Δευτέρα, 22 Φεβρουαρίου 2016

Early- and late-latency gamma auditory steady-state response in schizophrenia during closed eyes: does hallucination status matter?

The auditory steady-state response (ASSR) - a response to periodic stimulation - has been proposed to serve as one of the biological markers of schizophrenia, being consistently impaired in the disorder (O'Donnell et al., 2013). The response to gamma range stimulation has been employed both to evaluate global synchronization of neural activity with the external environment (Light et al., 2006; Koenig et al., 2012; Tada et al., 2014) and the integrity of auditory circuits (Teale et al., 2003; Brenner et al., 2009; Spencer et al., 2009; Hamm et al., 2011).

from Physiology via xlomafota13 on Inoreader http://ift.tt/1TBIHCE
via IFTTT

RETROGRADE INTUBATION WITH SUCTION CATHETER: A CASE REPORT

2016-02-22T18-20-48Z
Source: Journal of Contemporary Medicine
AHMET SELİM ÖZKAN, AYTAÇ YÜCEL, MUSTAFA SAİD AYDOĞAN, MUSTAFA KADIOĞLU, TÜRKAN TOĞAL.
Tracheal intubation has become a necessary part in the management of general anesthesia for surgical patient. Anesthetic management of difficult intubation and difficult ventilation will encounter are the major complications and most common cause of mortality and morbidity related to anesthesia. We aimed to present a case of retrograde intubation with suction catheter connected to an electrical burn injury to the trachea.


from Scope via xlomafota13 on Inoreader http://ift.tt/1QWVMAr
via IFTTT

Major Depressive Disorder' Definition, Etiology and Epidemiology: A Review

2016-02-22T18-20-48Z
Source: Journal of Contemporary Medicine
Fatmagül Helvacı Çelik, Çiçek Hocaoğlu.
Depression is one of the most common psychiatric disorders influencing the all population. Untreated depression may lead to early death and worsening in general health. Depression has several clinically distinct subtypes which are sometimes difficult to diagnose. Diagnosis and treatment of these disorders are of concern to physicians other than psychiatrists, because of their effect on course and prognosis of general medical diseases. This is a concise and up to date overview of the epidemiology,etiology physiopathology and diagnosis of major depressive disorder.


from Scope via xlomafota13 on Inoreader http://ift.tt/1QdlAMr
via IFTTT

Acute Renal Failure Due To Ethyleneglycol Poisoning

2016-02-22T18-20-48Z
Source: Journal of Contemporary Medicine
İhsan Ateş, Nihal Ozkayar, Nergiz Bayrakci, Fatih Dede.
Ethylene glycol is a colorless, odorless, sweet, water-soluble substance from the group of dihydric alcohols. As a result of taking ethylene-containing material for suicide purpose or as an accident, serious metabolic acidosis, central nervous system depression and oliguric acute renal failure occur. Early diagnosis and treatment can reduce mortality at a significant level. We present a case with severe metabolic acidosis, coma and acute renal failure due to ethylene glycol intoxication after drinking antifreeze accidentally.


from Scope via xlomafota13 on Inoreader http://ift.tt/1QWVMk9
via IFTTT

Neutrophil-lymphocyte ratio and platelet-lymphocyte ratio on the prediction of methotrexate treatment success in tubal ectopic pregnancy

2016-02-22T18-20-48Z
Source: Journal of Contemporary Medicine
Hatice Yılmaz Doğru, Çiğdem Kunt İşgüder, Asker Zeki Özsoy, İlhan Bahri Delibas, Bülent Cakmak, Akgul Arici.
Objective A %2 of all pregnancies composed of ectopic pregnancy, further more than 95% of cases localized on the fallopian tubes. The aim of this study is to assess the success of metotrexate treatment on tubal pregnancy, and the relation between the neutrophil-lymphocyte ratio and thrombocyte-lymphocyte ratio, and tubal ectopic pregnancy rupture. Materials and Methods This retrospective study was conducted in Gaziosmanpasa University, Department of Obstetrics and Gynecology between 2012 and 2014. Patients with a diagnosis of tubal ectopic pregnancy whose admitted to the Department of Obstetrics and Gynecology were enrolled in the study. The data was analyzed using the Statistical Package for Social Sciences (SPSS) software version 20 (SPSS Inc., Chicago, IL). A two-tailed p value


from Scope via xlomafota13 on Inoreader http://ift.tt/1QdlAw5
via IFTTT

THE EVALUATION OF THE PATIENTS OF THOSE OPERATED DUE TO THE OVARY CYST: RETROSPECTIVE ANALYSIS

2016-02-22T18-20-48Z
Source: Journal of Contemporary Medicine
Hatice Yılmaz Doğru, Asker Zeki Özsoy, Akgul Arici, Selim Gulucu, Fazlı Demirtürk.
Aim: Ovarian cyst, those can be seen in all ages of women, is a common gynecologic problem. The present study is aimed to retrospectively evaluate the clinical features of the operated patients due to ovarian cyst. Materials and Methods: A total of 50 cases with a diagnosis of ovarian mass whose admitted or referred to the Gaziosmanpasa University, Medical Faculty, Gynecology and Obstetrics outpatient unit with any complaint were retrospectively evaluated and included into this study. Results: The mean age of the patients were 33.75±11.70. The most complaint was found as pelvic pain by 79%. The hospital stay of the cases underwent laparoscopic surgery (3.62±0.57 days) was significantly lower than the laparotomy (5.48±2.58 days, p = 0.000392). A 57.2% of the cases were non-neoplastic tumor, where 47.3% were neoplastic. Conclusion: It is suggested that the physical examination of adnexial mass is the most important factor affecting the choice of the surgical type.


from Scope via xlomafota13 on Inoreader http://ift.tt/1QWVMjW
via IFTTT

THE EVALUATE HISTOPATHOLOGICAL RESULTS OF PATIENTS WHO UNDERWENT HYSTERECTOMY DUE TO POSTMENOPAUSAL BLEEDING

2016-02-22T18-20-48Z
Source: Journal of Contemporary Medicine
Mine Genç, Esin Kasap, Serkan güçlü.
Aims: To evaluate histopathological results in hysterectomy materials of patients with postmenopausal bleeding in our clinic. Materials-Methods: This study is conducted by retrospective assessment of 72 patients who underwent hysterectomy due to postmenopausal bleeding between April 2007 and June 2013 in our clinic. Age, parite, body mass index of patients and, histopathological examination of the uterus after hysterectomy were assessed. Results: Mean age of the subjects was 57.1 ±7.9. Histopathologic diagnoses were as follows: endometrial polyp (25%), endometrial hyperplasia (20.9%), proliferative endometrium (20.9%), myoma uteri(16.6%), atrophic endometrium (6.9%), endometrium cancer(9.7%). Conclusion: The most common endometrial pathologia in patients who underwent hysterectomy due to postmenopausal bleeding was endometrial polyp. Although the most common reason of postmenopausal bleeding is atrophic endometrium, atrophic endometrium is detected in the histopathological examination as a few. The reason is that the first option treatment can be medical treatment and observation.


from Scope via xlomafota13 on Inoreader http://ift.tt/20RO9R7
via IFTTT

EFFECT OF ANKLE BRACING ON RECURRENCE OF ANKLE SPRAIN IN MALE FOOTBALL PLAYERS

2016-02-22T17-47-59Z
Source: International Journal of Therapies and Rehabilitation Research
Abdelrazek Youssef Bayomi.
Abstract Background and purpose of study: Ankle injuries are among the most common sports-related injuries, accounting for up to 20% of injuries. Ankle sprains account for 3373% of ankle injuries. The aim of this study was to evaluate the effectiveness of ankle bracing in preventing recurrences of ankle sprains, especially in male soccer players. Methods: A randomized controlled study was conducted in Prince Sattam bin Abdul Aziz University. 30 football players in university football team aged 18 to 23 years were obtained between November 2014 and May 2015, 15 were randomly selected to the study group (Ankle bracing group) and 15 to the control group (Untreated group without bracing). Subjects: All football players who had suffered from past history of ankle sprain (30 players) were identified as subjects. Measurements: Each previously injured ankle (n = 30) was considered as a case for the analysis. Ankles that had a past sprain received one of two groups; ankle bracing group (n = 15) and untreated group (n = 15). Results: There was significant difference between intervention group and control group. Ankle sprain recurrence frequency was 0% and 27% for the braced and control group, respectively. The recurrence incidence for the braced group was significantly fewer than that of the control group. Conclusions: It was concluded that this study suggest that ankle bracing is effective in preventing the incidence of ankle sprains in male football players with a past history of ankle sprains.


from Scope via xlomafota13 on Inoreader http://ift.tt/20RvHYN
via IFTTT

FirstPass by FirstWatch Informational Video

FirstPass®, from the creators of FirstWatch®, can review the entire patient experience from the time 911 is called to delivery at the hospital. Improving the quality, collection and analysis of data improves billing and financial recovery.

from EMS via xlomafota13 on Inoreader http://ift.tt/1TBc9c8
via IFTTT

Field Paramedic - Williamson County EMS

Provides exceptional pre-hospital clinical medicine based on the EMS Department's Scope of Care. Maintains and troubleshoots medical equipment. Maintains equipment and vehicles. ESSENTIAL DUTIES: Functions independently, once credentialed by the Medical Director. Ability to assess emergency scenes. Manages medical and trauma patients; directs co-workers, first responders, and bystanders. Utilizes electronic ...

from EMS via xlomafota13 on Inoreader http://ift.tt/1Rjkz4A
via IFTTT

FirstPass by FirstWatch Informational Video

FirstPass®, from the creators of FirstWatch®, can review the entire patient experience from the time 911 is called to delivery at the hospital. Improving the quality, collection and analysis of data improves billing and financial recovery.

from EMS via xlomafota13 on Inoreader http://ift.tt/1TBc9c8
via IFTTT

FirstPass by FirstWatch Informational Video

FirstPass®, from the creators of FirstWatch®, can review the entire patient experience from the time 911 is called to delivery at the hospital. Improving the quality, collection and analysis of data improves billing and financial recovery.

from EMS via xlomafota13 on Inoreader http://ift.tt/1TBc9c8
via IFTTT

FirstPass by FirstWatch Informational Video

FirstPass®, from the creators of FirstWatch®, can review the entire patient experience from the time 911 is called to delivery at the hospital. Improving the quality, collection and analysis of data improves billing and financial recovery.

from EMS via xlomafota13 on Inoreader http://ift.tt/1TBc9c8
via IFTTT

Dispatch audio: Gunman's rampage

Responders treated eight gunshot victims spread out over several miles

from EMS via xlomafota13 on Inoreader http://ift.tt/1oYFKQ7
via IFTTT

Carbon monoxide kills family of 6 in Mich.

Michigan police say a family of six, including a two-year-old child, died from carbon monoxide poisoning in their home.

from EMS via xlomafota13 on Inoreader http://ift.tt/1UiLgcd
via IFTTT

Wound packing and soak through procedures



from EMS via xlomafota13 on Inoreader http://ift.tt/1PTbbEa
via IFTTT

Dispatch audio: Gunman's rampage

Responders treated eight gunshot victims spread out over several miles

from EMS via xlomafota13 on Inoreader http://ift.tt/1oYFKQ7
via IFTTT

Carbon monoxide kills family of 6 in Mich.

Michigan police say a family of six, including a two-year-old child, died from carbon monoxide poisoning in their home.

from EMS via xlomafota13 on Inoreader http://ift.tt/1UiLgcd
via IFTTT

Wound packing and soak through procedures



from EMS via xlomafota13 on Inoreader http://ift.tt/1PTbbEa
via IFTTT

Dispatch audio: Gunman's rampage

Responders treated eight gunshot victims spread out over several miles

from EMS via xlomafota13 on Inoreader http://ift.tt/1oYFKQ7
via IFTTT

Carbon monoxide kills family of 6 in Mich.

Michigan police say a family of six, including a two-year-old child, died from carbon monoxide poisoning in their home.

from EMS via xlomafota13 on Inoreader http://ift.tt/1UiLgcd
via IFTTT

Wound packing and soak through procedures



from EMS via xlomafota13 on Inoreader http://ift.tt/1PTbbEa
via IFTTT

Police chase ends when driver strikes ambulance

Police release dash cam video showing a crash that ended a police chase.

from EMS via xlomafota13 on Inoreader http://ift.tt/1XICXGF
via IFTTT

Firefighter/Paramedic - Snohomish County Fire District #4

SNOHOMISH COUNTY FIRE DISTRICT 4 1525 Ave D SNOHOMISH, WASHINGTON 98290 Updated: February 22, 2016 Classification: Firefighter/Paramedic Snohomish County Fire District #4 is currently developing an eligibility list for the position of Firefighter/Paramedic to hire from as needed in 2016. This posting will close on March 18, 2016. Testing is conducted through National Testing Network (NTN). Salary Information: ...

from EMS via xlomafota13 on Inoreader http://ift.tt/1XIuVxr
via IFTTT

Police chase ends when driver strikes ambulance

Police release dash cam video showing a crash that ended a police chase.

from EMS via xlomafota13 on Inoreader http://ift.tt/1XICXGF
via IFTTT

Police chase ends when driver strikes ambulance

Police release dash cam video showing a crash that ended a police chase.

from EMS via xlomafota13 on Inoreader http://ift.tt/1XICXGF
via IFTTT

Police chase ends when driver strikes ambulance

Police release dash cam video showing a crash that ended a police chase.

from EMS via xlomafota13 on Inoreader http://ift.tt/1XICXGF
via IFTTT

College students get ambulance simulator for hands-on training

The simulator looks like a real ambulance with flashing emergency lights and standard equipment; students practice procedures on lifelike mannequins

from EMS via xlomafota13 on Inoreader http://ift.tt/1QxHagS
via IFTTT

Maximillian Muenke, Paul Kruszka, Craig A. Sable, John W. Belmont (eds): Congenital heart disease molecular genetics, principles of diagnosis and treatment



from Genetics via xlomafota13 on Inoreader http://ift.tt/1RiEq3G
via IFTTT

Gene co-expression analysis identifies brain regions and cell types involved in migraine pathophysiology: a GWAS-based study using the Allen Human Brain Atlas

Abstract

Migraine is a common disabling neurovascular brain disorder typically characterised by attacks of severe headache and associated with autonomic and neurological symptoms. Migraine is caused by an interplay of genetic and environmental factors. Genome-wide association studies (GWAS) have identified over a dozen genetic loci associated with migraine. Here, we integrated migraine GWAS data with high-resolution spatial gene expression data of normal adult brains from the Allen Human Brain Atlas to identify specific brain regions and molecular pathways that are possibly involved in migraine pathophysiology. To this end, we used two complementary methods. In GWAS data from 23,285 migraine cases and 95,425 controls, we first studied modules of co-expressed genes that were calculated based on human brain expression data for enrichment of genes that showed association with migraine. Enrichment of a migraine GWAS signal was found for five modules that suggest involvement in migraine pathophysiology of: (i) neurotransmission, protein catabolism and mitochondria in the cortex; (ii) transcription regulation in the cortex and cerebellum; and (iii) oligodendrocytes and mitochondria in subcortical areas. Second, we used the high-confidence genes from the migraine GWAS as a basis to construct local migraine-related co-expression gene networks. Signatures of all brain regions and pathways that were prominent in the first method also surfaced in the second method, thus providing support that these brain regions and pathways are indeed involved in migraine pathophysiology.



from Genetics via xlomafota13 on Inoreader http://ift.tt/1QceZSl
via IFTTT

Association of Acculturation and Health Literacy with Prevalent Dysglycemia and Diabetes Control Among Latinos in the Boston Area Community Health (BACH) Survey

Abstract

This study assessed the effect of acculturation on type 2 diabetes and whether health literacy may mediate this association. The Boston Area Community Health cohort is a multi-stage stratified random sample of adults from Boston including 744 Latinos. We defined dysglycemia as a HbA1c ≥5.7 %. Multivariable analyses examined the associations between acculturation and health literacy adjusting for demographic and clinical variables. Similar analyses were performed among participants with HbA1c ≥7.0 % to assess the association between acculturation and diabetes control. Among an insured primarily foreign born Spanish speaking Latino population, with a long residence period in the US and good healthcare utilization, higher levels of acculturation were not associated with dysglycemia. Lower levels of acculturation were associated with worse diabetes control. Health literacy level did not modify these associations. Elucidating the components of heterogeneity among Latinos will be essential for understanding the influence of acculturation on diabetes.



from Health via xlomafota13 on Inoreader http://ift.tt/1oY7oN7
via IFTTT

Capnography best practices to improve patient handoff reports

Use these documentation and handoff tips to communicate important patient information to ED and ICU staff unfamiliar with capnography

from EMS via xlomafota13 on Inoreader http://ift.tt/1WDWt5K
via IFTTT

How an Ariz. fire department reduced medication errors

Training, including pediatric-specific training, reduced self-reported medication errors in a major fire-based EMS system

from EMS via xlomafota13 on Inoreader http://ift.tt/1KEnsO3
via IFTTT

Perspectives on current resuscitation guidelines, techniques

EMS medical directors discuss pediatric and pregnant patient resuscitation, the use of active compression devices and head-elevated CPR at Gathering of Eagles

from EMS via xlomafota13 on Inoreader http://ift.tt/1WDWreg
via IFTTT

How an Ariz. fire department reduced medication errors

DALLAS — Medication error prevention training, with a specific focus on reducing pediatric drug dosage errors helped a major fire-based EMS system significantly reduce drug administration errors.

The results of an eight year project, started in 2008 and conducted at the Phoenix Fire Department, were presented by John Gallagher, MD at the 2016 Gathering of Eagles XVIII EMS State of the Science program. The project showed the effectiveness of reporting and training to reduce medication errors.

A medication error is defined as any preventable error involving medication that may cause injury or harm to the patient. At the start of the project, 10 percent of paramedics anonymously, self-reported a medication error.

By 2014, the rate of reported errors declined to 2 percent. General education about medication administration and error prevention cut the error rate in half. Many studies, cited by Gallagher, have shown higher rates of errors in pediatric patients and the need for training specific to pediatric medication error prevention. Additional pediatric specific training in 2011 halved the error rate.

Memorable quotes regarding prevention of EMS medication errors

"All of the 2015 errors involved wrong drug dosages. We have eliminated wrong drug errors."
John Gallagher, MD

"Why would you want to be in a hurry to give the patient the wrong medication" Slow down, talk to your partner."
John Gallagher, MD

Key takeaways to prevent EMS medication errors
Here are key takeaways for medical directors and EMS field providers from Gallagher's presentation.

  • Medication administration and error prevention training programs reduce error rates.
  • Pediatric specific medication error prevention, especially avoiding epinephrine dosage errors, is also needed.
  • Job aids, charts, apps or cards such as the PFD Peds Code Card for epinephrine administration dosing can help prevent drug errors.
  • Regular, online and face-to-face, training is important for all drugs and even more important for new drugs.
  • Allow, encourage and facilitate non-punitive error reporting in your EMS system.

Visit GatheringofEagles.us to view the presenter's slides.



from EMS via xlomafota13 on Inoreader http://ift.tt/1QtBG0c
via IFTTT

Changes in intracortical inhibition and clinical symptoms after STN-DBS in Parkinson’s disease

S13882457.gif

Publication date: April 2016
Source:Clinical Neurophysiology, Volume 127, Issue 4
Author(s): Masahito Kobayashi, Takayuki Ohira, Ban Mihara, Takamitsu Fujimaki
ObjectivesTo examine effects of subthalamic nucleus deep brain stimulation (STN-DBS) on intracortical inhibition in Parkinson's disease (PD) and the correlation between intracortical inhibition and clinical symptoms after alteration of STN-DBS status.MethodsNine PD patients treated by STN-DBS were compared with eight age-matched controls. Antiparkinsonian medication was withdrawn 12h before the study. Short-interval intracortical inhibition (SICI) with a 3-ms interval and silent period (SP) were examined using transcranial magnetic stimulation. SP duration, SICI and motor symptoms (rigidity and tremor) were evaluated with STN-DBS ON, and over 120min during STN-DBS OFF.ResultsEven during STN-DBS, PD patients showed a shortened SP and reduced SICI relative to normal controls. SICI decreased further throughout STN-DBS OFF, resulting in facilitation rather than inhibition; SP shortened only after 120min STN-DBS OFF. Both rigidity and tremor worsened throughout STN-DBS OFF, with a time course similar to SICI.ConclusionEven during STN-DBS, both SICI and SP in PD patients remain impaired without medication. Changes in SICI, but not SP, show a time course similar to those of motor symptoms.SignificanceThe dissimilarity of SICI and SP changes suggests differences in mediation of inhibitory mechanisms and/or superimposition of exaggerated intracortical facilitation on SICI.



from Physiology via xlomafota13 on Inoreader http://ift.tt/1LCvmCw
via IFTTT

SD goes high tech with new 911 system

The service will link all 911 dispatch centers in the state and will improve location accuracy of 911 calls

from EMS via xlomafota13 on Inoreader http://ift.tt/1WDD4lD
via IFTTT

A study of diaphyseal nutrient foramina in human femur

2016-02-22T06-20-27Z
Source: International Journal of Research in Medical Sciences
Roopam Kumar Gupta, Aruna Kumari Gupta.
Background: The external opening of the nutrient canal in a bone is the nutrient foramen (NF). It is clinically important to have an understanding of the location, number, direction and caliber of diaphyseal nutrient foramina in femur, especially in orthopedic surgical procedures. Here we study the diaphyseal nutrient foramina of femur in detail. Methods: This study was conducted on 312, (154 right and 158 left), macerated specimens of adult human femur. All the important parameters were studied using osteometric board, vernier calipers and other precision measuring instruments. Results: The mean number of nutrient foramina per femur bone was 1.64 and mean distance of NF from upper end of femur was 19.48 cms. The foraminal index obtained was 45.01%. The most common location of NF was on the medial lip of linea aspera (40.9%). 44.6% femur had only one NF, while 49.4% had two NF, 3.8% femur had three NFs and 2.24% femur had four NFs. 50.48% of NFs were of big size caliber, 26.6% were of medium size and 22.8% were of small caliber. So 77.1% NFs in femur were dominant foramina. In all the bones studied the direction of the nutrient foramina was always directed upwards. Conclusions: The findings of this study on nutrient foramina adds to the information from studies in the past by other authors but the importance of this study lies in the large sample size and the detailed study of caliber of the nutrient foramen for the first time.


from Scope via xlomafota13 on Inoreader http://ift.tt/1TvfNTp
via IFTTT

Prevalence of Obesity and Physical Inactivity in Individuals who Applied to the Family Medicine Center: the Case of Elaziğ [Aile Hekimliği Birimine Başvuran Bireylerde Obezite Sikliği Ve Fiziksel Inaktivite: Elaziğ Örneği]

2016-02-22T05-53-11Z
Source: Medicine Science | International Medical Journal
Bircan Ulas, Fatos Uncu, Pinar Soylar.
The aim of this study was to determine the prevalence of obesity and physical inactivity in individuals who applied to the Family Medicine Centers. This descriptive study was carried out on 739 subjects (subjects included 473 men and 266 women), who agreed to participate in this study, aged 20 and older, who applied to Family Medicine Centers in Elazig in the period February 2015 for diagnostic or therapeutic purposes. Data were collected by the interviewers with the questionnaire method. Obesity was assessed according to Body Mass Index BMI (BMI ≥ 30). Participants were classified as inactive and active. Participants who comply with physical activity recommendations (150 minutes per week, 5 days a week for 30 minutes moderate exercise) were classified as active. Data were analyzed by using chi-square, variance analysis and t test. The level of significance was accepted as


from Scope via xlomafota13 on Inoreader http://ift.tt/1TAb4RR
via IFTTT

Socioeconomic, bio-demographic and health/behavioral determinants of neonatal mortality in Nigeria: a multilevel analysis of 2013 demographic and health survey

2016-02-22T05-22-45Z
Source: International Journal of Contemporary Pediatrics
Emmanuel O. Adewuyi, Yun Zhao, Reeta Lamichhane.
Background: Nigeria ranks as one of the countries in the world with considerable burden of neonatal mortality. This study aims to investigate the association of socioeconomic, bio-demographic and health/behavioural factors with neonatal mortality in the country using the most current available evidence. Methods: The 2013 Nigeria demographic and health survey (NDHS) dataset was analyzed. Multiple logistic regression analysis was applied to identify determinants associated with neonatal mortality. The role of breastfeeding was examined by conducting analyses with and without adjustment for breastfeeding status. Complex sample analysis was used to control for the complex sampling design used in NDHS. Results: Neonatal mortality rate (NMR) stood at 33 deaths per 1000 live births. With or without adjustment for breastfeeding status, bio-demographic factors maternal marital status, rural-urban residence, birth size, gender of child, birth interval and maternal body mass index (BMI) were predictive of neonatal mortality. Maternal age and ethnicity became additional bio-demographic predictors after adjusting for breastfeeding status. Maternal literacy (socioeconomic factor) and mode of delivery (health/behavioral factor) were significant predictors only when breastfeeding status was not adjusted for. Conclusions: Bio-demographic factors formed the bulk of predictors of neonatal mortality in Nigeria. The effect of socioeconomic and bio-demographic factors disappeared when breastfeeding status was adjusted for. Intervention programs would need to prioritize the identified predictors for an accelerated reduction of neonatal mortality in Nigeria.


from Scope via xlomafota13 on Inoreader http://ift.tt/1Q5kjDG
via IFTTT

Clinical study of ventilator associated pneumonia in a tertiary care centre

2016-02-22T05-22-45Z
Source: International Journal of Contemporary Pediatrics
Vedavathy S., Sangamesh.
Background: Ventilator associated pneumonia (VAP) remains to be the commonest cause of hospital morbidity and mortality in spite of advances in diagnostic techniques and management. VAP refers to bacterial pneumonia developing in patients who have been receiving mechanical ventilation for at least 48 hours. It is the commonest complication associated with mechanical ventilation. The objectives were to know the incidence and outcome of VAP in a tertiary care centre at Indira Gandhi Institute of child health (IGICH) and to identify the probable risk factors for ventilator associated pneumonia (VAP) and to identify the most common pathogenic bacteria causing VAP. Methods: This is a prospective study of children mechanically ventilated in the pediatric intensive care unit of Indira Gandhi Institute of Child Health. Children between the age group of >1month to


from Scope via xlomafota13 on Inoreader http://ift.tt/1KDEI62
via IFTTT

Recurrent giant cell fibroblastoma: Malignancy predisposition in Kabuki syndrome revisited

Kabuki syndrome is a genetic condition characterized by distinctive facial phenotype, mental retardation, and internal organ malformations. Mutations of the epigenetic genes KMT2D and KDM6A cause dysregulation of certain developmental genes and account for the multiple congenital anomalies of the syndrome. Eight cases of malignancies have been reported in young patients with Kabuki syndrome although a causative association to the syndrome has not been established. We report a case of a 12-year-old girl with Kabuki syndrome who developed a tumor on the right side of her neck. A relapsing tumor 19 months after initial excision, proved to be giant cell fibroblastoma. Τhis is the first report of giant cell fibroblastoma -a rare tumor of childhood- in a patient with Kabuki syndrome. © 2016 Wiley Periodicals, Inc.



from Genetics via xlomafota13 on Inoreader http://ift.tt/21kxBDA
via IFTTT

Opportunities for improvement in the care of patients hospitalized for inflammatory bowel disease-related colitis

Digestive Diseases and Sciences

from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1QbjCMx
via IFTTT

Daclatasvir combined with sofosbuvir or simeprevir in liver transplant recipients with severe recurrent hepatitis C infection

Liver Transplantation

from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1QUBrMm
via IFTTT

Clinical characteristics and risk factors for the development of postoperative hepatic steatosis after total pancreatectomy

Pancreas

from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1QbjEE8
via IFTTT

Determinants of early mortality among 37,568 patients with colon cancer who participated in 25 clinical trials from the adjuvant colon cancer endpoints database

Journal of Clinical Oncology

from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1QUBrvM
via IFTTT

Associations of microbiota and toll-like receptor signaling pathway in esophageal adenocarcinoma

BMC Cancer

from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1QbjCvX
via IFTTT

Impact of insulin-like growth factor-1 receptor and amphiregulin expression on survival in patients with stage II/III gastric cancer enrolled in the Adjuvant Chemotherapy Trial of S-1 for Gastric Cancer

Gastric Cancer

from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1QUBsj6
via IFTTT

Modified CLIP with objective liver reserve assessment retains prognosis prediction for patients with advanced hepatocellular carcinoma

Journal of Gastroenterology and Hepatology

from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1QbjEnA
via IFTTT

Is celiac disease an etiological factor in children with migraine?

Journal of Child Neurology

from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1QUBp6X
via IFTTT

Physiology of intestinal absorption and secretion

Best Practice & Research Clinical Gastroenterology

from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1QbjE7e
via IFTTT

Chemoradiotherapy with FOLFOX plus cetuximab in locally advanced oesophageal cancer: The GERCOR phase II trial ERaFOX

European Journal of Cancer

from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1QUBoQt
via IFTTT

Analysis of Helicobacter pylori genotypes in clinical gastric wash samples

Tumor Biology

from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1QbjBZ8
via IFTTT

The features of mucosa-associated microbiota in primary sclerosing cholangitis

Alimentary Pharmacology and Therapeutics

from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1QUBoQp
via IFTTT

Statin use is associated with reduced risk of colorectal cancer in patients with inflammatory bowel diseases

Clinical Gastroenterology and Hepatology

from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1QbjBIu
via IFTTT

Helicobacter-negative gastritis: Polymerase chain reaction for Helicobacter DNA is a valuable tool to elucidate the diagnosis

Alimentary Pharmacology and Therapeutics

from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1QUBqrB
via IFTTT

Clinicopathologic and prognostic associations of KRAS and BRAF mutations in small intestinal adenocarcinoma

Modern Pathology

from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1QbjBbn
via IFTTT

Molecular characterization, antimicrobial resistance and Caco-2 cell invasion potential of Campylobacter jejuni/coli from young children with diarrhea

The Pediatric Infectious Disease Journal

from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1QUBojt
via IFTTT

Prosthetic treatment outcome in patients with severe hypodontia: a systematic review

Summary

Severe hypodontia (≥6 missing teeth) is associated with aesthetic and functional problems. Its presentation is heterogenic, and a variety of treatment modalities are used resulting in different treatment outcomes. As there is currently no standard treatment approach for patients with severe hypodontia, the literature was systematically reviewed with the focus on treatment outcomes. Medline, Embase and The Cochrane Central Register of Controlled Trials were searched (last search 24 August 2015). This was completed with a manual search of the reference lists of the selected studies. To be included, studies had to describe dental treatment outcome measure(s) in patients with severe hypodontia; there were no language restrictions. The methodological quality was assessed using MINORS criteria. Twenty-one studies were eligible, but the diversity in type and quality did not allow for a meta-analysis; seventeen studies had a retrospective design; sixteen studies described the results of implant treatment. Treatment with (partial) dentures, orthodontics, fixed crowns or bridges was sparsely presented in the eligible studies. Implant survival, the most frequently reported treatment outcome, ranging from 35·7% to 98·7%, was influenced by 'location' and 'bone volume'. The results of implant treatment in severe hypodontia patients are promising, but due to its heterogenic presentation, its low prevalence and the poor quality of the studies, evidence-based decision-making in the treatment of severe hypodontia is not yet feasible, thus prompting further research.



from Rehabilitation via xlomafota13 on Inoreader http://ift.tt/1Optmx2
via IFTTT

Characteristics of anti Hepatitis C Virus antibody positive patients in a hospital setting in Douala, Cameroon

International Journal of Infectious Diseases

from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1QbjAV1
via IFTTT

New drugs for the treatment of complicated intra-abdominal infections in the era of increasing antimicrobial resistance

International Journal of Antimicrobial Agents

from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1QUBpUJ
via IFTTT

Extra-hepatic replication and infection of hepatitis E virus in neuronal-derived cells

Journal of Viral Hepatitis

from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1QbjAUQ
via IFTTT

Meta-analysis: The diagnostic efficacy of chromoendoscopy for early gastric cancer and premalignant gastric lesions

Journal of Gastroenterology and Hepatology

from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1L56kAQ
via IFTTT

Nematicidal and antimicrobial activities of methanol extracts of seventeen plants, of importance in ethnopharmacology, obtained from the Arabian Peninsula

2016-02-21T23-22-00Z
Source: Journal of Intercultural Ethnopharmacology
Adel Al-Marby, Chukwunonso ECC Ejike, Muhammad Jawad Nasim, Nasser A Awadh-Ali, Rwaida A Al-badani, Ghanem MA Alghamdi, Claus Jacob.
Aim/Background: The development of resistance to synthetic drugs by target organism is a major challenge facing medicine, yet locked within plants are phytochemicals used in herbal medicine (especially in the Arabian Peninsula) that may find application in this regard. In pursuit of unlocking these hidden treasures the methanol extracts of leaves, aerial parts, fruits and resins of seventeen plants used in the Arabian Peninsula were screened for antimicrobial activities. Methods: The nematicidal, antibacterial and antifungal activities using appropriate assays. Steinernema feltiae, Staphylococcus carnosus, Escherichia coli and Saccharomyces cerevisiae were used as test organisms. Concentrations of the extracts ranging from 0.5 to 20 mg/ml were tested and appropriate statistical tests performed on the data generated. Results: The results show that extracts from S. incanum, C. murale, C. myrrha, A. nobilis and A. biebersteinii were the most active, and had very high activities against two or more of the test organisms at low concentrations. Extracts of the leaves of S. incanum and resins of F. asafoetida were the most active nematicides, with significant activity at 0.5 mg/ml. Extracts of C. myrrha and C. murale had the most active antibacterial activity with inhibition zones of 12-15 mm and minimum inhibitory concentrations (MICs) of 2.5 mg/ml for both bacteria. Extracts of the leaves of A. biebersteinii were the most active fungicide, giving an MIC of 1.5 mg/ml. Conclusion: The results validate the use of these plants in ethnopharmacology, and open new vistas of opportunities for the development of cheap but effective agents that may be useful against infectious diseases.


from Scope via xlomafota13 on Inoreader http://ift.tt/1LBRz3r
via IFTTT

Antidiabetic and Antioxidant Effect of Cinnamon in poorly Controlled Type-2 Diabetic Iraqi Patients: A Randomized, Placebo-Controlled Clinical Trial

2016-02-21T23-22-00Z
Source: Journal of Intercultural Ethnopharmacology
Ahmed Salih Sahib.
Abstract Aim: To determine the effect of cinnamon on fasting blood glucose, HbA1c, and oxidative stress markers in poorly controlled type 2 diabetes. Method: 25 type 2 diabetic patients of both sexes, aged 49.1  6.0, treated only with hypoglycemic agent sulfonylurea (glibenclamide) were randomly assigned to receive either 1g of cinnamon or placebo daily for 12 weeks. Results: A highly significant (P≤0.001) reduction (10.12%) of fasting blood glucose level after 6 and 12 weeks of treatment 10.12% and 17.4% respectively compared to baseline value and to placebo group at corresponding duration. Meanwhile, the value of glycosylated hemoglobin reduced in cinnamon treated group by (2.625%) and (8.25%) after six and 12 weeks respectively, although this reduction was non-significant compared to baseline value. Concerning the oxidative stress markers, the level of serum glutathione showed highly significant (P≤0.001) elevation after 12 weeks as compared to baseline value and placebo group at corresponding duration, malondialdehyde serum level decreased after treatment of diabetic patients with cinnamon resulted in highly significant (P≤0.001) reduction after six and 12 weeks compared to placebo group, but when compared to baseline value, there is a (15%) reduction only after 12 weeks of treatment which was considered highly significant (P≤0.001) change, Finally, administration of cinnamon to diabetic patients for 12 weeks resulted in significant (P≤0.05) elevation of SOD level. Conclusion: Intake of 1g of cinnamon for 12 weeks reduces fasting blood glucose and glycosylated hemoglobin among poorly controlled type 2 diabetes patients, as well as, there is improvement in the oxidative stress markers, indicating the beneficial effect of adjuvant cinnamon as antidiabetic and antioxidant along with conventional medications to treat poorly controlled type 2 diabetes mellitus.


from Scope via xlomafota13 on Inoreader http://ift.tt/24m9JSo
via IFTTT