A comparison of the academic performance and intelligence scores of asthmatic and nonasthmatic primary school pupils in Enugu State, NigeriaObinna Chukwuebuka NduagubamNigerian Medical Journal 2019 60(1):1-8Background: Children with asthma (subjects), just as their non asthmatic colleagues, are expected to perform optimally academically and with a good intelligent score. A number of activities in children with asthma may be affected by asthmatic attacks including their education/academic performance....
Comparative pathogenicity of opportunistic black yeasts in Aureobasidium Meizhu Wang, Patrizia Danesi, Timothy Y. James, Abdullah M. S. Al‐Hatmi, Mohammad Javad Najafzadeh, Somayeh Dolatabadi, Chunyan Ming, Guey‐Yuh Liou, Yingqian Kang, Sybren de HoogVersion of Record online: 19 July 2019Defining breakthrough invasive fungal infection–Position paper of the mycoses study group education and research consortium and the European Confederation of Medical MycologyOliver A. Cornely, Martin Hoenigl, Cornelia...
Gliotoxin and bis(methylthio)gliotoxin are not reliable as biomarkers of invasive aspergillosis Toine Mercier, Agustin Reséndiz Sharpe, Dieter Waumans, Koen Desmet, Katrien Lagrou, Johan MaertensFirst Published: 17 July 2019
Cattle TB detection gets better testin ChemistrySensor that can sniff out explosives in battlefieldsin ChemistryDNA-based nanodevices for detecting nerve disordersin Cell & molecular biologyNew lineage of vine snake discovered in Ecology & evolutionBacteria use proteins to make sense of their environmentsin Cell & molecular biology Latest news & features Skin lesions are reservoirs for Kala-azar infectionIndia launches second moon missionSubmerged river systems hint at India-Sri...
Biosimilars: A Value Proposition AbstractBiosimilars are biological agents that effectively replicate original reference products. The main driver of their development is the promise of bringing competition into the marketplace, and consequently contributing to the sustainability of healthcare systems. By reducing financial barriers to biological therapies, biosimilars play a part in budgetary redistribution and, hence, in increasing patients' access to treatment. They also foster innovation and...
Action of chlorzoxazone on Ca2+movement and viability in human oral cancer cells,Ti Lu, Wei-Zhe Liang, Lyh-Jyh Hao, Chun-Chi Kuo, Pochuen Shieh, Chiang-Ting Chou, Chung-Ren JanChinese Journal of Physiology 2019 62(3):123-130Chlorzoxazone is a skeletal muscle relaxant. However, the effect of chlorzoxazone on intracellular Ca2+ concentrations ([Ca2+]i) in oral cancer cells is unclear. This study examined whether chlorzoxazone altered Ca2+ signaling and cell viability in OC2 human oral cancer cells....
Histone deacetylases in stroke,Mei-Han Kao, Teng-Nan LinChinese Journal of Physiology 2019 62(3):95-107Stroke is the second leading cause of death and the leading cause of adult disability worldwide. Despite an impressive amount of neuroprotective agents that has been identified in experimental stroke, none of them proved efficient in clinical trials. There is a general consensus that an effective treatment requires the ability to interact with not one, but multiple pathophysiological cascades at...
Sinonasal nonsalivary-type adenocarcinoma: A 9-year experience from a tertiary cancer center in South IndiaKR Anila, K Ramadas, Elizabeth Mathew Iype, TR Preethi, Anitha Mathews, Thara Somanathan, K JayasreeClinical Cancer Investigation Journal 2019 8(3):119-122Background: Sinonasal tract malignancies are uncommon, representing not more than 5% of all head and neck neoplasm. Primary non-salivary type adenocarcinomas of the sinonasal tract are rare and may originate from respiratory surface epithelium...
Correlation between ki-67 labeling index and mitotic index in oral squamous cell carcinomaArchana Buch, Niladri Haldar, Supriya Kheur, Shirish Chandanwale, Harsh KumarClinical Cancer Investigation Journal 2019 8(3):90-95Background: Oral squamous cell carcinoma (OSCC) is the most prevalent type of oral cancer. Counting of mitotic figures as well as the detection of Ki-67 expression by immunohistochemistry have been used to detect cell proliferation in malignant tumors. We correlated Ki-67 expression...
11q23 translocation in children with acute lymphocytic leukemia following primary response to chemotherapy: prognostic significance and diagnostic accuracyArash Alghasi, Kaveh Jaseb, Mohammad Pedram, Bijan Keikhaei, Hadi Rezaeeyan, Hamid Galehdari, Ali Mohammad Malekaskar, Fakher Rahim, Marziyeh Abbasi NasabClinical Cancer Investigation Journal 2019 8(3):79-83Background: Cytogenetic abnormalities in leukemia cells have strong prognostic values for different clinical subgroups, clinical features,...
In silico analysis of RNA-seq requires a more complete description of methodology Joël Simoneau & Michelle S. Scott pp451 - 452 | doi:10.1038/s41580-019-0137-z Simoneau and Scott ask that researchers provide complete descriptions of their choices and parameters of RNA-seq data analysis. Full Text | PDF RESEARCH HIGHLIGHTSER stress boosts respiration Paulina Strzyz p453 | doi:10.1038/s41580-019-0139-x Glucose deprivation induces ER stress, which enhances mitochondrial respiration by promoting...
HIV estimates through 2018: data for decision making,Background: Global targets call for a reduction in new HIV infections and AIDS deaths by 2030. UNAIDS supports countries to measure progress towards these targets. In 2019, this effort resulted in revised national, regional and global estimates reflecting the best available data. Methods: Spectrum software was used to develop estimates for 170 countries. Country teams from 151 countries developed HIV estimates directly and estimates for an additional...
Changes in Fatigue Are the Same for Trained Men and Women after Resistance Exercise,Purpose To measure changes in fatigue and knee-extensor torque in the 48H after trained men and women completed a full-body resistance exercise session. Methods Eight trained women (mean ± SD; age, 25.6 ± 5.9 years; height, 1.68 ± 0.06 m; mass, 71.0 ± 8.6 kg) and eight trained men (age, 25.5 ± 6.2 years; height, 1.79 ± 0.05 m; mass, 86.4 ± 9.8 kg) performed a full-body resistance exercise session based on real-world...
Kasr AL-Ainy's psoriasis unit protocol for the treatment of psoriasis, part II: biological therapiesHoda Rasheed, Hesham A.Z AEl-Moaty, Mohamed H.M El-Komy, Heba Mashaly, Khadiga S Sayed, Vanessa Hafez, Marwa S El-Mesidy, Eman R Said, Marwa A Amer, Aya M AlOrbani, Dina G Saadi, Mona El-Kalioby, Reem O Eid, Yousra AzzaziJournal of the Egyptian Women�s Dermatologic Society 2019 16(2):73-80Psoriasis is a chronic multisystem inflammatory disease affecting primarily the skin and joints but also involves...
Moving Towards Wellness in Long-term Care: Considerations for Dementia-Associated Aggression,AbstractDementia is a debilitating and progressive neurodegenerative condition expected to affect over 13 million Americans by 2050 (Mitchell et al. in N Engl J Med 361:1529–1538, 2009) and 132 million individuals worldwide (Prince et al. in Alzheimer's Res Ther 8(1):23, 2016). Characterized by cognitive and physical loss and change, and loss of one's sense of self, this illness significantly impairs the...
NEUROLOGICAL HEALTH The Role of Seizures in Alzheimer's Disease Is Gaining Overdue Attention,PUBLIC HEALTH The Superbug Candida auris is Giving Rise to Warnings--and Big QuestionsPopulation Health: How We Can Cure What's Ailing Health CareTHE BODY How to Prevent Food AllergiesWhat Does a Medical Nihilist Do When He Gets Sick?PUBLIC HEALTH VW Emissions Cheating Scandal Increased Children's Pollution ExposureTHE BODY The Human Body Is a Mosaic of Different GenomesTaking the Bias out of Pain DiagnosisPUBLIC...
Front MatterPages i-viPDFIntroduction: Towards Zoosemiotics 2.0Gianfranco MarronePages 1-18Animal as Food, Food for AnimalsFront MatterPages 19-19PDFWhen to Eat Meat? Toward a Diet of CaringNicola PerulloPages 21-32Anti-speciesist RhetoricMatteo MeschiariPages 33-41Aesthetics of Nutrition, Ethics of Animality: The Packaging of Vegan and Vegetarian Products in the Italian Organised Distribution MarketIlaria Ventura BordencaPages 43-54Forms of Animality: The DogDario ManganoPages 55-72Pet Food Communication:...
IntroductionFelice CimattiPages 1-4LifeFelice CimattiPages 5-13Scientist Because Philosopher, Philosopher Because ScientistFelice CimattiPages 15-22The Line and the CircleFelice CimattiPages 23-34The Biological Model: For an Anti-Cartesian SemioticsFelice CimattiPages 35-48PDFFrom Complementarity to SemiosisFelice CimattiPages 49-68The Origin of LanguageFelice CimattiPages 69-80Attention and ConsciousnessFelice CimattiPages 81-88Breaking the CircleFelice CimattiPages 89-97Language and EthicsFelice...
Biosemiotics of Mimicry: Introductory Notes Timo Maran Pages 1-10 First Excursion: The History of...
Biosemiotics of Mimicry: Introductory NotesTimo MaranPages 1-10First Excursion: The History of the Mimicry ConceptTimo MaranPages 11-13The Structure of MimicryTimo MaranPages 15-34PDFSemiotics of MimicryTimo MaranPages 35-53Iconicity and MimicryTimo MaranPages 55-63Second Excursion: Importance of the ObjectTimo MaranPages 65-67Different Perspectives in Mimicry SystemTimo MaranPages 69-82Modelling MimicryTimo MaranPages 83-99Mimicry and Semiotic EvolutionTimo MaranPages 101-117Third Excursion: An...
Key Book Series: Biosemiotics Biosemiotics Series Editors: Kalevi Kull, Alexei Sharov, Jesper HoffmeyerThe Springer book series Biosemiotics draws together contributions from leading scholars. It is an unparalleled series that will appeal to all those interested in the origins and evolution of life, including molecular and evolutionary biologists, ecologists, anthropologists, psychologists, philosophers and historians of science, linguists, semioticians and researchers in artificial life, information...
Kidney palliative care can help meet gaps in care A care program combining palliative care with nephrology care in an ambulatory setting has the potential to meet gaps in care and achieving patient satisfaction, according to a study in Journal of Palliative Medicine. Jennifer S. Scherer, MD, at New York University School of Medicine, was the lead author of a study involving 55 patients most with stage IV or V chronic kidney disease. Eighty-seven percent of initial visits included an advance care...
WHO withdraws opioid guidance as groups urge revisions The World Health Organization (WHO) has withdrawn two pain management guidelines, citing new scientific evidence since the guidelines were released in 2011 and 2012. In a statement WHO acknowledged the need for opioids but also that the need must be balanced with concerns about harm and misuse of the drugs. The organization withdrew the guidelines after two members of the U.S. Congress released a report accusing the WHO guidelines of having...
Inpatient palliative care patients often return to hospital Patients discharged from an inpatient...
Inpatient palliative care patients often return to hospital Patients discharged from an inpatient palliative care unit with a poor prognosis and limited survival often return to the hospital or emergency department, even though they have supports in place, according to a study in Journal of Palliative Medicine. Colleen Webber, PhD, at the Ottawa Hospital Research Institute in Ontario, Canada, was the lead author for the retrospective cohort study of medical records for 75 patients at one institution....
Antibacterial activity of new atraumatic restorative treatment materials incorporated with Azadirachta indica (Neem) against Streptococcus mutansPublication date: October–December 2019Source: Journal of Oral Biology and Craniofacial Research, Volume 9, Issue 4Author(s): P. Divya Kumari, Shilpa M. Shenoy, Shahnawaz Khijmatgar, Avidyuti Chowdhury, Edward Lynch, Chitta R. ChowdhuryAbstractBackgroundThe antibacterial property of new atraumatic restorative treatment (ART) materials incorporated with Azadirachta...
in a cohort of Sri LankansPublication date: October–December 2019Source: Journal of Oral Biology and Craniofacial Research, Volume 9, Issue 4Author(s): Manil C.N. Fonseka, P.V.Kalani S. Hettiarachchi, Rasika M. Jayasinghe, Ruwan D. Jayasinghe, C. Deepthi NanayakkaraAbstractObjectivesTo determine the size and position of the Greater Palatine Foramen using CBCTMaterials and methodGPF was evaluated on 50 CBCT's which were obtained at the Division of Oral Medicine and Radiology, FDS, University of Peradeniya,...
Proposed clinical definition for oral submucous fibrosis Publication date: October–December 2019Source: Journal of Oral Biology and Craniofacial Research, Volume 9, Issue 4Author(s): Chandramani B. More, Naman R. RaoAbstractOral Submucous Fibrosis (OSMF) is an insidious, chronic, complex, crippling, debilitating, irreversible, progressive, scarring, potentially malignant and collagen metabolic disorder, induced by a known carcinogen areca nut; wherein the oral mucosa, and occasionally the pharynx...
The interrelationship between urinary cotinine and nicotine dependence among tobacco users in an Indian de-addiction centre: A cohort pilot studyPublication date: October–December 2019Source: Journal of Oral Biology and Craniofacial Research, Volume 9, Issue 4Author(s): Nalini M. Vinoth Kumar, Shahnawaz Khijmatgar, Avidyuti Chowdhury, Martin Gootveld, Edward Lynch, Chitta ChowdhuryFactors influencing fluoride release in atraumatic restorative treatment (ART) materials: A reviewPublication date: October–December...
Patient Recruitment in Radiation Therapy Research: An Evaluation of Local ChallengesPublication date: Available online 18 July 2019Source: Journal of Medical Imaging and Radiation SciencesAuthor(s): Yobelli Alexandra Jimenez, Rachael Beldham-Collins, Sarah Jayne LewisAbstractIntroductionLocally-initiated research studies in radiation therapy (RT) aim to substantiate clinical processes and are an effective approach to gather evidence for advances in patient care, new techniques, and protocols. The...
Certain Textured Breast Implants by Allergan: Safety Communication - Due to an Increased Risk of Breast Implant-Associated Anaplastic Large Cell LymphomaAUDIENCE: Patient, Consumer, Health Professional, Surgery, Risk ManagerISSUE: The FDA requested that Allergan recall all BIOCELL textured breast implants and tissue expanders marketed in the U.S. based on newly submitted Medical Device Reports (MDRs) reporting worldwide cases of Breast Implant-Associated Anaplastic Large Cell Lymphoma (BIA-ALCL)...
Population Health: The Diabetes Educator's Evolving RoleTeresa L. Pearson, MS, RN, CDE, FAADE, Joan Bardsley, MBA, RN, CDE, FAADE, Susan Weiner, MS, RDN, CDE, FAADE, Leslie Kolb, MBA, RN, BSNFirst Published June 23, 2019; pp. 333–348AbstractHide PreviewPurposeThe US health care system's focus on high-quality, efficient, and cost-effective care has led payers and provider groups to identify new models with a shift toward value-based care. This perspective on clinical practice describes the population...
Challenges to Diabetes Self-Management in Emerging Adults With Type 1 DiabetesNeesha Ramchandani, PNP, CDE, Niobe Way, EdD, Gail D'Eramo Melkus, EdD, C-NP, FAAN, Susan Sullivan-Bolyai, DNSc, CNS, RN, FAANhttps://doi.org/10.1177/0145721719861349 | First Published July 13, 2019AbstractHide PreviewPurposeThe purpose of this qualitative descriptive study undergirded by Meleis's Transition Framework was to explore developmental, situational, and organizational challenges experienced by a diverse group...
C57BL/6 congenic mouse NRASQ61K melanoma cell lines are highly sensitive to the combination of Mek and Akt inhibitors in vitro and in vivo, Valérie Petit, Jeremy Raymond, Christophe Alberti, Marie Pouteaux, Stuart J. Gallagher, Mai Q. Nguyen, Andrew E. Aplin, Véronique Delmas, Lionel LarueVersion of Record online: 15 July 2019
Osteoblasts contribute to a protective niche that supports melanoma cell proliferation and survival, Jennifer Ferguson, Daniel J. Wilcock, Sophie McEntegart, Andrew P. Badrock, Mitch Levesque, Reinhard Dummer, Claudia Wellbrock, Michael P. SmithFirst Published: 19 July 2019ORIGINAL ARTICLESExtracellular acidosis triggers a senescence‐like phenotype in human melanoma cells,Ines Böhme, Anja BosserhoffFirst Published: 16 July 2019
How is the term haemangioma used in the literature? An evaluation against the revised ISSVA classification, Lloyd Steele MBChB, BMedSci, MRCP, Sarah Zbeidy MD, Jason Thomson MBBS, MA(Cantab), MSc, Carsten Flohr PhD, FRCP, FRCPCH, MPhil, MB, BCh, MScVersion of Record online: 18 July 2019BRIEF REPORTSPanniculitis in a 3‐year‐old child with Fanconi anemia‐associated bone marrow hypoplasia heralds transformation to acute myeloid leukemiaLucy Webber BMedSci, BM, MRCP, Michelle Cummins MBBS, MRCP, MRCPath, Rebecca...
Effectiveness of monovalent rotavirus vaccine against hospitalization with acute rotavirus gastroenteritis in Kenyan children Sammy Khagayi ; Richard Omore; Grieven P Otieno; Billy Ogwel; John B Ochieng ...
The Respiratory Modulation of Memory , Ludovic Molle and Charles-Étienne BenoitJournal of Neuroscience 24 July 2019, 39 (30) 5836-5838; DOI: https://doi.org/10.1523/JNEUROSCI.0224-19.2019
Michel Jeanneret (1940–2019), François Lecercle Nicholas Hewitt (1945–2019), Michael Kelly 'Les Français ne Savent Pas Où me Mettre': Placing Michaël Ferrier's Petits Portraits from Japan Hannah Holtzman Collage as form and Idea in the Art Criticism of Tristan Tzara Kathryn Brown
The Respiratory Modulation of Memory, Ludovic Molle and Charles-Étienne BenoitThe Journal of Neuroscience, 24 July 2019, 39(30):5836-5838; doi:10.1523/JNEUROSCI.0224-19.2019http://www.jneurosci.org/content/39/30/5836Perception and Cognition in Absolute Pitch: Distinct yet InseparableSimon Leipold, Marielle Greber and Stefan ElmerThe Journal of Neuroscience, 24 July 2019, 39(30):5839-5841; doi:10.1523/JNEUROSCI.0653-19.2019http://www.jneurosci.org/content/39/30/5839Research ArticlesCellular/MolecularSensory...
Nano‐WO3‐SO3H as a New Photocatalyst Insight Through Covalently Grafted Brønsted Acid: Highly Efficient Selective Oxidation of Benzyl Alcohols to AldehydesSaber Hosseini, Ali Amoozadeh, Yasaman AkbarzadehFirst Published: 16 July 2019Research ArticlesSensing Plant Physiology and Environmental Stress by Automatically Tracking Fj and Fi Features in PSII Chlorophyll Fluorescence InductionQian Xia, Jinglu Tan, Shengyang Cheng, Yongnian Jiang, Ya GuoFirst Published: 15 July 2019
Supply Chain Delays in Antimicrobial Administration After the Initial Clinician Order and Mortality in Patients With Sepsis,Objectives: There is mounting evidence that delays in appropriate antimicrobial administration are responsible for preventable deaths in patients with sepsis. Herein, we examine the association between potentially modifiable antimicrobial administration delays, measured by the time from the first order to the first administration (antimicrobial lead time), and death among people...
Photocatalytic Degradation of a Chlorinated Organic Chemical Using Activated Carbon Fiber Coupled...
Photocatalytic Degradation of a Chlorinated Organic Chemical Using Activated Carbon Fiber Coupled with Semiconductor, Ashitha Gopinath, Kadirvelu KrishnaVersion of Record online: 19 July 2019 A reusable photocatalyst developed based on activated carbon fibre and semiconductor was successfully utilized for degradation of 2, 4‐dichlorophenol which is priority pollutant listed by US EPA. Degradation efficiency of 94.3% was achieved when ratio of pollutant to Zn load was 1.37:1. Photogenerated holes...
The role of rehabilitation in patients with pulmonary arterial hypertension,Purpose of review The current review summarizes the latest evidence of the effects of exercise training for pulmonary hypertension patients demonstrated by six randomized controlled trails and 20 further studies. As the availability of exercise training is still limited it is important to raise awareness of the body of evidence showing the benefit for the patients and the limitations. Recent findings The effects of exercise...
Pathogenesis and complications of chronic eye rubbing in ocular allergy,Purpose of review To review the updated literature regarding eye rubbing complications and its association with ocular allergy disorders. Recent findings Atopy and ocular allergy disorders, mainly vernal keratoconjunctivitis (VKC), are strongly associated with rubbing-related complications, most probably via itching and watery eye sensations that trigger the habit of chronic eye rubbing. Vigorous and prolonged rubbing may lead...
The anti-oxidant roles of Taurine and Hypotaurine on acrosome integrity, HBA and HSPA2 of the human sperm during vitrification and post warming in two different temperaturePublication date: Available online 19 July 2019Source: CryobiologyAuthor(s): Mohammad Seify, Mahsa Zarabadipour, Leila Rashki Ghaleno, AliReza Alizadeh, Mojtaba Rezazadeh ValojerdiAbstractDespite advances in vitrification techniques for sperm cryopreservation, cryo-damages of sperm caused by generation of reactive oxygen species...
Urinary Stone Detection on CT Images Using Deep Convolutional Neural Networks: Evaluation of Model Performance and Generalization, A cascading convolutional neural network model, enriched with labeled CT images, detected the presence of urinary tract stones on unenhanced abdominopelvic CT scans with high accuracy (area under receiver operating characteristic curve, 0.954). Anushri Parakh, Hyunkwang Lee... Synho Do
Preclinical safety evaluation of the aqueous extract from Mangifera indica Linn. (Anacardiaceae): genotoxic, clastogenic and cytotoxic assessment in experimental models of genotoxicity in rats to predict potential human risksPublication date: 28 October 2019Source: Journal of Ethnopharmacology, Volume 243Author(s): Gustavo Roberto Villas Boas, João Marcos Rodrigues Lemos, Matheus William de Oliveira, Rafael Claudino dos Santos, Ana Paula Stefanello da Silveira, Flávia Barbieri Bacha, Caren Naomi...
Single-Cell RNA Sequencing Provides Insight Into Heart Development in MicePublished on Jul 24, 2019 DARPA Awards ASU $38.8M to Build Epigenetic-Based Device to Measure WMD ExposurePublished on Jul 24, 2019 Medulloblastoma Molecular Subtypes Refined With Single-Cell Transcriptome DataPublished on Jul 24, 2019Featured in Depth Dutch Startup Gen-X Offers Functional Genome Annotation ServicesPublished on Jul 24, 2019 Dutch Startup Cyclomics Developing Liquid Biopsy Assay Using Nanopore SequencingPublished...
Herbal Doctor Remedies Issues Voluntary Nationwide Recall of All Drug Products Due to Marketing Without FDA Approval and Concerns with Manufacturing Practices,Herbal Doctor Remedies is voluntarily recalling all drug products (see table below) within expiry to the consumer level. These products have been marketed without FDA approval and were manufactured outside of the controls required by current Good Manufacturing Practices (cGMP).These products could potentially result in risk to consumers as...
MEDICAL NEWS & PERSPECTIVES,Mounting Evidence and Netflix's Decision to Pull a Controversial Suicide SceneRebecca Voelker, MSJJAMA Psychiatry: Association of Increased Youth Suicides in the United States With the Release of 13 Reasons WhyQuick UptakesFor Mortality, Busting the Myth of 10 000 Steps per DayJennifer AbbasiJAMA Internal Medicine: Association of Step Volume and Intensity With All-Cause Mortality in Older WomenAuthor Interview: Association of Increased Youth Suicides With Release of 13...
Insights in Pediatric Research, Eleanor J. Molloy & Cynthia F. Bearer Pediatric Research 2019 86 :140 - 140; April 12, 2019; 10.1038/s41390-019-0394-8Abstract | Full TextCORRESPONDENCEProposed endocrine funding priorities for the NICHD strategic plan: expert opinion from the Pediatric Endocrine SocietyKanakadurga Singer, Michelle L. Katz & Steven D. Mittelman Pediatric Research 2019 86 :141 - 143; April 17, 2019; 10.1038/s41390-019-0401-0Abstract | Full TextCOMMENTAugust 2019 ECI biocommentaryMelissa...
Royal Society Publishing— Proceedings of the Royal Society BVol. 286, No. 1907, (July 2019) The above issue is now available online at:https://royalsocietypublishing.org/toc/rspb/2019/286/1907?ai=aqlf&ui=cbwb&af=HClick the links below to view the abstract for each article, or click the link above to view all Just Released articles for this journal.BehaviourResearch articles: Sun, age and test location affect spatial orientation in human foragers in rainforestsHaneul Jang , Christophe Boesch, Roger...
American Journal of Roentgenology, Medical Physics and InformaticsOriginal ResearchRadiation Dose for Multiregion CT Protocols: Challenges and LimitationsRamandeep Singh, et al. | American Journal of Roentgenology | Jul 24, 2019Ahead of PrintNuclear Medicine and Molecular ImagingOriginal ResearchIdentification of Axillary Lymph Node Metastasis in Patients With Breast Cancer Using Dual-Phase FDG PET/CTShinsuke Sasada, et al. | American Journal of Roentgenology | Jul 24, 2019Ahead of PrintSpecial ArticlesTechnical...
Using Longitudinal Milestones Data and Learning Analytics to Facilitate the Professional Development of Residents: Early Lessons from Three SpecialtiesPurpose: To investigate the effectiveness of using national, longitudinal milestones data to provide formative assessments to identify residents at risk of not achieving recommended competency milestone goals by residency completion. The investigators hypothesized that specific, lower milestone ratings at earlier time points in residency would be predictive...
Mid-term repair durability after MitraClip implantation in patients with functional mitral regurgitationBackground The aim of this study was to identify variables that are associated with the durability of percutaneous repair of secondary mitral regurgitation at 6-month follow-up. Methods and results Thirty-five consecutive patients with functional mitral regurgitation scheduled for MitraClip implant were enrolled. Left ventricular (LV) volumes and function and mitral valve characteristics were assessed...
Oral OncologyAvailable online 24 July 2019In Press, Corrected ProofWhat are Corrected Proof articles?Oral OncologyLetter to the editorFigures (2)Author links open overlay panelSameep S.ShettyHealth Care Global Enterprises Ltd, Bangalore 560027, IndiaManipal College of Dental Sciences, Mangalore 575001, IndiaLight House Hill Road Manipal Academy of Higher Education, IndiaAuthor links open overlay panelAkshayKudpajeHead and Neck Oncologist, Health Care Global Enterprises Ltd, Bangalore, IndiaAuthor...
Correlation Between Electroencephalography and Automated Pupillometry in Critically Ill Patients: A Pilot Study,Background: Electroencephalography (EEG) is widely used in the monitoring of critically ill comatose patients, but its interpretation is not straightforward. The aim of this study was to evaluate whether there is a correlation between EEG background pattern/reactivity to stimuli and automated pupillometry in critically ill patients. Methods: Prospective assessment of pupillary changes to...
Erector Spinae Plane Block For Postoperative Analgesia in Lumbar Spine Surgery: Is There a Better Option?No abstract availableGeneral Anesthetic Agents Are Not Neuroprotective and May be NeurotoxicNo abstract availableIn Remembrance of Hiroshi Takeshita, MD, Pioneering NeuroanesthesiologistNo abstract availableCorrelation Between Electroencephalography and Automated Pupillometry in Critically Ill Patients: A Pilot StudyBackground: Electroencephalography (EEG) is widely used in the monitoring of critically...
Predictive Validity of the CRAFFT for Substance Use Disorder,Rohit P. Shenoi, James G. Linakis, Julie R. Bromberg, T. Charles Casper, Rachel Richards, Michael J. Mello, Thomas H. Chun, Anthony Spirito and PEDIATRIC EMERGENCY CARE APPLIED RESEARCH NETWORKSpecial ArticleWhen Parents Take Conflicts to Digital MediaBryanna Moore and John D. Lantos
Featured Job of the Week,Internal Medicine — Florida Memorial Healthcare System, a leading 1,900-bed healthcare system located in South Florida, is seeking a BE/BC internal medicine physician for employment in one of its many primary care clinics spread throughout southern Broward County. The successful candidate must exhibit strong interpersonal and professional skills, have an understanding and willingness to practice in a family- and patient-centered care environment, and have an interest in...
IMAGES IN CLINICAL MEDICINENicola Dentale, M.D., Ph.D., and Rocco Trisolini, M.D.A 63-year-old man presented to the pulmonary clinic with a 3-month history of worsening dry cough and exertional dyspnea. He had a history of infection with the human immunodeficiency virus and had been receiving prescribed antiretroviral treatment intermittently for several years. His CD4 count was 81 cells per cubic millimeter. Expiratory wheezing was noted on lung auscultation. Computed tomography of the chest revealed...
Teaching TopicMeaslesCLINICAL PRACTICEMeaslesP.M. Strebel and W.A. Orenstein All cases of suspected measles should be reported immediately — without waiting for diagnostic test results — to the local or state health department, which can assist with obtaining tests and take actions to minimize spread of virus. United States travelers to other countries account for a high proportion of imported cases of measles, which emphasizes the importance of measles vaccination of U.S. residents who...
A Multicenter Trial of Vena Cava Filters in Severely Injured Patients, K.M. Ho and OthersN Engl J Med 2019;381:328-337 | Published Online July 7, 2019Teaching TopicVena Cava Filters in Severely Injured PatientsORIGINAL ARTICLEA Multicenter Trial of Vena Cava Filters in Severely Injured PatientsK.M. Ho and OthersCME Exam Quick Take The use of vena cava filters has become widespread in many trauma centers as a primary means to prevent pulmonary embolism in patients who are at high risk for bleeding....
A 48-year-old man presented to the dermatology clinic with a 6-month history of painful hand ulcerations and shortness of breath. He has no muscle weakness or arthritis. What is the diagnosis?CREST syndrome17% Anti-MDA5 dermatomyositis34% Pyoderma gangrenosum16% Cutaneous polyarteritis nodosa19% Behcet's disease13% Back to Poll8916 Total Responseshttps://www.nejm.org/image-challenge?ci=20190725&query=TOC
Health Care Autonomy of Women Living with HIVR.R. Redfield and OthersDOI: 10.1056/NEJMp1908843 | July 24, 2019Combating EPA Rollbacks — Health Care's Response to a Retreat on ClimateG. McCarthy and A. BernsteinDOI: 10.1056/NEJMp1909643 | July 24, 2019The Opportunity of CBD — Reforming the LawP.A. Cohen and J. SharfsteinN Engl J Med 2019;381:297-299 | Published Online June 12, 2019Implications of an Aging Rural Physician WorkforceL. Skinner, D.O. Staiger, D.I. Auerbach, and P.I. BuerhausN Engl J Med...
A Woman with Palpitations, Abdominal Pain, and VomitingA 39-year-old woman with cyclic vomiting syndrome and polysubstance use disorder presented with abdominal pain and agitation. In the emergency department, she had a sudden episode of tachycardia with a narrow QRS complex, with a heart rate of more than 200 beats per minute. What is the most likely diagnosis?Presentation of CaseDr. Kelsey Hills-Evans (Medicine): A 39-year-old woman with cyclic vomiting syndrome and polysubstance use disorder was...
Blueberry intake included in hypocaloric diet decreases weight, glucose, cholesterol, triglycerides and adenosine levels in obese subjectsPublication date: September 2019Source: Journal of Functional Foods, Volume 60Author(s): María Fernanda Higuera-Hernández, Elena Reyes-Cuapio, Marissa Gutiérrez-Mendoza, Henning Budde, Carlos Blanco-Centurión, André Barciela Veras, Nuno Barbosa Rocha, Tetsuya Yamamoto, Diogo Monteiro, Jaime Zaldívar-Rae, Dalila Aldana-Aranda, Sérgio Machado, Eric Murillo-RodríguezAbstractObesity...
Curcumin metabolism by human intestinal bacteria in vitroPublication date: October 2019Source: Journal of Functional Foods, Volume 61Author(s): Toshio Niwa, Shin-ichiro Yokoyama, Mika Mochizuki, Toshihiko OsawaAbstractWe tried to isolate metabolite in curcumin by incubation with human feces in vitro for the better understanding of curcumin activity in vivo. One group containing some bacteria, referred as 1C, produced a metabolite other than tetrahydrocurcumin. Structural analysis revealed that this...
The Adsorption Behavior of Atrazine in Common Soils in Northeast ChinaAbstractThe objective of this study was to evaluate the adsorption capacity of atrazine and the effects of different environmental conditions such as temperature, pH, Ca2+ and biochar on the adsorption characteristics of atrazine in different types of soil using the intermittent adsorption method. The kinetic experiment showed that the adsorption of atrazine in albic, black and saline–alkaline soils reached equilibrium within 24 h....
Commentary to: Prospective comparative study on the effects of lidocaine on urodynamic and sensory parameters in bladder-pain syndromeCommentary on: "Does spinal anesthesia lead to postoperative urinary retention in same day urogynecology surgery: a retrospective review"Treatment of subacute rectosigmoid obstruction secondary to uterosacral ligament suspensionThe transition from resident to consultantA live porcine model for robotic sacrocolpopexy trainingAbstractIntroduction and hypothesisRobotic...
Archaeologies of the British in Latin AmericaHistorical Archaeology and EnvironmentDaniel G. Roberts Award for Excellence in Public Historical Archaeology: The U.S. Forest Service Passport in Time ProgramHistorical Archaeology of Early Modern Colonialism in Asia-Pacific: The Southwest Pacific and Oceanian RegionsThe Shore is a Bridge: The Maritime Cultural Landscape of Lake OntarioJohn L. Cotter Award in Historical Archaeology: John M. ChenowethHaven to the East, Haven to the North: Great Barrington...
Probiotic Supplementation Decreases Chemotherapy-induced Gastrointestinal Side Effects in Patients With Acute Leukemia,Introduction: In children with acute leukemia, gut microbiota is modified secondary to chemotherapy administration, leading to gastrointestinal side effects. Probiotics are microorganisms that can restore gut microbiota and may help alleviate gastrointestinal symptoms. The aim of this pilot study was to assess the effects of probiotic supplementation on chemotherapy-induced gastrointestinal...
Metabolic Changes in Children that Received Chemotherapy,Cancer treatments are associated with short and long-effects. Epidemiological reports have revealed clinical features of metabolic syndrome (MS), obesity or overweight in young cancer survivors. The aim of the study was to examine the prevalence of unhealthy weight status and risk factors associated with MS related to chemotherapy. We study 52 pediatric cancer patients and analyze cholesterol, triglycerides, glycosylated hemoglobin, body mass...
Maintenance Therapy in Metastatic Solid Tumors: Innovative Strategy or Simple Second-line Treatment?Managing metastatic diseases involves defining the best strategy that is supposed to take into account both efficacy and quality of life. To this end, clinicians use stop and go or maintenance strategies. As a matter of fact, 2 maintenance strategies can be distinguished: continuation maintenance using a drug already present in induction treatment and switch maintenance with a newly introduced drug....
Combined Intermittent Pneumatic Leg Compression and Pharmacological Prophylaxis for Prevention of Venous Thromboembolism
Engage Your Core: Excellence in ResearchNo abstract availableWriting for Publication: Your Professional JourneyNo abstract availableLetter to the EditorNo abstract availableKeeping Up With Current Orthopaedic Nursing Practice: Results of the ONCB 2016 Role Delineation StudyBACKGROUND: The Orthopaedic Nurses Certification Board (ONCB) conducts a role delineation study (RDS), also known as a job task analysis, every 5 years. Results identify tasks performed by orthopaedic registered nurses and nurse...
Presbyphagia Versus Dysphagia: Normal Versus Abnormal Swallowing Symptoms in Older Adults With Parkinson Disease and Multiple Sclerosis,The purpose of this article is to describe normal, age-related changes in the swallowing mechanism, clinically referred to as "presbyphagia." The authors compare presbyphagia in the oral, pharyngeal, and esophageal phases of the swallow to abnormal, or impaired swallowing, termed "dysphagia." This article focuses on how older persons with Parkinson disease and multiple...
Foreword: Aging With a Progressive Neurologic Condition-Implications for RehabilitationNo abstract availableAging With a Progressive Neurologic Disease: Rehabilitation Management of the Adult Aging With Parkinson Disease or Multiple SclerosisThe confluence of an aging population and increasing life expectancy of people with neurodegenerative diseases such as Parkinson disease and multiple sclerosis means that there is a growing segment of the population who are aging with a neurodegenerative disease....
Folate Supplementation for Methotrexate Therapy in Patients With Rheumatoid Arthritis: A Systematic Review,Objective To review the evidence for benefits and harms of folate (folic acid or folinic acid) supplementation on methotrexate (MTX) treatment for rheumatoid arthritis (RA), to assess whether or not folate supplementation would reduce MTX toxicity or reduce MTX benefits, and to decide whether a higher MTX dosage is essential. Methods We performed a sensitive search strategy and searched systematically...
Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis–Like Lupus Erythematosus,Background/Objective Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN)–like lupus erythematosus is a hyperacute and life-threatening form of cutaneous lupus erythematosus. Because of its rarity, little is known about this entity. We aimed to evaluate the clinical characteristics, laboratory findings, systemic manifestations, treatments, and outcome of SJS/ TEN-like lupus erythematosus. Methods We conducted...
Folate Supplementation for Methotrexate Therapy in Patients With Rheumatoid Arthritis: A Systematic ReviewObjective To review the evidence for benefits and harms of folate (folic acid or folinic acid) supplementation on methotrexate (MTX) treatment for rheumatoid arthritis (RA), to assess whether or not folate supplementation would reduce MTX toxicity or reduce MTX benefits, and to decide whether a higher MTX dosage is essential. Methods We performed a sensitive search strategy and searched systematically...
Contributors: Burnout and Resilience in Obstetrics and GynecologyNo abstract availableForeword: Burnout and Resilience in Obstetrics and GynecologyNo abstract availableBurnout in Obstetricians and GynecologistsProfessional burnout threatens all high-functioning professionals and affects not only the individual, but, by extension, the patients they serve. The characteristics that make someone competitive for medical school, residency, or successful in academics or practice, make us particularly vulnerable...
Pressure injuries: A nursing-sensitive indicator?No abstract availableDrug NewsNo abstract availableAdvice P.R.N.No abstract availableCan medications become harmful after the expiration date?No abstract availableBalancing academic freedom with academic dutyNo abstract availableClinical RoundsNo abstract availableNew Drugs 2019, part 3Abstract: This article reviews seven drugs recently approved by the FDA, including indications, precautions, adverse reactions, and nursing considerations.New Drugs...
Medicare Access and CHIP Reauthorization Act and Rural HospitalsThe cost of health care within the United States has continued to increase, whereas the quality of patient care has generally decreased in some areas. With the continued use of Medicare's former physician reimbursement algorithm, termed sustainable growth rate, national expenditures within the United States have been expected to increase 5.6% annually. To modernize the delivery and financing of care, Congress has introduced the Medicare...
Device Legislation...... Now Tread CautiouslyNo abstract availableThe Sinus Bone Graft— Third Edition 2019No abstract availableRidge Architecture Preservation Following Minimally Traumatic Exodontia Techniques and Guided Tissue RegenerationObjective: To compare hard-tissue healing after 3 exodontia approaches. Materials and Methods: Premolars of dogs were extracted: (1) flapless, (2) flap, and (3) flap + socket coverage with polytetrafluoroethylene (dPTFE) nonresorbable membrane (flap + dPTFE). Animals...
Cone-Beam Computed Tomography Evaluation of the Submandibular Fossa in a Group of Dental Implant Patients,Objective: In the mandibular posterior region, presurgical imaging can provide valuable information of anatomical variants. The aim of this study is to evaluate submandibular fossa anatomy in the posterior mandible using cone-beam computed tomography (CBCT) scans. Study Design: One hundred thirty-two preimplant CBCT examinations were used. Several morphometric measurements were performed in the...
Visual Abstracts (#VisualAbstract): A New Journal Initiative to Disseminate ResearchNo abstract availableEculizumab as Primary Therapy for Active Antibody-Mediated Rejection of Renal Allografts: A Matter of Timing, Severity, and Donor-Specific AntibodiesNo abstract availableUltrasound Molecular Imaging of Lymphocyte-endothelium Adhesion Cascade in Acute Cellular Rejection of Cardiac AllograftsBackground: Acute cellular rejection is one of the main reasons for graft failure after heart transplantation....
Treatment of Nasal Scars Caused by Skin Necrosis From Hyaluronic Acid Injections Using Stromal Vascular Fraction Gel, a Novel Fat Tissue–Derived Product,
Efficacy and Safety of 3 New Resilient Hyaluronic Acid Fillers, Crosslinked With Decreased BDDE, for the Treatment of Dynamic Wrinkles: Results of an 18-Month, Randomized Controlled Trial Versus Already Available ComparatorsBACKGROUND Three new hyaluronic acid (HA)-based fillers made of long chains crosslinked with reduced amounts of 1,4-butanediol diglycidyl ether (BDDE) were developed for the treatment of dynamic facial areas. Their resilience and increased stretching ability were optimized to...
Use of Autologous, Noncultured Melanocyte–Keratinocyte Transplantation in Patients With Stable Genital LeucodermaNo abstract availableA Closure Option for Sinuous Hairline Preservation on the Upper ForeheadNo abstract availableSharp Debulking and Nonbeveled Layers in Mohs Micrographic Surgery, A Video Walkthrough: How We Do ItNo abstract availableVulvar Lichen Sclerosus: Consider Treatment With Heterologous Type I CollagenNo abstract availableEfficacy, Patient-Reported Outcomes, and Safety in Male...
Efficacy, Patient-Reported Outcomes, and Safety in Male Subjects Treated With OnabotulinumtoxinA for Improvement of Moderate to Severe Horizontal Forehead LinesBACKGROUND Men represent a growing segment of the facial aesthetic market. OBJECTIVE To evaluate investigator-assessed efficacy, patient-reported outcomes, and safety after onabotulinumtoxinA treatment of forehead lines (FHL) in men. METHODS Subjects with moderate to severe FHL received onabotulinumtoxinA (frontalis: 20 U; glabellar complex:...
Guide for the perplexed to the Shockley–Queisser model for solar cells pp501 - 505 Jean-Francois Guillemoles, Thomas Kirchartz, David Cahen & Uwe Rau doi:10.1038/s41566-019-0479-2 In memory of Mikhail Gorodetsky pp506 - 508 Igor Bilenko, Vladimir Ilchenko, Farid Khalili & Tobias J. Kippenberg doi:10.1038/s41566-019-0490-7 NEWS & VIEWSStriving for extreme solitons pp509 - 511 Benjamin Wetzel & Fetah Benabid doi:10.1038/s41566-019-0497-0 T-ray modulation of light for future...
Career gatekeeping in cultural fieldsAbstractThis paper presents a comparative analysis of career gatekeeping processes in two cultural fields. Drawing on data on appointment procedures in German academia and booking processes in North American stand-up comedy, we compare how gatekeepers in two widely different contexts evaluate and select candidates for established positions in their respective field and validate their decisions. Focusing on three types of gatekeeping practices that have been documented...
Inspecting the Foundation of Mystery House,John Aycock, Katie BiittnerIssued Date: 24 Jul 2019AbstractComputer games are recent artifacts that have had, and continue to have, enormous cultural impact. In this interdisciplinary collaboration between computer science and archaeology, we closely examine one such artifact: the 1980 Apple II game Mystery House, the first graphical adventure. We focus on implementation rather than gameplay, treating the game as a digital artifact. What can we learn about...
Amniotic band syndrome with Tessier number 4 and 7 clefts: a case report, Author links open overlay...Amniotic band syndrome with Tessier number 4 and 7 clefts: a case report,Author links open overlay panelZ.YangStomatological Hospital, Southern Medical University, Guangzhou 510280, ChinaAuthor links open overlay panelQ.LiangK.OuyangZ.PiaoKey Laboratory of Oral Medicine, Guangzhou Institute of Oral Disease, Stomatology Hospital of Guangzhou Medical University, Guangzhou 510140, ChinaAvailable online...
So from Here Where Do We Go? A Focus on the Sexuality of Women with Disabilities in Africa: A Narrative ReviewAbstractThis article is a narrative review of literature pertaining to the sexuality of women with disabilities in Africa. The review was undertaken through searching electronic databases namely, CINAHL, African e-Journals, MEDLINE, JSTOR, PubMed, and Web of Science; a general internet search was also undertaken. Focus was mainly on literature written in English over the past three decades...
Statins for Primary Prevention in Those Aged 70 Years and Older: A Critical Review of Recent Cholesterol GuidelinesAbstractThe risk of atherosclerotic cardiovascular disease rises with age and remains the leading cause of death in older adults. Evidence for the use of statins for primary prevention in older adults is limited, despite the possibility that this population may derive significant clinical benefit given its increased cardiovascular risk. Until publication of the 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA...
Intellectual Humility and Owning One's LimitationsAbstractIntellectual humility is a worthwhile virtue. Whitcomb et al. (Philos Phenomenol Res 94(3):520, 2017) recently propose a novel account of intellectual humility. According to this account, intellectual humility consists of proper attentiveness to and owning of one's intellectual limitations. We argue that this account is in accordance with empirical work on intellectual humility, but it has two problems. It leaves open the possibility that...
Time-Out and Distraction: Performing Checklists After the Plane Has Taken OffNo abstract availableVentilator Mode Does Not Influence Blood Loss or Transfusion Requirements During Major Spine Surgery: A Retrospective StudyBACKGROUND: Blood loss during adult spinal deformity surgery is multifactorial. Anesthetic-related factors, such as mode of mechanical ventilation, may contribute to intraoperative blood loss. The aim of this study was to determine the influence of ventilator mode and ventilator...
Understanding Intravitreal Silicone Oil Droplets Due to Intravitreal InjectionsNo abstract availableATYPICAL MACULAR HOLESPurpose: To study the etiology, clinical features, management options, and visual prognosis in various types of atypical macular holes (MHs). Methods: A review of the literature was performed, which focused on the etiopathogenesis of atypical or secondary MHs, their differentiating clinical features, management strategies, and varied clinical outcomes. Idiopathic or age-related,...
Treating Persons Who Inject Drugs: The Need for Holistic and Respectful CareNo abstract availableAre You Following Your Reimbursement "Playbook"?No abstract availableNonviral Injection-Related Injuries in Persons Who Inject Drugs: Skin and Soft Tissue Infection, Vascular Damage, and WoundsGENERAL PURPOSE To explore skin and soft-tissue infections and vascular damage in persons who inject drugs and relate these changes to wound development and care. TARGET AUDIENCE This continuing education activity...
Histopathology of Cutaneous AgingAbstract: Aging is (so far) an inexorable and irreversible path in all species and organisms. In human beings, aging involving the skin has a special meaning because our appearance has become crucial for our social life in the modern world. Knowledge of the morphologic changes that happen during the aging process is crucial for understanding its pathogenesis, which in turn is necessary to approach it and even revert it. Skin aging happens because of 2 main sets of...
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