Effects of Roux-en-Y gastric bypass surgery on postprandial fructose metabolism

Obesity

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Modelling the impact of deferring HCV treatment on liver-related complications in HIV coinfected men who have sex with men

Journal of Hepatology

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[18F]FPRGD2 PET/CT imaging of integrin ?v?3 levels in patients with locally advanced rectal carcinoma

European Journal of Nuclear Medicine & Molecular Imaging

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Prognostic role of 25-hydroxyvitamin D in patients with liver metastases from colorectal cancer treated with radiofrequency ablation

Journal of Gastroenterology and Hepatology

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Histone deacetylase 2 regulates doxorubicin (Dox) sensitivity of colorectal cancer cells by targeting ABCB1 transcription

Cancer Chemotherapy and Pharmacology

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A phase II study of adjuvant S-1/cisplatin chemotherapy followed by S-1-based chemoradiotherapy for D2-resected gastric cancer

Cancer Chemotherapy and Pharmacology

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Phase I/II study of nab-paclitaxel plus gemcitabine for chemotherapy-naive Japanese patients with metastatic pancreatic cancer

Cancer Chemotherapy and Pharmacology

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Risk of recurrence of Barrett’s esophagus after successful endoscopic therapy: a systematic review and meta-analysis

Gastrointestinal Endoscopy

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Loss of visceral adipose tissue precedes subcutaneous adipose tissue and associates with n-6 fatty acids content

Clinical Nutrition

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Tropheryma whipplei infection and Whipple's disease

The Lancet Infectious Diseases

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Objective prediction of pharyngeal swallow dysfunction in dysphagia through artificial neural network modeling

Neurogastroenterology & Motility

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Fecal calprotectin in the prediction of postoperative recurrence of Crohn's disease in children and adolescents

Journal of Pediatric Surgery

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Adrenomedullin therapy in patients with refractory ulcerative colitis

Digestive Diseases and Sciences

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Obese patients with type 2 diabetes on conventional versus intensive insulin therapy: Efficacy of low-calorie dietary intervention

Advances in Therapy

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Frequency and features of duodenal adenomas in patients with mutyh-associated polyposis

Clinical Gastroenterology and Hepatology

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Evidence-based clinical practice guidelines for peptic ulcer disease 2015

Journal of Gastroenterology

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Rare Variants of the Serotonin Transporter Are Associated With Psychiatric Comorbidity in Irritable Bowel Syndrome

Biological Research For Nursing

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A multicenter, randomized, double-blind, placebo-controlled trial of shuangbai san for treating primary liver cancer patients with cancer pain

Journal of Pain and Symptom Management

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Management of branch-duct intraductal papillary mucinous neoplasms: a large single-center study to assess predictors of malignancy and long-term outcomes

Gastrointestinal Endoscopy

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Depression, fatigue, and qol in colorectal cancer patients during and after treatment

Western Journal of Nursing Research

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Perioperative considerations in children with autism spectrum disorder.

Purpose of review: Children with autism often present a challenge to the anesthesiologist. This review summarizes the current experiences and recommendations for the perioperative management of this unique group of patients. Recent findings: Autism is the fastest growing neurodevelopmental disorder in the world. Increased recognition and public awareness of the disease is driven largely by the advances in research. A large body of evidence exists that identifies the role of genetic, environmental, biological, and developmental factors in the origin of autism. The anesthesia literature consists mostly of case reports. Recent publications are reporting management strategies and evaluation of this patient population's perioperative experiences. Summary: Patients with autism spectrum disorder are a heterogeneous group and often need general anesthesia for different procedures and studies. Familiarity with each patient's behavioral specifics and efforts to alleviate stress is of paramount importance for a smooth perioperative course with minimal adverse events. Copyright (C) 2016 YEAR Wolters Kluwer Health, Inc. All rights reserved.

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Surgical treatment of craniosynostosis in infants: open vs closed repair.

Purpose of review: Correction of craniosynostosis may require extensive surgical interventions with related intra and postoperative complications especially hemorrhage. To reduce the intervention's impact and associated complications, less invasive surgical alternatives have evolved. The present review comprehensively summarizes surgical techniques, perioperative anesthesia management, success rates, complications, the results of outcome evaluations, and predictors of intra and postoperative complications. Recent findings: Recent evaluations suggest that less invasive methods represent valuable techniques with comparable cosmetic and volumetric results but reduced overall impact and complications. Furthermore, risk stratification based on predictors might optimize safety and guide decision-making concerning the required level of postoperative clinical care. Summary: Neuroendoscopic techniques, designed to minimize surgical incision, dissection, and blood loss, are becoming efficacious and valuable alternative therapeutic options reducing the need for fluid replacement and invasive hemodynamic monitoring. Since hemorrhage represents the most important complication in open craniosynostosis repair, prevention strategies such as the use of tranexamic acid should be considered. Sufficient correction of entailed coagulopathies is crucial. Copyright (C) 2016 YEAR Wolters Kluwer Health, Inc. All rights reserved.

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Anaesthetic induction with etomidate in cardiac surgery: A randomised controlled trial.

BACKGROUND: Etomidate is perceived as preserving haemodynamic stability during induction of anaesthesia. It is also associated with adrenocortical dysfunction. The risk/benefit relationship is controversial. OBJECTIVES: We tested the hypotheses that single-dose etomidate increases cumulative vasopressor requirement, time to extubation and length of stay in the ICU. DESIGN: Double-blind randomised controlled trial. SETTING: Bern University Hospital, Switzerland, from November 2006 to December 2009. PATIENTS: There were 90 patients undergoing coronary artery bypass grafts (CABG) and 40 patients undergoing mitral valve surgery (MVS). Reasons for noninclusion were known adrenocortical insufficiency, use of etomidate or propofol within 1 week preoperatively, use of glucocorticoids within 6 months preoperatively, severe renal or liver dysfunction, or carotid stenosis. INTERVENTIONS: CABG patients were allocated randomly to receive either etomidate 0.15 mg kg-1 with placebo, propofol 1.5 mg kg-1 with placebo or etomidate 0.15 mg kg-1 with hydrocortisone (n = 30 in each arm). Risk stratification (low vs. high) was achieved by block randomisation. MVS patients received either etomidate 0.15 mg kg-1 or propofol 1.5 mg kg-1 (n = 20 in each arm). MAIN OUTCOME MEASURES: Cumulative vasopressor requirements, incidence of adrenocortical insufficiency, length of time to extubation and length of stay in ICU. RESULTS: Cumulative vasopressor requirements 24 h after induction did not differ between treatments in patients who underwent CABG, whereas more noradrenaline was used in MVS patients following propofol induction (absolute mean difference 5.86 [mu]g kg-1 over 24 h P = 0.047). The incidence of relative adrenocortical insufficiency was higher after etomidate alone than propofol (CABG 83 vs. 37%, P

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