Πέμπτη, 25 Ιουλίου 2019

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,


Morphology of the Middle Ear Ossicles in the Rodent Perimys (Neoepiblemidae) and a Comprehensive Anatomical...
Morphology of the Middle Ear Ossicles in the Rodent Perimys (Neoepiblemidae) and a Comprehensive Anatomical and Morphometric Study of the Phylogenetic Transformations of these Structures in CaviomorphsAbstractThe extinct clade of caviomorph rodents Neoepiblemidae includes forms that lived in South America from the early Miocene to Pliocene. Among them is Perimys. The exceptional preservation of ear ossicles in this rodent is described and analyzed in a study of the phylogenetic transformations of...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:41
Dual PPARα/γ agonist aleglitazar confers stroke protection in a model of mild focal brain ischemia...
Dual PPARα/γ agonist aleglitazar confers stroke protection in a model of mild focal brain ischemia .....in miceAbstractPeroxisome proliferator-activated receptors (PPARs) control the expression of genes involved in glucose homeostasis, lipid metabolism, inflammation, and cell differentiation. Here, we analyzed the effects of aleglitazar, a dual PPARα and PPARγ agonist with balanced affinity for either subtype, on subacute stroke outcome. Healthy young adult mice were subjected to transient 30 min...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:38
Thermo mammogram as a tool to assess response to neoadjuvant chemotherapy in breast carcinoma Subbiah...
Thermo mammogram as a tool to assess response to neoadjuvant chemotherapy in breast carcinomaSubbiah Shanmugam, Gopu Govindasamy, Sujay Susikar, Muniasamy PalaniyandiIndian Journal of Medical and Paediatric Oncology 2019 40(5):25-32Introduction: Response to neoadjuvant chemotherapy (NACT) is predicted by clinical examination alone in locally advanced breast carcinoma. This study uses thermo mammogram (TMG) to assess the response. Aim and Objectives: The aim is to study TMG changes during NACT in...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:37
Head and neck squamous cell carcinoma in young adults: A hospital-based study Jagannath Dev Sharma,...
Head and neck squamous cell carcinoma in young adults: A hospital-based studyJagannath Dev Sharma, Nizara Baishya, Amal Chandra Kataki, Chandi Ram Kalita, Ashok Kumar Das, Tashnin RahmanIndian Journal of Medical and Paediatric Oncology 2019 40(5):18-22Background: Head and neck cancers (HNCs) account for 30% of all cancers in India. In north eastern India, tobacco-related cancers are very common because of the widespread use of tobacco. The paucity of any study from this region in young head and neck...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:36
Coalescence Models Reveal the Rise of the White-Bellied Rat ( Niviventer confucianus ) Following the...
Coalescence Models Reveal the Rise of the White-Bellied Rat ( Niviventer confucianus ) Following the Loss of Asian MegafaunaAbstractRodents are the major remaining mammals in many terrestrial ecosystems after the historical loss of megafauna and large-bodied taxa. Niviventer confucianus is a dominant habitat generalist in natural forests in most of China. It is also recorded as an important vector of diverse zoonotic diseases. Here, three mitochondrial and one nuclear DNA fragments were sequenced...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:36
Introduction to the multi-author review on methylation in cellular physiology Abstract Protein post-translational...
Introduction to the multi-author review on methylation in cellular physiologyAbstractProtein post-translational modifications (PTMs) have long been a topic of intensive investigation. Covalent additions to the 20 genetically encoded amino acids can alter protein interactions and can even change enzymatic function. In eukarya, PTMs can amplify both the complexity and functional paradigms of the cellular environment. Therefore, PTMs have been of substantial research interest, both for understanding...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:35
Avoiding Brooms, Forks, and Butterflies in the Linear Lattices Abstract Let n be a positive integer, q a...
Avoiding Brooms, Forks, and Butterflies in the Linear LatticesAbstractLet n be a positive integer, q a power of a prime, and \(\mathcal {L}_{n}({q})\) the poset of subspaces of an n-dimensional vector space over a field with q elements. This poset is a normalized matching poset and the set of subspaces of dimension ⌊n/2⌋ or those of dimension ⌈n/2⌉ are the only maximum-sized antichains in this poset. Strengthening this well-known and celebrated result, we show that, except in the case of \(\mathcal...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:35
Elevated expression of CST1 promotes breast cancer progression and predicts a poor prognosis In Figure...
Elevated expression of CST1 promotes breast cancer progression and predicts a poor prognosisIn Figure 7f the panel for c-myc of MDA-MB-468 was erroneously duplicated. The corrected version of the figure is shown in this paper. This correction does not influence the conclusion of the study and we sincerely apologize for this oversight.Correction to: STIM1 deficiency is linked to Alzheimer's disease and triggers cell death in SH-SY5Y cells by upregulation of L-type voltage-operated Ca 2+ entryThe original...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:32
Bone marrow infiltration by nonhematopoetic small round cell tumors: A clinicopathological study from...
Bone marrow infiltration by nonhematopoetic small round cell tumors: A clinicopathological study from a tertiary care centre in South IndiaTriveni Bhopal, Abid Hussain, Sai Mallikarjun, Sree Lakshmi, Sudha SinhaIndian Journal of Medical and Paediatric Oncology 2019 40(5):1-5Objectives: The objective of this study to comprehensively analyze bone marrow (BM) infiltration by nonhematological round cell tumors. Materials and Methods: A total of 206 diagnosed cases of small round blue cell tumors (excluding...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:31
Inferring the history of surname Ye based on Y chromosome high-resolution genotyping and sequencing...
Inferring the history of surname Ye based on Y chromosome high-resolution genotyping and sequencing dataZhen Zeng, Jiaoyang Tian, Chuangui Jiang, Weijian Ye, Kaijun Liu et al. Journal of Human Genetics 2019 64 :703 - 709; May 15, 2019; 10.1038/s10038-019-0616-2Abstract | Full TextClinical and genetic analysis of patients with primary ciliary dyskinesia caused by novel DNAAF3 mutationsZhuoyao Guo, Weicheng Chen, Jianfeng Huang, Libo Wang & Liling Qian Journal of Human Genetics 2019 64 :711 - 719;...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:29
National Cancer Institute theNCI25 JulRT @NCIDrDougLowy: At @theNCI we are training the next generation...
National Cancer Institute theNCI25 JulRT @NCIDrDougLowy: At @theNCI we are training the next generation of cancer researchers—both in our intramural program and by funding train…Details  |  RetweetNational Cancer Institute theNCI25 JulA program called #NCICONNECT from @NIHBrainTumor aims to study 12 rare brain and spine tumors to improve approaches… https://t.co/xQeSRnX6jTDetails  |  RetweetNational Cancer Institute theNCI24 JulNeuroblastoma is a cancer of immature nerve cells that most often occurs...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:27
First-in-human gene therapy launches for pediatric patient with rare neurogenerative disease  In May,...
First-in-human gene therapy launches for pediatric patient with rare neurogenerative disease In May, a ten-year-old girl named JoJo received gene therapy for an extremely rare neurogenerative disease called GM1 gangliosidosis. GM1 progressively destroys nerve cells (neurons) in the brain and spinal cord, leading to muscle and movement weakness, difficulty swallowing and a shortened life expectancy. 
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:16
Fermentative Escherichia coli makes a substantial contribution to H2 production in coculture with phototrophicRhodopseudomonas...
Fermentative Escherichia coli makes a substantial contribution to H2 production in coculture with phototrophicRhodopseudomonas palustris    Amee A Sangani; Alexandra L McCully; Breah LaSarre ; James B McKinlay
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:15
Case fatality ratio estimates for the 2013 – 2016 West African Ebola epidemic: application of Boosted...
Case fatality ratio estimates for the 2013 – 2016 West African Ebola epidemic: application of Boosted Regression Trees for imputation    Alpha Forna, MSc ; Pierre Nouvellet, PhD; Ilaria Dorigatti, PhD; Christl A Donnelly, ScD  Plazomicin: A New Aminoglycoside  Louis D Saravolatz, MD, MACP, FIDSA; Gary E Stein, PharmD
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:15
Notes on Church-State Affairs    David W Hendon; Scott Prather 
Notes on Church-State Affairs    David W Hendon; Scott Prather 
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:15
Space as Testimony: Collecting Oral Histories Among Nigerian Seamen    Lynn Schler
Space as Testimony: Collecting Oral Histories Among Nigerian Seamen    Lynn Schler
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:14
Unity and Plurality. Logic, Philosophy, and Linguistics    Riccardo Baratella  The Possibility of Unity  H...
Unity and Plurality. Logic, Philosophy, and Linguistics    Riccardo Baratella  The Possibility of Unity  H W Noonan  Manipulated Agents: A Window to Moral Responsibility  Taylor W Cyr  Working from Within: The Nature and Development of Quine's Naturalism  Ali Hossein Khani  Deflating Deflationary Truthmaking  Jamin Asay; Sam Baron  Determined by Reasons: A Competence Account of Acting for a Normative Reason  J J Cunningham
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:14
Fanconi anemia study using eltrombopag Volunteers at least 4 years of age with Fanconi anemia are...
Fanconi anemia study using eltrombopagVolunteers at least 4 years of age with Fanconi anemia are needed for a research study.Fanconi anemia is a rare genetic disorder that mostly affects children and often leads to bone marrow failure. Researchers at the National Institutes of Health (NIH) are investigating a new drug to improve blood counts in individuals diagnosed with Fanconi anemia. Eltrombopag is an oral drug that mimics a special protein that causes the body to make more platelets. Currently...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:13
  Comparison of Original and 2018 Lake Louise Criteria for Diagnosis of Acute Myocarditis: Results...
 Comparison of Original and 2018 Lake Louise Criteria for Diagnosis of Acute Myocarditis: Results of a Validation Cohort The 2018 Lake Louise criteria provide a high diagnostic accuracy for the diagnosis of acute myocarditis and significantly increase the sensitivity compared with the original score.   Julian A. Luetkens, Anton Faron... Daniel Thomas
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:13
Realizing Shared Decision-making in Practice   Mary Catherine Beach, MD, MPH; Jeremy Sugarman, MD,...
Realizing Shared Decision-making in Practice  Mary Catherine Beach, MD, MPH; Jeremy Sugarman, MD, MPH, MAHarms From Uninformative Clinical TrialsDeborah A. Zarin, MD; Steven N. Goodman, MD, MHS, PhD; Jonathan Kimmelman, PhDShared Decision Making and the Importance of Time
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:12
JAMA Otolaryngology–Head & Neck Surgery
ORIGINAL INVESTIGATIONAssociation Between Annual Surgeon Total Thyroidectomy Volume and Transient and Permanent ComplicationsCharles Meltzer, MD; Michaela Hull, MS; Alvina Sundang, MBA; et alComparison of 3- vs 2-Dimensional Endoscopy Using Eye Tracking and Assessment of Cognitive Load Among Surgeons Performing Endoscopic Ear SurgeryLukas Anschuetz, MD; Laura Niederhauser, MSc; Wilhelm Wimmer, PhD; et alREVIEWAssociation of Preoperative, Subjective Pediatric Tonsil Size With Tonsillectomy Outcomes: A...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:11
Serious Bacterial Infections in Neonates Presenting Afebrile With History of Fever   Sriram Ramgopal,...
Serious Bacterial Infections in Neonates Presenting Afebrile With History of Fever  Sriram Ramgopal, Lorne W. Walker, Melissa M. Tavarez, Andrew J. Nowalk and Melissa A. VitaleMonthly FeatureThe Fight Over the Juvenile Giant: Contesting Growth in the 1930sSamuel V. SchotlandQuality ReportUsing Quality Improvement to Implement a Standardized Approach to Neonatal Herpes Simplex VirusLaura H. Brower, Paria M. Wilson, Eileen Murtagh Kurowski, David Haslam, Joshua Courter, Neera Goyal, Michelle Durling,...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:09
Impact of an Outpatient Cardiology-managed Urgent Access and Observation Unit on Hospital Admissions...
Impact of an Outpatient Cardiology-managed Urgent Access and Observation Unit on Hospital AdmissionsIntroduction: Alternatives to the emergency department (ED) for expedient and high-value team-based cardiology care for patients with chest pain, volume overload, palpitations, and other urgent, but not life-threatening cardiac conditions are lacking. Here, we report on the development of the Cardiac Direct Access Unit (CDAc), an ambulatory cardiology unit with exam rooms, observation bays, and an...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:04
Negative priming is diminished under high blood pressure in healthy subjects Abstract The ability to...
Negative priming is diminished under high blood pressure in healthy subjectsAbstractThe ability to ignore distracting objects is a core mechanism in selective attention and has been analyzed particularly with respect to its clinical implications (e.g., depression, schizophrenia, or unhealthy life-style). Here, we investigated the correlation between an established experimental task to measure distractor-processing and participants' blood pressure. We used the negative priming (NP) task in which participants...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:03
Strategic cooperation for transnational adaptation: lessons from the economics of climate change mitigation...
Strategic cooperation for transnational adaptation: lessons from the economics of climate change mitigationAbstractThe literature on climate adaptation has so far conceptualized it as a domestic issue, to be governed somewhere between the local and the national scale. By contrast, scholars have shown little interest in exploring the case of cross-boundary adaptation spillovers, where adaptation by one country affects other countries. Two decades of the economic literature on climate mitigation may...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:03
Design of a synthetic miniR1 plasmid and its production by engineered Escherichia coli Abstract A synthetic...
Design of a synthetic miniR1 plasmid and its production by engineered Escherichia coliAbstractA synthetic plasmid consisting of the minimal elements for replication control of the R1 replicon and kanamycin resistance marker, which was named pminiR1, was developed. pminiR1 production was tested at 30 °C under aerobic and microaerobic conditions in Escherichia coli W3110 recA− (W1). The plasmid DNA yields from biomass (YpDNA/X) were only 0.06 ± 0.02 and 0.22 ± 0.11 mg/g under aerobic and microaerobic...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:02
White Matter Lesion Penumbra Shows Abnormalities on Structural and Physiologic MRIs in the Coronary...
White Matter Lesion Penumbra Shows Abnormalities on Structural and Physiologic MRIs in the Coronary Artery Risk Development in Young Adults CohortI.M. Nasrallah, M.-K. Hsieh, G. Erus, H. Battapady, S. Dolui, J.A. Detre, L.J. Launer, D.R. Jacobs, C. Davatzikos and R.N. BryanAJNR Am J Neuroradiol first published on 25 July 2019 doi:10.3174/ajnr.A6119 OPEN ACCESS ARTICLEhttp://www.ajnr.org/content/early/2019/07/25/ajnr.A6119.abstractSignal Hyperintensity on Unenhanced T1-Weighted Brain and Cervical...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:02
Shiraz Organ Transplant Center: The Largest Liver Transplant Center in the World No abstract available...
Shiraz Organ Transplant Center: The Largest Liver Transplant Center in the WorldNo abstract availableResearch HighlightsNo abstract availableB Cell Recruitment Follows Kidney Injury and Maladaptive RepairNo abstract availablePeople in TransplantationNo abstract availableVisual Abstracts (#VisualAbstract): A New Journal Initiative to Disseminate ResearchNo abstract availableOrgans From Executed People Are Not a Source of Scientific DiscoveryNo abstract availablePatient Selection and Ethical Considerations—Justifying...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:01
Does Women's Health Matter? No abstract available Restriction in Pelvis and Trunk Motion in Postpartum...
Does Women's Health Matter?No abstract availableRestriction in Pelvis and Trunk Motion in Postpartum Runners Compared With Pre-pregnancyBackground: Biomechanical changes in gait during pregnancy have been well studied in walking but not in running. Objective: To specifically examine adaptations in running biomechanics pre- to post-pregnancy, especially in the pelvis and trunk. Study Design: Pilot study. Methods: Five regular runners who were pregnant for the first time participated in this study....
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:00
Vegetarian Diet Patterns and Chronic Disease Risk: What We Know and What We Don't Vegetarianism continues...
Vegetarian Diet Patterns and Chronic Disease Risk: What We Know and What We Don'tVegetarianism continues to increase globally due, in part, to perceived health benefits. Results from observational studies indicate that vegetarian dietary patterns are associated with favorable cardiometabolic risk factor profiles and lower risks of chronic diseases including obesity, diabetes mellitus type 2, cardiovascular disease, and cancer. Aside from avoidance of meat and the compensatory dietary alterations,...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
08:59
Trauma
Tranexamic Acid Use in Open Reduction and Internal Fixation of Fractures of the Pelvis, Acetabulum, and Proximal Femur: A Randomized Controlled TrialObjective: To assess the safety and efficacy of tranexamic acid (TXA) use in fractures of the pelvic ring, acetabulum, and proximal femur. Design: Prospective, randomized controlled trial. Setting: Single Level 1 trauma center. Patients: Forty-seven patients were randomized to the study group, and 46 patients comprised the control group. Intervention:...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
08:57
Tranexamic Acid Use in Open Reduction and Internal Fixation of Fractures of the Pelvis, Acetabulum,...
Tranexamic Acid Use in Open Reduction and Internal Fixation of Fractures of the Pelvis, Acetabulum, and Proximal Femur: A Randomized Controlled TrialObjective: To assess the safety and efficacy of tranexamic acid (TXA) use in fractures of the pelvic ring, acetabulum, and proximal femur. Design: Prospective, randomized controlled trial. Setting: Single Level 1 trauma center. Patients: Forty-seven patients were randomized to the study group, and 46 patients comprised the control group. Intervention:...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
08:57
Toward Achieving Risk-Appropriate Maternity Care: Maternal Morbidity Prediction No abstract available...
Toward Achieving Risk-Appropriate Maternity Care: Maternal Morbidity PredictionNo abstract availablePredictive Model of Factors Associated With Maternal Intensive Care Unit AdmissionOBJECTIVE: Severe maternal morbidity has increased in the United States over the past two decades by approximately 200%, to 144 cases per 10,000 delivery hospitalizations. There are limited data available to assist in identifying at-risk women before parturition. We sought to evaluate risk factors associated with maternal...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
08:56
Breast Reconstruction
Fat Grafting and the Palpable Breast Mass in Implant-Based Breast Reconstruction: Incidence and ImplicationsBackground: Fat grafting is a powerful and increasingly used technique in breast reconstruction. However, fat necrosis can lead to palpable postoperative changes that can induce anxiety and lead to unplanned diagnostic studies. The authors' aim in this study was to evaluate the incidence, type, and timing of these unanticipated studies; the specialty of the ordering provider; and the factors...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
08:54
Plastic and Reconstructive Surgery
Pediatric/Craniofacial Article: Focus of Live Facebook #PRSJournalClub Q&ASurvival Following Self-inflicted Gunshots to the FaceSpecial Topic Article with an Expert DiscussionThe Use of Emotional Artificial Intelligence in Plastic SurgeryCosmetic Article Featured in the PressAppreciation of Postpartum Changes of the Rectus Muscles in Primary and Re-Do AbdominoplastyHead and Neck Article Featured in a Plastic Surgery Hot Topic VideoFacial Transplantation for an Irreparable Central and Lower Face...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
08:53
Fat Grafting and the Palpable Breast Mass in Implant-Based Breast Reconstruction: Incidence and Implications...
Fat Grafting and the Palpable Breast Mass in Implant-Based Breast Reconstruction: Incidence and ImplicationsBackground: Fat grafting is a powerful and increasingly used technique in breast reconstruction. However, fat necrosis can lead to palpable postoperative changes that can induce anxiety and lead to unplanned diagnostic studies. The authors' aim in this study was to evaluate the incidence, type, and timing of these unanticipated studies; the specialty of the ordering provider; and the factors...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
08:53
Prolyl Tripeptidylpeptidase   Yoshitaka Nakajima, ... Tadashi Yoshimoto, in Handbook of Proteolytic...
Prolyl Tripeptidylpeptidase  Yoshitaka Nakajima, ... Tadashi Yoshimoto, in Handbook of Proteolytic Enzymes (Third Edition), 2013Biological AspectsPorphyromonas gingivalis is a Gram-negative anaerobic bacteriumand is considered to be a major pathogen associated with periodontitis. Since this bacterium is known to be a very poor carbohydrate utilizer and cannot take up free amino acids, it only utilizes short oligopeptides as carbon and energy sources. P. gingivalis produces gingipains R and K, collagenase,...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
08:50
Rheumatoid Arthritis and Infections    Hussein Mahajna, ... Howard Amital, in Infection and Autoimmunity...
Rheumatoid Arthritis and Infections   Hussein Mahajna, ... Howard Amital, in Infection and Autoimmunity (Second Edition), 2015Gingival infection caused by is another that is associated with RA. It is postulated that this microbe causes a citrullination process in human proteins that leads to a cascade causing autoimmunity.26Periodontitis, in which P. gingivalis is a major pathogenic bacterium, has been linked to RA in epidemiological studies, and they share similar genomic and environmental associations....
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
08:49
Karilysin    Jan Potempa, ... Abdulkarim Y. Karim, in Handbook of Proteolytic Enzymes (Third Edition),...
Karilysin   Jan Potempa, ... Abdulkarim Y. Karim, in Handbook of Proteolytic Enzymes (Third Edition), 2013Name and HistoryTannerella forsythia (formerly Bacteroides forsythus), together withand Treponema denticola, are considered to be the major periodontal pathogens [1]. A common feature of these organisms is the production of high levels of proteolytic activity. This activity is considered an important virulence factor contributing to pathological chronic inflammation, which drives tissue damage...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
08:49

Metallocarboxypeptidase G (Porphyromonas gingivalis)   Yu-Yen Chen, ... Eric C. Reynolds, in Handbook...
Metallocarboxypeptidase G (Porphyromonas gingivalis)  Yu-Yen Chen, ... Eric C. Reynolds, in Handbook of Proteolytic Enzymes (Third Edition), 2013Name and HistoryThe first isolated carboxypeptidase from Porphyromonas gingivaliswas reported in 2002 by two independent research groups. Masuda et al. [1] reported the isolation of 'Arg carboxypeptidase' (RCP) from strain W381, which was resolved by SDS-PAGE into three major bands of 43, 33 and 32 kDa with identical N-terminal amino acid sequences (YEWNAYPTYEAYISMMEEFQTKYPSLXTXS)....
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
08:49
Acute orofacial pain   Yair Sharav, Rafael Benoliel, in Orofacial Pain and Headache, 2008Pathophysiology...
Acute orofacial pain  Yair Sharav, Rafael Benoliel, in Orofacial Pain and Headache, 2008PathophysiologyHigh prevalences of putative periodontal pathogens including Fusobacterium nucleatum, Peptostreptococcus micros, Porphyromonas gingivalis, Prevotella intermedia and Bacteroides forsythus were found in periodontal abscesses (Herrera et al 2000a).Significant differences in the levels of prostaglandin E2 (PGE2) and LTB4 were found between patients with and without periodontitis. The PGE2 and LTB4 levels...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
08:48
Phage therapy against Enterococcus faecalis in dental root canals
J Oral Microbiol. 2016; 8: 10.3402/jom.v8.32157.Published online 2016 Sep 16. doi: 10.3402/jom.v8.32157PMCID: PMC5027333PMID: 27640530Leron Khalifa,1 Mor Shlezinger,2 Shaul Beyth,3 Yael Houri-Haddad,2 Shunit Coppenhagen-Glazer,1 Nurit Beyth,2,†and Ronen Hazan1,*†Author information Article notes Copyright and License information Disclaimer1Institute of Dental Science, The Hebrew University Hadassah School of Dental Medicine, Jerusalem, Israel2Department of Prosthodontics, The Hebrew University Hadassah...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
08:47
Bilateral intermittent nasal obstruction in adolescent rats leads to the growth defects of mandibular...
Bilateral intermittent nasal obstruction in adolescent rats leads to the growth defects of mandibular condyle Publication date: October 2019Source: Archives of Oral Biology, Volume 106Author(s): Xiaoling Wang, Huijun Sun, Yanfei Zhu, Yanmei Tang, Xiaochen Xue, Ping Nie, Min Zhu, Bing WangAbstractObjectiveThis study aimed to evaluate the effects of nasal obstruction on mandibular growth, especially condyle, in adolescent rats and explore the possible mechanism with a focus on mesenchymal stem cells...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
08:45
Porphyromonas gingivalis: An Overview of Periodontopathic Pathogen below the Gum Line,  Kah Yan How,1,* Keang...
Porphyromonas gingivalis: An Overview of Periodontopathic Pathogen below the Gum Line, Kah Yan How,1,* Keang Peng Song,2 and Kok Gan Chan1Author information Article notes Copyright and License information Disclaimer1Division of Genetics and Molecular Biology, Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia2School of Science, Monash University Sunway Campus, Subang Jaya, MalaysiaEdited by: Laurel L. Lenz, University of Colorado School of Medicine,...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
08:44
Porphyromonas gingivalis lipopolysaccharide promotes T- helper 17 cell differentiation from human CD4+ naïve...
Porphyromonas gingivalis lipopolysaccharide promotes T- helper 17 cell differentiation from human CD4+ naïve T cells via toll-like receptor-2 in vitroPublication date: November 2019Source: Archives of Oral Biology, Volume 107Author(s): Liping Zhang, Li Gao, Chenrong Xu, Xiting Li, Panpan Wang, Chi Zhang, Chuanjiang ZhaoAbstractObjectivesThe persistence of T-helper 17 (Th17) cells has been shown to support chronic inflammation and mediate tissue destruction in periodontitis. However, little is known...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
08:40
Carabid community stability is enhanced by carabid diversity but reduced by aridity in Chinese steppes...
Carabid community stability is enhanced by carabid diversity but reduced by aridity in Chinese steppesPublication date: August 2019Source: Acta Oecologica, Volume 99Author(s): Noelline Tsafack, Letizia Di Biase, Yingzhong Xie, Xinpu Wang, Simone FattoriniAbstractCarabids (Coleoptera, Carabidae) are an important arthropod component of grassland ecosystems, where they are involved in many important ecosystem services. Grasslands are the most widespread ecosystems in China, where they are under increasing...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
08:38
Brain tissue segmentation using improved kernelized rough-fuzzy C-means with spatio-contextual information...
Brain tissue segmentation using improved kernelized rough-fuzzy C-means with spatio-contextual information from MRIPublication date: October 2019Source: Magnetic Resonance Imaging, Volume 62Author(s): Anindya Halder, Nur Alom TalukdarAbstractSegmentation of brain tissues from MRI often becomes crucial to properly investigate any region of the brain in order to detect abnormalities. However, the accurate segmentation of the brain tissues is a challenging task as the different tissue regions are usually...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
08:38
Thoughts and Words
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
08:37
Health of asylum-seeking immigrants: Providing medical care from a volunteer's perspective No abstract...
Health of asylum-seeking immigrants: Providing medical care from a volunteer's perspectiveNo abstract availableUsing pharmacogenetics in primary carePharmacogenetics offers a way to personalize medication prescribing for patients. Through the use of genetic tests that identify variations in enzymes important to drug metabolism, PAs can have patients' genetic information before prescribing a medication. This may reduce the risks of adverse reactions and lost treatment time when patients are given...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
08:34
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
A comparison of the academic performance and intelligence scores of asthmatic and nonasthmatic primary...A comparison of the academic performance and intelligence scores of asthmatic and nonasthmatic primary school pupils in Enugu State, NigeriaObinna Chukwuebuka NduagubamNigerian Medical Journal 2019 60(1):1-8Background: Children with asthma (subjects), just as their non asthmatic colleagues, are expected to perform optimally academically and with a good intelligent score. A number of activities...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
Thu Jul 25, 2019 12:51
Urogynecology
Commentary to: Prospective comparative study on the effects of lidocaine on urodynamic and sensory parameters in bladder-pain syndromeCommentary on: "Does spinal anesthesia lead to postoperative urinary retention in same day urogynecology surgery: a retrospective review"Treatment of subacute rectosigmoid obstruction secondary to uterosacral ligament suspensionThe transition from resident to consultantA live porcine model for robotic sacrocolpopexy trainingAbstractIntroduction and hypothesisRobotic...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
Thu Jul 25, 2019 09:18
Clinical Oncology,Pediatric Hematology/Oncology
Maintenance Therapy in Metastatic Solid Tumors: Innovative Strategy or Simple Second-line Treatment?Managing metastatic diseases involves defining the best strategy that is supposed to take into account both efficacy and quality of life. To this end, clinicians use stop and go or maintenance strategies. As a matter of fact, 2 maintenance strategies can be distinguished: continuation maintenance using a drug already present in induction treatment and switch maintenance with a newly introduced drug....
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
Thu Jul 25, 2019 09:12
Clinical Rheumatology
Folate Supplementation for Methotrexate Therapy in Patients With Rheumatoid Arthritis: A Systematic ReviewObjective To review the evidence for benefits and harms of folate (folic acid or folinic acid) supplementation on methotrexate (MTX) treatment for rheumatoid arthritis (RA), to assess whether or not folate supplementation would reduce MTX toxicity or reduce MTX benefits, and to decide whether a higher MTX dosage is essential. Methods We performed a sensitive search strategy and searched systematically...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
Thu Jul 25, 2019 09:04
Clinical Obstetrics and Gynecology
Contributors: Burnout and Resilience in Obstetrics and GynecologyNo abstract availableForeword: Burnout and Resilience in Obstetrics and GynecologyNo abstract availableBurnout in Obstetricians and GynecologistsProfessional burnout threatens all high-functioning professionals and affects not only the individual, but, by extension, the patients they serve. The characteristics that make someone competitive for medical school, residency, or successful in academics or practice, make us particularly vulnerable...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
Thu Jul 25, 2019 09:03
Implant Dentistry
Device Legislation...... Now Tread CautiouslyNo abstract availableThe Sinus Bone Graft— Third Edition 2019No abstract availableRidge Architecture Preservation Following Minimally Traumatic Exodontia Techniques and Guided Tissue RegenerationObjective: To compare hard-tissue healing after 3 exodontia approaches. Materials and Methods: Premolars of dogs were extracted: (1) flapless, (2) flap, and (3) flap + socket coverage with polytetrafluoroethylene (dPTFE) nonresorbable membrane (flap + dPTFE). Animals...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
Thu Jul 25, 2019 09:00
Dermatologic Surgery
Use of Autologous, Noncultured Melanocyte–Keratinocyte Transplantation in Patients With Stable Genital LeucodermaNo abstract availableA Closure Option for Sinuous Hairline Preservation on the Upper ForeheadNo abstract availableSharp Debulking and Nonbeveled Layers in Mohs Micrographic Surgery, A Video Walkthrough: How We Do ItNo abstract availableVulvar Lichen Sclerosus: Consider Treatment With Heterologous Type I CollagenNo abstract availableEfficacy, Patient-Reported Outcomes, and Safety in Male...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
Thu Jul 25, 2019 08:55