the bone response and the trend of osteointegration of a randomized trabecular titanium structure produced by the AM technique. In 6 sheep were implanted...
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Adult stem cell response to doped bioactive borate glass: AbstractBioactive glasses have transformed healthcare due to their versatility. Bioactive borate glass, in particular, has shown remarkable healing properties for both hard and soft tissues. Incorporating dopants into the composition of bioactive glass helps to control mechanical properties, and it increases their usefulness for clinical applications. Using a bioactive borate glass, 13-93B3 (B3), we investigated eleven dopants on the viability...
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Pathophysiology of Vomiting and Esophageal Perforation in Boerhaave's Syndrome: AbstractBackground and AimsBoerhaave's syndrome, involving esophagus rupture, is considered a pathological response to vomiting that may occur just before perforation. However, the mechanism of vomiting and occurrence of this disease have not been clearly demonstrated.MethodsWe identified patients with esophageal perforation between 1995 and 2017 and reviewed endoscopic findings at retching during upper gastrointestinal...
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Gut Dysthymia: Paraneoplastic Chronic Watery Diarrhea: Case Presentation and EvolutionA 27-year-old East Asian woman with history of metastatic thymoma was evaluated for a 2-year history of non-bloody chronic watery diarrhea. As an outpatient, she had been evaluated on multiple occasions due to profuse, watery diarrhea that occurred seven times a day. She underwent colonoscopy after 6 months of symptoms, which was normal except for internal hemorrhoids. Computed tomography (CT) of the abdomen/pelvis...
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Cytogenetics and mutations could predict outcome in relapsed and refractory acute myeloid leukemia patients receiving BCL-2 inhibitor venetoclax: AbstractVenetoclax, a selective B cell leukemia/lymphoma-2 (BCL2) inhibitor, has recently shown activity in relapsed or refractory (R/R) acute myeloid leukemia (AML). Effective biomarkers for identifying patients most likely to respond to venetoclax-based treatment are of clinical utility. In this study, we aimed to evaluate the efficacy and safety profiles...
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Cerebellar tumour-like aggregate of glycosaminoglycans in a MPS IIIB patient: a case report: AbstractIntroductionMucopolysaccharidosis (MPS) IIIB is a lysosomal disorder in which a deficiency in α-N-acetylglucosaminidase impairs the degradation of heparan sulphate, which accumulates in tissues causing multiple organs dysfunction. This disease is associated with significant central nervous system (CNS) abnormalities, but a presentation with a tumour-like lesion has never been reported so far.Clinical...
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Cirrhotic Patients on Mechanical Ventilation Have a Low Rate of Successful Extubation and Survival: AbstractBackground and AimsWe hypothesized that mechanically ventilated cirrhotic patients not only have poor outcomes, but also that certain clinical variables are likely to be associated with mortality. We aimed to describe the predictors of mortality in these patients.MethodsThis observational study examined 113 mechanically ventilated cirrhotic patients cared for at our institution between July...
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Preclinical Evidence of Probiotics in Colorectal Carcinogenesis: A Systematic Review: AbstractBackgroundColorectal cancer, the second major cause of cancer deaths, imposes a major health burden worldwide. There is growing evidence that supports that the use of probiotics is effective against various diseases, especially in gastrointestinal diseases, including the colorectal cancer, but the differences between the strains, dose, and frequency used are not yet clear.AimsTo perform a systematic review...
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Identification of MFI2-AS1, a Novel Pivotal lncRNA for Prognosis of Stage III/IV Colorectal Cancer: AbstractBackgroundLong noncoding RNAs (lncRNAs) have been shown to play pivotal role in pathogenesis and prognosis of cancers. Identification of novel clinical biomarkers in advanced stage colorectal cancer (CRC) is warranted.AimsTo identify potential lncRNAs associated with progression of stage III/IV CRC and illuminate regulatory mechanisms.MethodsDifferentially expressed lncRNAs, mRNAs and miRNAs...
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FISH and chips: a review of microfluidic platforms for FISH analysis: AbstractFluorescence in situ hybridization (FISH) allows visualization of specific nucleic acid sequences within an intact cell or a tissue section. It is based on molecular recognition between a fluorescently labeled probe that penetrates the cell membrane of a fixed but intact sample and hybridizes to a nucleic acid sequence of interest within the cell, rendering a measurable signal. FISH has been applied to, for example, gene...
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Prebiotics metabolism by gut-isolated probiotics: AbstractThere are numerous species of bacteria resides in the lumen of human colon. The word 'colon', resembles colony or the colonization of microbiota of which plays an important role in the fermentation of prebiotics. The standpoint of prebiotic nowadays is well reported for attenuating gut dysbiosis in many clinical studies tested on animals and human. However, because of the huge amount of gut microbiome, the attempt to connect the dots between...
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A systematic review on the role of infrared thermography in the Brown adipose tissue assessment: AbstractBrown adipose tissue (BAT) is an endocrine adipose tissue with attributes to dissipate energy as heat in response to changes in temperature and diet. Infrared thermography (IRT) has been studied in recent years in the assessment of BAT thermogenesis, as an option to positron emission tomography - computed tomography (PET-CT), because of several advantages. We performed a systematic review on the...
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Single, Pauci, and Multi-allergen Testing and Immunotherapy: AbstractPurpose of ReviewAllergy immunotherapy has been a mainstay of treatment of inhalant allergy for years. Controversy still exists regarding best methods of allergy testing and immunotherapy. We aim to review the evidence supporting single-, pauci-, and multi-allergen testing and immunotherapy.Recent FindingsThe efficacy of immunotherapy has been well-established. The majority of research regarding allergy immunotherapy has focused...
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Sleep-Disordered Breathing in Geriatric Populations: AbstractPurpose of ReviewThe prevalence of sleep-disordered breathing has greatly increased in the geriatric population.Recent FindingsThe pathophysiology of sleep-disordered breathing for this population varies from younger populations due to consequences of aging such as loss of neuromuscular tone, soft tissue hypertrophy, and tissue laxity. The importance of treating obstructive sleep apnea is obvious as it is linked to detrimental cardiovascular...
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Hypoxia induced LUCAT1/PTBP1 axis modulates cancer cell viability and chemotherapy response: AbstractBackgroundHypoxic tumors are refractory to DNA damage drugs. However, the underlying mechanism has yet to be elucidated. We aimed to identify lncRNAs that upregulated under hypoxia and their effects on colorectal cancer (CRC).MethodsCRC cells were treated with 1% O2 to identify lncRNAs that upregulated under hypoxia. We integrated these lncRNAs with RNA-seq of 4 paired CRC tissues and TCGA data to...
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Determination of acute oral toxicity of glyphosate isopropylamine salt in rats: AbstractIn this study, we aim to determine the median lethal dose (LD50) of glyphosate isopropylamine salt (GI), which is commonly used in the world and especially in Turkey against to weeds, in male and female rats by using the probit or logit analysis method. A total of 140 Wistar rats were used, including 70 females and 70 males. To determine LD50, the male and female rats were randomized into 7 groups made up of 10...
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Heavy metal bioaccumulation and morphological changes in Vachellia campechiana (Fabaceae) reveal its potential for phytoextraction of Cr, Cu, and Pb in mine tailings: AbstractVachellia campechiana (Mill Seigler & Ebinger) is widely distributed in Mexico and is a dominant species of tailings in Huautla, in the state of Morelos, Mexico. Mining activities carried out in this region generated about 780 thousand tons of bioavailable heavy metal waste (HMs) that were deposited in the environment without...
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Association of intronic polymorphisms (rs1549339, rs13402242) and mRNA expression variations in PSMD1 gene in arsenic-exposed workers: AbstractUbiquitin-proteasome system (UPS) gene, PSMD1, is an important gene for neutralization of damaged and misfolded protein(s). The current study was designed to study the genetic and expression variations of PSMD1 gene as a consequence of arsenic exposure and its potential implications in arsenic induced diseases. In the present study, 250 blood samples of exposed...
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Copper removal from wastewater by a chitosan-based biodegradable composite: AbstractThis work demonstrates that a biodegradable chitosan-based biocomposite packed in mini-reactors successfully removes copper ions from aqueous solutions. The chitosan is obtained by deacetylation of biological chitin, which is extracted from shrimp wastes by lactic acid fermentation. The polysaccharide is embedded in a biodegradable prepolymer matrix before extrusion to produce porous cylindrical pellets of 2 × 80 mm....
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Infertility, gravidity, and risk of diabetes among high-risk women in the Diabetes Prevention Program Outcomes Study.: Related ArticlesInfertility, gravidity, and risk of diabetes among high-risk women in the Diabetes Prevention Program Outcomes Study.J Clin Endocrinol Metab. 2020 Jan 19;:Authors: Kim C, Younes N, Temprosa M, Edelstein S, Goldberg RB, Araneta MG, Wallia A, Brown A, Darwin C, Ibebuogu U, Pi-Sunyer X, Knowler WC, Diabetes Prevention Program Research GroupAbstract OBJECTIVE:...
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Gamma-glutamyl transferase variability and risk of dementia in diabetes mellitus: a nationwide population-based study.: Related ArticlesGamma-glutamyl transferase variability and risk of dementia in diabetes mellitus: a nationwide population-based study.J Clin Endocrinol Metab. 2020 Jan 19;:Authors: Hong SH, Han K, Park S, Kim SM, Kim NH, Choi KM, Baik SH, Park YG, Yoo HJAbstract CONTEXT: Gamma-glutamyl transferase (GGT) has been associated with oxidative stress and inflammatory reactions....
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Risk Factors for Cardiovascular Disease (CVD) in Adults with Type 1 Diabetes: Findings from Prospective Real-life T1D Exchange Registry.: Related ArticlesRisk Factors for Cardiovascular Disease (CVD) in Adults with Type 1 Diabetes: Findings from Prospective Real-life T1D Exchange Registry.J Clin Endocrinol Metab. 2020 Jan 19;:Authors: Shah VN, Bailey R, Wu M, Foster NC, Pop-Busui R, Katz M, Crandall J, Bacha F, Nadeau K, Libman I, Hiers P, Mizokami-Stout K, DiMeglio LA, Sherr J, Pratley R, Agarwal...
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MiR-204-5p Inhibits Transforming Growth Factor-β1-Induced Proliferation and Extracellular Matrix Production of Airway Smooth Muscle Cells by Regulating Six1 in Asthma.: Related ArticlesMiR-204-5p Inhibits Transforming Growth Factor-β1-Induced Proliferation and Extracellular Matrix Production of Airway Smooth Muscle Cells by Regulating Six1 in Asthma.Int Arch Allergy Immunol. 2020 Jan 17;:1-10Authors: Yang Z, Qu Z, Yi M, Lv Z, Wang Y, Shan Y, Ran N, Liu XAbstract BACKGROUND: Transforming growth...
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Associations between Seven Common Cytokine Gene Polymorphisms and Coronary Artery Disease: Evidence from a Meta-Analysis.: Related ArticlesAssociations between Seven Common Cytokine Gene Polymorphisms and Coronary Artery Disease: Evidence from a Meta-Analysis.Int Arch Allergy Immunol. 2020 Jan 17;:1-10Authors: Yang P, Liu J, Xiao J, Jian H, Chen HAbstract BACKGROUND: Associations of polymorphisms in interferon-gamma (IFNG), interleukin-10 (IL-10), and interleukin-18 (IL-18) with coronary...
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New Insights into CAPNON: A 20-Year Radiologic-Pathologic Study of 37 Cases.: Related ArticlesNew Insights into CAPNON: A 20-Year Radiologic-Pathologic Study of 37 Cases.Histopathology. 2020 Jan 19;:Authors: Ho ML, Eschbacher KL, Paolini MA, Raghunathan AAbstract AIMS: Calcifying pseudoneoplasm of the neuraxis (CAPNON) is a rare entity that can occur anywhere within the central nervous system. At histology, CAPNON has been characterized as a benign, calcified, fibro-osseous lesion with characteristic...
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Clinical outcomes of adults with eosinophilic esophagitis with severe stricture.: Related ArticlesClinical outcomes of adults with eosinophilic esophagitis with severe stricture.Gastrointest Endosc. 2020 Jan 16;:Authors: Kim JP, Weingart G, Hiramoto B, Gregory DL, Gonsalves N, Hirano IAbstract BACKGROUND & AIMS: Eosinophilic esophagitis (EoE) is an inflammatory disease of the esophagus that has been steadily increasing in prevalence over the past three decades. The prognosis of EoE patients...
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The re-emerging pathophysiological role of the cystathionine-β-synthase - hydrogen sulfide system in Down syndrome.: Related ArticlesThe re-emerging pathophysiological role of the cystathionine-β-synthase - hydrogen sulfide system in Down syndrome.FEBS J. 2020 Jan 19;:Authors: Szabo CAbstract Down syndrome (DS) is associated with significant perturbances in many morphological and biochemical features. Cystathionine-β-synthase (CBS) is one of the key mammalian enzymes that is responsible for...
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The mutual interplay of gut microbiota, diet and human disease.: Related ArticlesThe mutual interplay of gut microbiota, diet and human disease.FEBS J. 2020 Jan 19;:Authors: Illiano P, Brambilla R, Parolini CAbstract The intestinal milieu harbours the gut microbiota, consisting of a complex community of bacteria, archaea, fungi, viruses, and protozoans that bring to the host organism an endowment of cells and genes more numerous than its own. In the last ten years, mounting evidence has highlighted...
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Expression of podoplanin correlates with prognosis in nasopharyngeal carcinoma.: Related ArticlesExpression of podoplanin correlates with prognosis in nasopharyngeal carcinoma.Eur Arch Otorhinolaryngol. 2020 Jan 18;:Authors: Wolber P, Schwarz D, Niemczyk M, Drebber U, Klußmann JP, Meyer MAbstract PURPOSE: Podoplanin is a membrane-bound glycoprotein that plays a role in lymphangiogenesis. Several studies suggest a role of podoplanin in head-and-neck cancer. The purpose of the current study...
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Middle ear congenital cholesteatoma: systematic review, meta-analysis and insights on its pathogenesis.: Related ArticlesMiddle ear congenital cholesteatoma: systematic review, meta-analysis and insights on its pathogenesis.Eur Arch Otorhinolaryngol. 2020 Jan 18;:Authors: Gilberto N, Custódio S, Colaço T, Santos R, Sousa P, Escada PAbstract PURPOSE: Congenital cholesteatoma (CC) presents as a white pearl-like lesion behind a normal tympanic membrane (TM), without a history of otorrhea, infection,...
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Reintroduction failure after negative food challenges in adults is common and mainly due to atypical symptoms.: Related ArticlesReintroduction failure after negative food challenges in adults is common and mainly due to atypical symptoms.Clin Exp Allergy. 2020 Jan 19;:Authors: Versluis A, Knulst AC, van Erp FC, Blankestijn MA, Meijer Y, Le TM, van Os-Medendorp HAbstract BACKGROUND: Reintroduction of a food after negative food challenge (FC) faces many obstacles. There are no studies available...
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Relationship between immune parameters during a severe exacerbation in allergic asthmatic children and asthma outcomes in the following year.: Related ArticlesRelationship between immune parameters during a severe exacerbation in allergic asthmatic children and asthma outcomes in the following year.Clin Exp Allergy. 2020 Jan 19;:Authors: Lejeune S, Mordacq C, Drumez E, Brisset S, Pouessel G, Pichavant M, Engelmann I, Béghin L, Decleyre-Badiu I, Neve V, Thumerelle C, Gosset P, Deschildre AAbstract...
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Lung Mechanical Properties Distinguish Children with Asthma with Normal and Diminished Lung Function.: Related ArticlesLung Mechanical Properties Distinguish Children with Asthma with Normal and Diminished Lung Function.Clin Exp Allergy. 2020 Jan 18;:Authors: Comberiati P, Spahn JD, Paull K, Faino A, Cherniack R, Covar RAAbstract BACKGROUND: Children with asthma, even those with severe persistent disease, can have forced expiratory volume in 1 second (FEV1 ) values ≥100% of predicted, while...
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Synthetic Lethal Therapy Based on Targeting the Vulnerability of SWI/SNF Chromatin Remodeling Complex-Deficient Cancers.: Related ArticlesSynthetic Lethal Therapy Based on Targeting the Vulnerability of SWI/SNF Chromatin Remodeling Complex-Deficient Cancers.Cancer Sci. 2020 Jan 19;:Authors: Sasaki M, Ogiwara HAbstract The SWI/SNF chromatin remodeling complex is composed of approximately 15 subunits, and approximately 20% of all cancers carry mutations in the genes encoding these subunits....
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Genetic variants in the folate metabolic pathway genes predict melanoma-specific survival.: Related ArticlesGenetic variants in the folate metabolic pathway genes predict melanoma-specific survival.Br J Dermatol. 2020 Jan 18;:Authors: Dai W, Liu H, Liu Y, Xu X, Qian D, Luo S, Cho E, Zhu D, Amos CI, Fang S, Lee JE, Li X, Nan H, Li C, Wei QAbstract BACKGROUND: Folate metabolism plays an important role in DNA methylation and nucleic acid synthesis and thus may function as a regulatory factor...
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Exploring the impact of paediatric localized scleroderma on health-related quality of life: Focus groups with youth and caregivers.: Related ArticlesExploring the impact of paediatric localized scleroderma on health-related quality of life: Focus groups with youth and caregivers.Br J Dermatol. 2020 Jan 18;:Authors: Zigler CK, Ardalan K, Hernandez A, Caliendo AE, Magee KE, Terry MA, Mann CM, Torok KSAbstractBACKGROUND: Paediatric localized scleroderma (LS) can negatively impact health-related quality...
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Relative Effectiveness of Electroacupuncture and Biofeedback in Treatment of Neck and Upper Back Myofascial Pain: a Randomized Clinical Trial".: Related ArticlesRelative Effectiveness of Electroacupuncture and Biofeedback in Treatment of Neck and Upper Back Myofascial Pain: a Randomized Clinical Trial".Arch Phys Med Rehabil. 2020 Jan 16;:Authors: Eslamian F, Jahanjou F, Dolatkhah N, Pishgahi A, Pirani AAbstract OBJECTIVE: To determine the differences between clinical effects of electro-acupuncture...
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Hypophosphatemia in children treated with ferric carboxymaltose.: Related ArticlesHypophosphatemia in children treated with ferric carboxymaltose.Acta Paediatr. 2020 Jan 18;:Authors: Posod A, Schaefer B, Mueller T, Zoller H, Kiechl-Kohlendorfer UAbstract In adults, iron-induced hypophosphatemia is an increasingly recognized adverse drug reaction of certain high-dose intravenous iron formulations, particularly ferric carboxymaltose (FCM) (1-3). Data in children are sparse, but severe hypophosphatemia...
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Children with home mechanical ventilation - parents' health-related quality of life, family functioning and sleep.: Related ArticlesChildren with home mechanical ventilation - parents' health-related quality of life, family functioning and sleep.Acta Paediatr. 2020 Jan 18;:Authors: Israelsson-Skogsberg Å, Persson C, Markström A, Hedén LAbstract AIM: Children requiring home mechanical ventilation (HMV) have grown in number and complexity. Parents of children with HMV are often responsible...
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IL33 rs1342326 gene variation is associated with allergic rhinitis at school age after infant bronchiolitis.: Related ArticlesIL33 rs1342326 gene variation is associated with allergic rhinitis at school age after infant bronchiolitis.Acta Paediatr. 2020 Jan 18;:Authors: Korppi M, Teräsjärvi J, Lauhkonen E, Huhtala H, Nuolivirta K, He QAbstract AIM: Interleukin (IL)-33, encoded by the IL33 gene, is associated with allergy and asthma. We evaluated IL33 rs1342326 polymorphism in relation to...
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Recommendations on neonatal light environment from the French Neonatal Society.: Related ArticlesRecommendations on neonatal light environment from the French Neonatal Society.Acta Paediatr. 2020 Jan 18;:Authors: Zores C, Kuhn P, Caeymaex L, Group of Reflection, Evaluation of the Environment of Newborns study group of the French Neonatology SocietyAbstract AIM: Hospital light may affect neonatal neurosensory development and the well-being of parents and caregivers. We aimed to issue practical...
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A triple-chamber parenteral nutrition solution was associated with improved protein intake in very low birthweight infants.: Related ArticlesA triple-chamber parenteral nutrition solution was associated with improved protein intake in very low birthweight infants.Acta Paediatr. 2020 Jan 19;:Authors: Immeli L, Mäkelä PM, Leskinen M, Rinta-Koski OP, Sund R, Andersson S, Luukkainen PAbstract AIM: We evaluated the nutrient intakes of very low birthweight (VLBW) infants weighing less than 1500g...
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Anti-epidermal growth factor receptor monoclonal antibody plus palliative chemotherapy as a first-line treatment for recurrent or metastatic nasopharyngeal carcinoma.: Related ArticlesAnti-epidermal growth factor receptor monoclonal antibody plus palliative chemotherapy as a first-line treatment for recurrent or metastatic nasopharyngeal carcinoma.Cancer Med. 2020 Jan 19;:Authors: Chen C, Zhou Y, Zhang X, Fu S, Lin Z, Fang W, Yang Y, Huang Y, Zhao H, Hong S, Zhang LAbstract BACKGROUND: Platinum-based...
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[Outcomes and quality of life evaluation following endoscopic endonasal approach for sinonasal malignancies].: Related Articles[Outcomes and quality of life evaluation following endoscopic endonasal approach for sinonasal malignancies].Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Jan 07;55(1):21-28Authors: Zhang N, Huang Q, Cui SJ, Qiu E, Yang BT, Chen XH, Zhang SR, Li M, Zhou BAbstract Objective: To analyse the outcomes and the prognostic factors of patients with sinonasal malignancies...
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[Reconstruction of orbital floor defect with preserved orbital contents after advanced maxillary sinus cancer resection].: Related Articles[Reconstruction of orbital floor defect with preserved orbital contents after advanced maxillary sinus cancer resection].Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Jan 07;55(1):29-33Authors: Hu HY, Zhang EP, Li B, Cheng XQ, Zhang GL, Shi L, Shi GGAbstract Objective: To analyze the method and effect of reconstruction of the orbital floor defect...
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[A study on the targeted nanoparticles of isosorbide mononitrate on reducing the levels of inflammatory factors in rabbit models of rhinosinusitis].: Related Articles[A study on the targeted nanoparticles of isosorbide mononitrate on reducing the levels of inflammatory factors in rabbit models of rhinosinusitis].Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Jan 07;55(1):40-46Authors: Zhang YQ, Zhao YL, Dong D, Zhang ST, Zhang YAbstract Objective: To investigate the effect of isosorbide...
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[Clinical analysis of 5 cases of dural arteriovenous fistulas complained of pulsatile tinnitus].: Related Articles[Clinical analysis of 5 cases of dural arteriovenous fistulas complained of pulsatile tinnitus].Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Jan 07;55(1):56-59Authors: Jia XD, Bai WX, Geng YX, Wang GK, Ding SG, Liu HJAbstract Objective: The clinical characteristics of dural arteriovenous fistula with pulsatile tinnitus were analyzed to deepen the understanding of the disease....
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Quantitative Metastatic Lymph Node Burden and Survival in Merkel Cell Carcinoma.: Related ArticlesQuantitative Metastatic Lymph Node Burden and Survival in Merkel Cell Carcinoma.J Am Acad Dermatol. 2020 Jan 16;:Authors: Nguyen AT, Luu M, Lu DJ, Hamid O, Mallen-St Clair J, Faries MB, Gharavi NM, Ho AS, Zumsteg ZSAbstract BACKGROUND: Current lymph node (LN) staging for Merkel cell carcinoma (MCC) does not account for number of metastatic LNs, which is a primary driver of survival in multiple...
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A rare case of the recurrent surgery for cribriform-morular variant of papillary thyroid carcinoma.: Related ArticlesA rare case of the recurrent surgery for cribriform-morular variant of papillary thyroid carcinoma.Int J Surg Case Rep. 2019 Dec 06;66:385-389Authors: Enomoto K, Tamagawa S, Kumashiro N, Warigaya K, Takeda S, Gunduz M, Murata SI, Hotomi MAbstract INTRODUCTION: The cribriform-morular variant of papillary thyroid carcinoma (CMV-PTC) is an uncommon subtype of PTC, and it is associated...
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Expression of podoplanin correlates with prognosis in nasopharyngeal carcinoma.: Related ArticlesExpression of podoplanin correlates with prognosis in nasopharyngeal carcinoma.Eur Arch Otorhinolaryngol. 2020 Jan 18;:Authors: Wolber P, Schwarz D, Niemczyk M, Drebber U, Klußmann JP, Meyer MAbstract PURPOSE: Podoplanin is a membrane-bound glycoprotein that plays a role in lymphangiogenesis. Several studies suggest a role of podoplanin in head-and-neck cancer. The purpose of the current study...
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Development of a template tool for facilitating fibula osteotomy in reconstruction of mandibular defects by digital analysis of the human mandible.: Related ArticlesDevelopment of a template tool for facilitating fibula osteotomy in reconstruction of mandibular defects by digital analysis of the human mandible.Clin Oral Investig. 2020 Jan 18;:Authors: Nobis CP, Kesting MR, Wolff KD, Frohwitter G, Rau A, Weitz JAbstractOBJECTIVES: Mandibular reconstruction after segmental mandibulectomy can be challenging...
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