Σάββατο, 27 Ιουλίου 2019

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,


Update on treatment options for blast-induced hearing loss  Purpose of review The incidence of blast...
Update on treatment options for blast-induced hearing loss Purpose of review The incidence of blast injuries has increased, and the ear is the highest risk organ. Ear injury induced by blast exposure is important in both military and civilian conditions. The permanent hearing loss caused by blast exposure is associated with a decline in the quality of life. In this review, I describe recent therapeutic strategies for each of the ear pathologies caused by blast exposure. Recent findings For tympanic...
Αλέξανδρος Γ. Σφακιανάκης
2m
Triglycerides and endothelial function: molecular biology to clinical perspective Purpose of review...
Triglycerides and endothelial function: molecular biology to clinical perspectivePurpose of review Recently, a high level of triglycerides has attracted much attention as an important residual risk factor of cardiovascular events. We will review and show the mechanisms underlying the association of endothelial dysfunction with hypertriglyceridemia and present clinical evidence for a relationship between endothelial function and triglycerides. Recent findings Clinical studies have shown that hypertriglyceridemia...
Αλέξανδρος Γ. Σφακιανάκης
2m
Neuropsychology as a Method of Diagnosis and Treatment of Internet Addiction Objective: Nowadays, the...
Neuropsychology as a Method of Diagnosis and Treatment of Internet AddictionObjective: Nowadays, the widespread use of the internet has resulted in the creation of the phenomenon of addiction to the internet. Internet addiction constitutes a new kind of mental disorder that is caused by the excessive use of the internet to a point that it interferes with daily life. In our research, we detected and recorded the electrophysiological brain characteristics of addicted users. Materials and Methods: Our...
Αλέξανδρος Γ. Σφακιανάκης
3m
Combination of laser microdissection, 2D-DIGE and MALDI-TOF MS to identify protein biomarkers to predict...
Combination of laser microdissection, 2D-DIGE and MALDI-TOF MS to identify protein biomarkers to predict colorectal cancer spread  Chandra Kirana, Lifeng Peng, Rose Miller, John P. Keating, Corinne Glenn, Hongjun Shi, T. William Jordan, Guy J. Maddern & Richard S. Stubbs Clinical Proteomicsvolume 16, Article number: 3 (2019) | Download CitationAbstractBiomarkers are urgently required to support current histological staging to provide additional accuracy in stratifying colorectal cancer (CRC)...
Αλέξανδρος Γ. Σφακιανάκης
6m
Plasma lipoproteome in Alzheimer's disease: a proof-of-concept study   Danni Li, Fangying Huang, Yingchun...
Plasma lipoproteome in Alzheimer's disease: a proof-of-concept study   Danni Li, Fangying Huang, Yingchun Zhao, Peter W. Villata, Timothy J. Griffin, Lin Zhang, Ling Li & Fang Yu Clinical Proteomicsvolume 15, Article number: 31 (2018) | Download CitationAbstractBackgroundAlthough total plasma lipoproteome consists of proteins that have shown promises as biomarkers that can identify Alzheimer's disease (AD), effect sizes are modest. The objective of this study is to provide initial proof-of-concept...
Αλέξανδρος Γ. Σφακιανάκης
7m
Validation of a novel model for the early detection of hepatocellular carcinoma  Philip M. Hemken, Lori...
Validation of a novel model for the early detection of hepatocellular carcinoma  Philip M. Hemken, Lori J. Sokoll, Xiaoqing Yang, Jianliang Dai, Debra Elliott, Susan H. Gawel, Michael Lucht, Ziding Feng, Jorge A. Marrero, Sudhir Srivastava, Daniel W. Chan & Gerard J. Davis Clinical Proteomicsvolume 16, Article number: 2 (2019) | Download CitationAbstractBackgroundThe biomarkers alpha-fetoprotein (AFP) and protein induced by vitamin K absence/antagonist-II (PIVKA-II) may be useful for detecting...
Αλέξανδρος Γ. Σφακιανάκης
8m
Journal of the European Academy of Dermatology and Venereology   Volume 33, Issue 8  Pages: 1439-1617,...
Journal of the European Academy of Dermatology and Venereology  Volume 33, Issue 8  Pages: 1439-1617, e275-e309  August 2019Issue InformationIssue InformationPages: 1439-1444 | First Published: 25 July 2019COMMENTARIESNot everything is as it seems: commentary on 'Stereophotogrammetric three‐dimensional photography is an accurate and precise planimetric method for the clinical visualization and quantification of human papilloma virus‐induced skin lesions'M. Skerlev, S. Ljubojević Hadžavdić, M. Sirotković‐SkerlevPages:...
Αλέξανδρος Γ. Σφακιανάκης
10m
Investigating the Effect of Cochlear Synaptopathy on Envelope Following Responses Using a Model of the...
Investigating the Effect of Cochlear Synaptopathy on Envelope Following Responses Using a Model of the Auditory NerveAbstractThe healthy auditory system enables communication in challenging situations with high levels of background noise. Yet, despite normal sensitivity to pure tones, many listeners complain about having difficulties in such situations. Recent animal studies demonstrated that noise overexposure that produces temporary threshold shifts can cause the loss of auditory nerve (AN) fiber...
Αλέξανδρος Γ. Σφακιανάκης
12m
High-throughput lipidomic profiling of high-density lipoprotein from egg yolk (EYHDL): comparison...
High-throughput lipidomic profiling of high-density lipoprotein from egg yolk (EYHDL): comparison based on UPLC-MS/MS and GC–MSAbstractHigh-density lipoproteins from egg yolk (EYHDL), also called lipovitellenin, is the second largest constituent of egg yolk (EY), and possesses important functional properties in lipid metabolism for its high content of phospholipids. To better understand its lipid profile, a lipidomic analysis based on ultrahigh-performance liquid chromatography tandem mass spectrometry...
Αλέξανδρος Γ. Σφακιανάκης
13m
Acetabular and femoral reconstruction in total hip replacement for adult hip dysplasia: A technical...
Acetabular and femoral reconstruction in total hip replacement for adult hip dysplasia: A technical guide for surgeons in our environmentOlukemi Lawani, Michael Okunola, Imoniche Adeoye-Sunday, Charles AyekoloyeNigerian Journal of Orthopaedics and Trauma 2019 18(1):1-3Hip dysplasia is abnormal development of the hip joint resulting in joint incongruity and characterised by a shallow acetabulum, inadequate femoral head coverage and femoral and acetabular version abnormalities. Childhood hip dysplasia...
Αλέξανδρος Γ. Σφακιανάκης
13m
The pathology of solid organ xenotransplantation Purpose of review The use of genetically modified pigs...
The pathology of solid organ xenotransplantationPurpose of review The use of genetically modified pigs has resulted in prolonged xenograft organ survival, overcoming the initial barriers that lead to hyperacute rejection and immediate loss of the graft. The purpose of the present review is to revisit the xenogeneic response and the pathologic changes in the xenograft organ in the context of recent publications of large animal studies that highlight existing challenges. Recent findings Transgenic...
Αλέξανδρος Γ. Σφακιανάκης
14m
Living with cancer and multimorbidity: the role of primary care Purpose of review As more people live...
Living with cancer and multimorbidity: the role of primary carePurpose of review As more people live longer with cancer, the number of patients with cancer and multiple other chronic conditions (multimorbidity) has increased. The presence of multimorbidity impacts on all stages of cancer care, from prevention and early detection through to end of life care, but research into cancer and multimorbidity is in its infancy. This review explores the impact of multimorbidity on adults living with (and beyond)...
Αλέξανδρος Γ. Σφακιανάκης
14m
Parvimico materdei gen. et sp. nov.: A new platyrrhine from the Early Miocene of the Amazon Basin, Peru1...
Parvimico materdei gen. et sp. nov.: A new platyrrhine from the Early Miocene of the Amazon Basin, Peru1Publication date: September 2019Source: Journal of Human Evolution, Volume 134Author(s): Richard F. Kay, Lauren A. Gonzales, Wout Salenbien, Jean-Noël Martinez, Siobhán B. Cooke, Luis Angel Valdivia, Catherine Rigsby, Paul A. BakerAbstractThree field seasons of exploration along the Río Alto Madre de Dios in Peruvian Amazonia have yielded a fauna of micromammals from a new locality AMD-45, at ∼12.8°S....
Αλέξανδρος Γ. Σφακιανάκης
15m
Functional and Cardiovascular Measurements in Patients With Peripheral Artery Disease: COMPARISON BETWEEN...
Functional and Cardiovascular Measurements in Patients With Peripheral Artery Disease: COMPARISON BETWEEN MEN AND WOMENPurpose: To compare functional and cardiovascular variables of men and women with peripheral artery disease (PAD). Methods: This observational, cross-sectional study included 67 women and 144 men (age 66 ± 9 and 67 ± 10 yr, respectively) with PAD. Patients were submitted to a clinical evaluation, 6-min walk test (6MWT) and cardiovascular evaluation, including blood pressure, arterial...
Αλέξανδρος Γ. Σφακιανάκης
17m
Real-world virological efficacy and safety of daclatasvir/asunaprevir/beclabuvir in patients with chronic...
Real-world virological efficacy and safety of daclatasvir/asunaprevir/beclabuvir in patients with chronic hepatitis C virus genotype 1 infection in JapanAbstractBackgroundThe virological efficacy and safety of the direct-acting antiviral (DAA) regimen consisting of daclatasvir, asunaprevir, and beclabuvir (DCV/ASV/BCV) for patients chronically infected with hepatitis C virus (HCV) genotype 1 have not been previously evaluated in Japanese real-world settings.MethodsIn a Japanese nationwide multicenter...
Αλέξανδρος Γ. Σφακιανάκης
18m
The efficacy of vonoprazan and proton-pump inhibitors for maintenance treatment of gastroesophageal reflux disease
Systematic review with network meta-analysis: indirect comparison of ...AbstractBackgroundLong-term maintenance treatment of gastroesophageal reflux disease (GERD) is important to prevent relapse. Proton-pump inhibitors (PPIs) are used for both treatment and maintenance therapy of GERD. Recently, a potassium-competitive acid blocker vonoprazan was launched in Japan. We evaluated the comparative efficacy of vonoprazan and other PPIs for GERD maintenance.MethodsA systematic literature search was performed...
Αλέξανδρος Γ. Σφακιανάκης
18m
A Helicobacter pylor i screening and treatment program to eliminate gastric cancer among junior high school students
 in Saga Prefecture: a preliminary reportAbstractBackgroundTo present the strategies and preliminary findings of the first 3 years after implementing a Helicobacter pylori screening and eradication program to prevent gastric cancer in Saga Prefecture.MethodsA screening and treatment program to eradicate H. pylori from third-grade junior high students was started in Saga Prefecture in 2016, using local governmental grants. Screening was with urinary anti-H. pylori antibody tests, followed by H. pylori stool...
Αλέξανδρος Γ. Σφακιανάκης
20m
Imatinib Induced Complete Remission of Psoriasis in a Patient with Chronic Myeloid Leukemia Clinical...
Imatinib Induced Complete Remission of Psoriasis in a Patient with Chronic Myeloid LeukemiaClinical Characteristics and Treatment Outcome of Hypocellular Acute Myeloid Leukemia Based on WHO ClassificationAbstractThe hypocellular acute leukemia is very rare atypical leukemia with frequency of 5–7% among patients with acute leukemias. It mainly occurs in older patients and usually has a myeloid phenotype. It is still unclear whether the outcome of hypocellular acute myeloid leukemia is less favorable...
Αλέξανδρος Γ. Σφακιανάκης
21m
The Innovator of Electrosurgery Hemostasis has been a major risk in the surgical field, causing Halsted...
The Innovator of ElectrosurgeryHemostasis has been a major risk in the surgical field, causing Halsted to preach for the need for better control of bleeding to improve the morbidity and mortality many surgeons faced at the time. This problem, while combated by suturing methods for many, remained an issue in the neurosurgical field. Dr. Cushing sought out the help of William Bovie, leading to the creation of electrosurgery. This invention changed the way surgery could be performed and remains to be...
Αλέξανδρος Γ. Σφακιανάκης
22m
Incidence of Pneumothorax Experienced After Orthognathic Surgery The purpose of this study is to...
Incidence of Pneumothorax Experienced After Orthognathic SurgeryThe purpose of this study is to evaluate the frequency of pneumothorax following orthognathic surgery and describe its clinical presentation. A retrospective analysis of a hospital database was carried out on consecutive patients with normal presurgical clinical assessment, laboratory findings, and chest X-ray who underwent orthognathic surgery from January 2007 to September 2018 in the Department of Oral and Craniomaxillofacial Surgery,...
Αλέξανδρος Γ. Σφακιανάκης
22m
Major Structural Airway Pathologies of Patient Complaining Nasal Obstruction  Analysis of Frequency,...
Major Structural Airway Pathologies of Patient Complaining Nasal Obstruction Analysis of Frequency, Preoperative Complaints, and Benefit From SurgeryKankaya, Yuksel MD; Ozer, Kadri MDJournal of Craniofacial Surgery: July 26, 2019 - Volume Publish Ahead of Print - Issue - pdoi: 10.1097/SCS.0000000000005790
Αλέξανδρος Γ. Σφακιανάκης
23m
Endonasal Endoscopic Management of Pterigopalatine Fossa Hydatid Cyst Hydatid cyst (echinococcosis)...
Endonasal Endoscopic Management of Pterigopalatine Fossa Hydatid CystHydatid cyst (echinococcosis) is an infectious disease caused mainly by Echinococcus granulosus, a parasite transmitted by dogs and encountered 1st in the liver and then in the lungs. Involvement in the head and neck region is uncommon, and pterygopalatine fossa disease resulting from hydatid cyst is extremely rare, with only 4 reported patients. In this report, the authors present a patient with exophthalmus caused by a primary...
Αλέξανδρος Γ. Σφακιανάκης
23m
Algorithm for selection of balance assessment tools in post-stroke patients The aim of the study was...
Algorithm for selection of balance assessment tools in post-stroke patientsThe aim of the study was to design an algorithm of selecting the balance assessment tool in patients after stroke, which could be used in a subacute rehabilitation setting. A retrospective study was carried out to analyse results of standardized balance measurements in three groups of stroke patients classified by Functional Ambulation Category (FAC) (FAC 1 or 2, non-functional ambulation; FAC 3 or 4, ambulatory dependent;...
Αλέξανδρος Γ. Σφακιανάκης
25m
Functional improvement after severe brain injury with disorder of consciousness paralleling treatment...
Functional improvement after severe brain injury with disorder of consciousness paralleling treatment for comorbid obstructive sleep apnoea: a case reportSurvivors of brain injury who have disorders of consciousness often have chronic functional deficits and disability. Obstructive sleep apnoea, a sleep-related breathing disorder, is a medical comorbid condition common among persons with brain injury and is injurious to health. Research on obstructive sleep apnoea treatment among brain-injured patients–particularly...
Αλέξανδρος Γ. Σφακιανάκης
25m
Unique MicroRNAs Signature of Lymphocyte of Yang and Yin Syndromes in Acute Ischemic Stroke Patients...
Unique MicroRNAs Signature of Lymphocyte of Yang and Yin Syndromes in Acute Ischemic Stroke PatientsAbstractObjectiveTo identify the differentially expressed microRNAs (miRNAs) profiles of yang and yin syndromes in patients with acute ischemic stroke, and to provide the molecular basis of the classification of these two syndrome types in acute ischemic stroke patients.MethodsA microarray assay was performed to assess the expression pattern of miRNAs in the lymphocyte of acute ischemic stroke patients....
Αλέξανδρος Γ. Σφακιανάκης
26m
Wandering spiders recover more slowly than web-building spiders after fire Abstract Fire is a natural...
Wandering spiders recover more slowly than web-building spiders after fireAbstractFire is a natural feature of many ecosystems, with some vegetation types highly adapted to fire. However, very little is known about the effect of fire on spiders, especially as fires have become more frequent owing to human activity. We determine whether different spider functional guilds (web builders vs. wanderers) respond differently to fires in the sclerophyllous fynbos. We determine also the effect of rockiness...
Αλέξανδρος Γ. Σφακιανάκης
33m
Thoracolumbar junction orientation: its impact on thoracic kyphosis and sagittal alignment in both asymptomatic...
Thoracolumbar junction orientation: its impact on thoracic kyphosis and sagittal alignment in both asymptomatic volunteers and symptomatic patientsAbstractPurposeThe thoracolumbar junction (TLJ) has not been explored in regard to its contribution to global sagittal alignment. This study aims to define novel sagittal parameters of the TLJ and to assess their roles within global sagittal alignment.MethodsIncluded for cross-sectional, retrospective analysis were asymptomatic volunteers and symptomatic...
Αλέξανδρος Γ. Σφακιανάκης
33m
Neanderthal Population Dynamics Clarified With New Sequence Data Jun 26, 2019 | staff reporter Save...
Neanderthal Population Dynamics Clarified With New Sequence DataJun 26, 2019 | staff reporterSave for laterNEW YORK – A team from Germany and Belgium has sequenced two new Neanderthal genomes to untangle the ancient history of the ancient hominins.As they reported online today in Science Advances, investigators at the Max Planck Institute for Evolutionary Anthropology and elsewhere sequenced nuclear DNA from two Neanderthals whose remains were dated to about 120,000 years ago. The Neanderthals —...
Αλέξανδρος Γ. Σφακιανάκης
36m
Brain Evolution by Design  Read the sample chapter: Insect Brains: Minute Structures Controlling Complex...
Brain Evolution by Design Read the sample chapter: Insect Brains: Minute Structures Controlling Complex Behaviors
Αλέξανδρος Γ. Σφακιανάκης
37m
Fathers' and Mothers' Early Mind-Mindedness Predicts Social Competence and Behavior Problems in Childhood...
Fathers' and Mothers' Early Mind-Mindedness Predicts Social Competence and Behavior Problems in ChildhoodAbstractParental mind-mindedness, the parent's propensity to treat the child as an intentional agent, has repeatedly shown to promote children's development of social understanding and secure attachment. Less is known about whether the impact of maternal and paternal mind-mindedness extends to children's social and behavior problems. We investigated the combined effect of mothers' and fathers'...
Αλέξανδρος Γ. Σφακιανάκης
38m
Planar Lens–Based Ultra-Wideband Dielectric Rod Waveguide Antenna for Tunable THz and Sub-THz Photomixer...
Planar Lens–Based Ultra-Wideband Dielectric Rod Waveguide Antenna for Tunable THz and Sub-THz Photomixer SourcesAbstractIn this manuscript, the use of dielectric rod waveguide antenna (DRW) with an embedded planar lens is proposed as a highly directional alternative to an electrically large hyper-hemispheric silicon lens for emission at millimeter and sub-millimeter wave frequencies. DRW antennas radiate properly if only the fundamental mode is excited to the structure. Since photomixer-based terahertz...
Αλέξανδρος Γ. Σφακιανάκης
38m
Association between invasively measured aortic pulse pressure and orthostatic hypotension in patients...
Association between invasively measured aortic pulse pressure and orthostatic hypotension in patients undergoing invasive coronary angiographyObjective: Underlying pathophysiology of orthostatic hypotension has been poorly understood. We hypothesized that aortic pulse pressure (APP) reflecting aortic stiffness may be involved in the development of orthostatic hypotension. Methods: A total of 200 patients (age 64.3 ± 10.9 years, 62.5% men) who underwent invasive coronary angiography (ICA) were prospectively...
Αλέξανδρος Γ. Σφακιανάκης
39m
'Reader, I married him/her': Ali Smith, Ovid, and queer translation ,  Holly Ranger This essay frames...
'Reader, I married him/her': Ali Smith, Ovid, and queer translation ,  Holly RangerThis essay frames Ali Smith's novel Girl meets boy (2007) as a 'queer translation' of Ovid, Metamorphoses 9.666-797. I argue that Smith's presentation of a contemporary genderqueer Iphis and Ianthe not only fictionalizes the critical argument proposed by Judith Butler's Gender Trouble, but uses Gender Trouble as a queer translation manifesto. Reading Girl meets boy through this Butlerian lens, which foregrounds multiplicity...
Αλέξανδρος Γ. Σφακιανάκης
42m
One man and his dog: Umberto D  Poverty is bad for the health of older people, as for others. It may...
One man and his dog: Umberto D Poverty is bad for the health of older people, as for others. It may be particularly bad for mental health and, while obviously not the only factor, changes in poverty rates have been strongly associated with the rising suicide rates in the United States (and falling global rates worldwide) in recent years [1, 2]. Loss of dignity is among the most harmful characteristics of poverty. Owning a pet may be good for the mental health of, and protective against loneliness...
Αλέξανδρος Γ. Σφακιανάκης
43m
A recent essay by poet laureate Tracy K. Smith contends that, through the 1990s, American poetry was...
A recent essay by poet laureate Tracy K. Smith contends that, through the 1990s, American poetry was gripped by a "firm admonition to avoid composing political poems," but with the shock of 9/11 and the ensuing war in Iraq, "something shifted in the nation's psyche" that sparked a renewed flowering of socially engaged political poetry. Three new critical monographs remind us, however, that, at least when it comes to war, poets have always been political. In their respective volumes, Tim Dayton, Rachel...
Αλέξανδρος Γ. Σφακιανάκης
44m
The call of the North   Sanna Raninen  Early English keyboard music revitalized   Andrew Woolley  A...
The call of the North   Sanna Raninen  Early English keyboard music revitalized   Andrew Woolley  A festival of Franciscans   Michael Talbot  Early modern elegies   Katherine Butler  Hildegard's extraordinary life   Marianne Richert Pfau  Florentine patricians, art, music and culture around 1600   Valerio Morucci  A harpsichordist's handbook   Thérèse de Goede
Αλέξανδρος Γ. Σφακιανάκης
45m
The Aura of Opera Reproduced: Fantasies and Traps in the Age of the Cinecast ,.  João Pedro Cachopo
The Aura of Opera Reproduced: Fantasies and Traps in the Age of the Cinecast ,.  João Pedro Cachopo
Αλέξανδρος Γ. Σφακιανάκης
45m
GuLF DREAM: A Model to Estimate Dermal Exposure Among Oil Spill Response and Clean-up Workers,   Melanie...
GuLF DREAM: A Model to Estimate Dermal Exposure Among Oil Spill Response and Clean-up Workers,   Melanie Gorman Ng; John W Cherrie; Anne Sleeuwenhoek; Mark Stenzel ; Richard K Kwok ...  Derivation of Time-Activity Data Using Wearable Cameras and Measures of Personal Inhalation Exposure among Workers at an Informal Electronic-Waste Recovery Site in Ghana  Zoey Laskaris; Chad Milando; Stuart Batterman; Bhramar Mukherjee; Niladri Basu ...
Αλέξανδρος Γ. Σφακιανάκης
46m
Is It Time to Reconsider the Group A Streptococcal Rheumatogenic Concept?
The Limitations of the Rheumatogenic Concept for Group A Streptococcus: Systematic Review and Genetic AnalysisGabrielle de Crombrugghe; Noemie Baroux; Anne Botteaux ; Nicole J Moreland; Deborah A Williamson ...Wide genetic distribution of group A streptococcus emm types was associated with acute rheumatic fever. Rheumatogenic motifs were infrequent. Microbiology studies on rheumatic fever pathogenesis should also examine previously called nonrheumatogenic emm types. Vaccine development should aim...
Αλέξανδρος Γ. Σφακιανάκης
48m

Songs of Silver Speech: "CareMusLy": Song Writing in the Treatment of Psychosis  Andrea Volpini Songwriting...
Songs of Silver Speech: "CareMusLy": Song Writing in the Treatment of Psychosis  Andrea VolpiniSongwriting is commonly utilized in the clinical treatment of psychiatric patients suffering from a wide variety of psychoses. CareMusLy (CML) is a psychodynamic, systematically applied intervention combining music and lyrics to counteract and redefine the problems created by the psychotic dimension. The process starts from a free collective vocal improvisation, during which the music therapist transcribes...
Αλέξανδρος Γ. Σφακιανάκης
49m
New chromosomal lineages within Microvirga andBradyrhizobium genera nodulate Lupinus angustifolius growing...
New chromosomal lineages within Microvirga andBradyrhizobium genera nodulate Lupinus angustifolius growing on different Tunisian soils  M Rejili; A Msaddak; I Filali; M A Benabderrahim; M Mars ...
Αλέξανδρος Γ. Σφακιανάκης
50m
Polyneuropathy in Critically Ill Mechanically Ventilated Children: Experience From a Tertiary Care Hospital...
Polyneuropathy in Critically Ill Mechanically Ventilated Children: Experience From a Tertiary Care Hospital in North IndiaObjectives: To determine the prevalence of critical illness polyneuropathy and its risk factors in critically ill children mechanically ventilated for 7 days or more. Design: Observational cohort study. Setting: PICU of a tertiary care hospital from North India. Patients: Children 1–15 years old admitted in PICU from June 2016 to September 2017, mechanically ventilated for 7 days...
Αλέξανδρος Γ. Σφακιανάκης
50m
The relationship between guarding, pain, and emotion Introduction: Pain-related behavior in people with...
The relationship between guarding, pain, and emotionIntroduction: Pain-related behavior in people with chronic pain is often overlooked in a focus on increasing the amount of activity, yet it may limit activity and maintain pain and disability. Targeting it in treatment requires better understanding of the role of beliefs, emotion, and pain in pain behavior. Objectives: This study aimed to clarify the interrelationships between guarding, pain, anxiety, and confidence in movement in people with chronic...
Αλέξανδρος Γ. Σφακιανάκης
51m
Cochlear Implant Outcomes in Large Vestibular Aqueduct Syndrome—Should We Provide Cochlear Implants...
Cochlear Implant Outcomes in Large Vestibular Aqueduct Syndrome—Should We Provide Cochlear Implants Earlier?Objective: Examine postoperative speech perception outcomes in a large vestibular aqueduct syndrome (LVAS) patients at a major cochlear implantation center. Study Design: Retrospective analysis of the Sydney Cochlear Implant Centre (SCIC) database and medical records from January 1994 to December 2015 was performed. Setting: Tertiary referral center. Patients: Patients with a diagnosis of LVAS...
Αλέξανδρος Γ. Σφακιανάκης
52m
Evidence of Prostate-Specific Membrane Antigen Expression in Hepatocellular Carcinoma Using 68Ga-PSMA...
Evidence of Prostate-Specific Membrane Antigen Expression in Hepatocellular Carcinoma Using 68Ga-PSMA PET/CTIntroduction Prostate specific membrane antigen (PSMA) expression has been demonstrated in tumor neovasculature of many solid tumors, including hepatocellular carcinoma (HCC). The purpose of this study is to evaluate PSMA expression in patients with HCC. Materials and Methods Nineteen HCC patients who underwent 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET) as part of restaging...
Αλέξανδρος Γ. Σφακιανάκης
53m
  Prostatic Artery Embolization for Benign Prostatic Hyperplasia: Patient Evaluation, Anatomy, and...
 Prostatic Artery Embolization for Benign Prostatic Hyperplasia: Patient Evaluation, Anatomy, and Technique for Successful Treatment  Prostatic artery embolization is emerging as an effective and safe treatment of symptomatic benign prostatic hyperplasia.   Andrew C. Picel, Tung-Chin Hsieh...Ari J. Isaacson
Αλέξανδρος Γ. Σφακιανάκης
56m
  Contrast-enhanced US in Local Ablative Therapy and Secondary Surveillance for Hepatocellular...
 Contrast-enhanced US in Local Ablative Therapy and Secondary Surveillance for Hepatocellular Carcinoma  The role of contrast-enhanced US in ablative therapy for hepatocellular carcinoma includes patient selection, treatment planning, intraprocedural guidance, and immediate postprocedural assessment; the authors also describe their use of this modality for secondary surveillance.   Sanjay Bansal, Jonathan Gui...Stephanie R. Wilson Invited Commentary on "Contrast-enhanced US in Local Ablative Therapy...
Αλέξανδρος Γ. Σφακιανάκης
57m
The Voices of Nîmes: Women, Sex, and Marriage in Reformation Languedoc,  Tom Hamilton  The Perraults:...
The Voices of Nîmes: Women, Sex, and Marriage in Reformation Languedoc,  Tom Hamilton  The Perraults: A Family of Letters in Early Modern France , Julie D Campbell  National Gallery Catalogues: The Eighteenth Century French Paintings,  Emma Barker
Αλέξανδρος Γ. Σφακιανάκης
57m
Théophile Gautier, Œuvres complètes, Romans, contes et nouvelles, iv: Le Capitaine Fracasse. Édition...
Théophile Gautier, Œuvres complètes, Romans, contes et nouvelles, iv: Le Capitaine Fracasse. Édition critique par Sarah Mombert  Michael Tilby  La Vraie Vie de Vinteuil. Par Jérôme Bastianelli  Jennifer Rushworth  Penser l'après Louis XIV: histoire, mémoire, représentation (1715–2015). Sous la direction de Sven Externbrink et Charles-Édouard Levillain  Michael Sonenscher  Le Double: littérature, arts, cinéma: nouvelles approches. Sous la direction de Erica Durante et Amaury Dehoux  Jules O'Dwyer
Αλέξανδρος Γ. Σφακιανάκης
58m
David Alan Johnson, Diploma Mill: The Rise and Fall of Dr. John Buchanan and the Eclectic Medical College...
David Alan Johnson, Diploma Mill: The Rise and Fall of Dr. John Buchanan and the Eclectic Medical College of Pennsylvania  Lynn E Miller  Medical Surveillance and Medical Confidentiality in an Age of Transition: The Debate over Cancer Registration in West Germany  Larry Frohman
Αλέξανδρος Γ. Σφακιανάκης
58m
Love and Money in the Informal Empire: The British in Argentina, 1830–1930,  Deborah Cohen
Love and Money in the Informal Empire: The British in Argentina, 1830–1930,  Deborah Cohen
Αλέξανδρος Γ. Σφακιανάκης
58m
Prescriptions on Demand: The Growth of Direct-to-Consumer Telemedicine Companies Tara Jain, BA; Richard...
Prescriptions on Demand: The Growth of Direct-to-Consumer Telemedicine CompaniesTara Jain, BA; Richard J. Lu, MBA; Ateev Mehrotra, MD, MPHJAMA DIAGNOSTIC TEST INTERPRETATIONInterpretation of Vitamin B12 Status After a Roux-en-Y Gastric BypassSameer B. Murali; MD MSHSEarn CME credit
Αλέξανδρος Γ. Σφακιανάκης
1h
OncologyEducation is proud to present our Best of ASCO Toronto 2019 Presentations. These videos incorporate...
OncologyEducation is proud to present our Best of ASCO Toronto 2019 Presentations.These videos incorporate perspectives from our faculty of experts.Please enjoy and share with your colleagues.To view the videos, click the images below:
Αλέξανδρος Γ. Σφακιανάκης
1h
The Longitudinal Association between Social Support on HIV Medication Adherence and Healthcare Utilization...
The Longitudinal Association between Social Support on HIV Medication Adherence and Healthcare Utilization in the Women's Interagency HIV StudyAbstractSocial support is associated with HIV-related health outcomes. However, few studies have explored this longitudinally. We assessed psychometric properties of the Medical Outcomes Study's Social Support Survey among women in the Women's Interagency HIV Study, and explored the longitudinal effects of social support on HIV medication adherence (HIV-positive...
Αλέξανδρος Γ. Σφακιανάκης
1h
Virtual Reality to Improve the Experience of the Mohs Patient—A Prospective Interventional Study BACKGROUND...
Virtual Reality to Improve the Experience of the Mohs Patient—A Prospective Interventional StudyBACKGROUND Nonmelanoma skin cancer is the most common cancer in the United States with significant quality of life impact. OBJECTIVE To assess the utility of a highly immersive virtual reality (VR) experience in the context of outpatient skin cancer surgery as a means to minimize patient-reported feelings of anxiety or pain. The authors also sought to assess the effects on patient-reported overall satisfaction....
Αλέξανδρος Γ. Σφακιανάκης
1h
Robotic cholecystectomy for acute cholecystitis: Three case reports Introduction: Nowadays laparoscopic...
Robotic cholecystectomy for acute cholecystitis: Three case reportsIntroduction: Nowadays laparoscopic cholecystectomy is considered as criterion standard for surgical treatment of acute calculous cholecystitis. During the last few years, there has been growing interest about the robotic approach. Several authors have reported the superiority of robotic cholecystectomy, associated with a lower percentage of conversion especially in patients with intraoperative diagnosis of acute or gangrenous cholecystitis....
Αλέξανδρος Γ. Σφακιανάκης
1h
Thyroid cartilage loci and hyoid bone analysis using a video fluoroscopic swallowing study (VFSS) ...
Thyroid cartilage loci and hyoid bone analysis using a video fluoroscopic swallowing study (VFSS)Introduction: Hyoid bone movement can be useful for diagnosing oropharyngeal dysphagia. In most clinical settings, the movement can be evaluated by a video fluoroscopic swallowing study (VFSS) that induces radiation exposure. In contrast with the hyoid bone, the thyroid cartilage is easily seen through the anterior neck surface. We hypothesized that the movement of thyroid cartilage correlates with hyoid...
Αλέξανδρος Γ. Σφακιανάκης
1h
E-cadherin expression is associated with susceptibility and clinicopathological characteristics of...
E-cadherin expression is associated with susceptibility and clinicopathological characteristics of thyroid cancer: A PRISMA-compliant meta-analysisBackground: Recently, many studies have been carried out to investigate the clinicopathological significance of E-cadherin expression in thyroid cancer. However, the results remained inconsistent. In the present study, we performed a meta-analysis to evaluate the associations of E-cadherin expression with susceptibility and clinicopathological characteristics...
Αλέξανδρος Γ. Σφακιανάκης
1h
A Unique Partnership to Bolster Public Health Practice No abstract available Factors Associated With...
A Unique Partnership to Bolster Public Health PracticeNo abstract availableFactors Associated With Continuous Improvement by Local Boards of HealthBackground: The continuous improvement function, 1 of the 6 public health governance functions, can be usefully applied in the context of local boards of health (LBoHs) operations to target self-improvements. Purpose: The purpose of this study was to determine the engagement level of LBoHs in continuous improvement efforts and to identify factors associated...
Αλέξανδρος Γ. Σφακιανάκης
1h

Lactic Acidosis and The Role of Sodium Bicarbonate: A Narrative Opinion Lactic acidosis occurs commonly...
Lactic Acidosis and The Role of Sodium Bicarbonate: A Narrative OpinionLactic acidosis occurs commonly and can be a marker of significant physiologic derangements. However what an elevated lactate level and acidemia connotes and what should be done about it is subject to inconsistent interpretations. This review examines the varied etiologies of lactic acidosis, the physiologic consequences, and the known effects of its treatment with sodium bicarbonate. Lactic acidosis is often assumed to be a marker...
Αλέξανδρος Γ. Σφακιανάκης
1h
Stem Cell Therapy and Hydrogen Sulfide: Conventional or Nonconventional Mechanisms of Action? Purpose:...
Stem Cell Therapy and Hydrogen Sulfide: Conventional or Nonconventional Mechanisms of Action?Purpose: Hydrogen sulfide (H2S) has many beneficial biological properties, including the ability to promote vasodilation. It has been shown to be released from stem cells and increased by hypoxia. Therefore, H2S may be an important paracrine factor in stem cell mediated intestinal protection. We hypothesized that hydrogen sulfide created through conventional pathways would be a critical component of stem...
Αλέξανδρος Γ. Σφακιανάκης
1h
Pediatric Respiratory Illness Measurement System (PRIMES) Scores and Outcomes Rita Mangione-Smith,...
Pediatric Respiratory Illness Measurement System (PRIMES) Scores and OutcomesRita Mangione-Smith, Chuan Zhou, Derek J. Williams, David P. Johnson, Chén C. Kenyon, Amy Tyler, Ricardo Quinonez, Joyee Vachani, Julie McGalliard, Joel S. Tieder, Tamara D. Simon, Karen M. Wilson and for the Pediatric Research in Inpatient Settings (PRIS) NetworkSpecial ArticleA Framework for Evaluation of the Higher-Risk Infant After a Brief Resolved Unexplained EventJ. Lawrence Merritt II, Ricardo A. Quinonez, Joshua...
Αλέξανδρος Γ. Σφακιανάκης
1h
Antimicrobial Activity of Biosynthesized Silver Nanoparticles Decorated Silica Nanoparticles Abstract...
Antimicrobial Activity of Biosynthesized Silver Nanoparticles Decorated Silica NanoparticlesAbstractThe production of cheap and effective compound for medicinal application is a major challenge for scientific community. So, several biological materials have been explored for the possible application in material synthesis which are useful in biomedical uses. Here, biomolecules from green tea leaves were functionalized on the surface of silicon dioxide nanoparticles (GSiO2 NPs). Next, the decoration...
Αλέξανδρος Γ. Σφακιανάκης
1h
The Effect of Maternity Leave Expansions on Fertility Intentions: Evidence from Switzerland Abstract...
The Effect of Maternity Leave Expansions on Fertility Intentions: Evidence from SwitzerlandAbstractWe study the effect of the expansion of the mandatory paid maternity leave, implemented in Switzerland in 2005, on individuals' fertility intentions. Earlier literature found evidence of fertility increases induced by maternity leave expansions from other countries of a relatively large magnitude of 1 year. The expansion that we consider was smaller, from 8 unpaid weeks to 14 mandatory paid weeks, and...
Αλέξανδρος Γ. Σφακιανάκης
1h
Sabu Thomas, Yves Grohens, Nandakumar Kalarikkal, Oluwatobi Samuel Oluwafemi, Praveen K. M. (Eds): Nanotechnology-Driven...
Sabu Thomas, Yves Grohens, Nandakumar Kalarikkal, Oluwatobi Samuel Oluwafemi, Praveen K. M. (Eds): Nanotechnology-Driven Engineered Materials—New InsightsRecent Trends in Solid-Phase Extraction for Environmental, Food and Biological Sample PreparationSomenath Mitra, Pradyot Patnaik and Barbara B. Kebbekus: Environmental Chemical Analysis, 2nd EdnCongress, Conferences, and WorkshopsAdvances in Cellulose-Based Sorbents for Extraction of Pollutants in Environmental SamplesAbstractThe effective extraction...
Αλέξανδρος Γ. Σφακιανάκης
1h
Targeted RNA-sequencing identifies FBXW4 instead of MGEA5 as fusion partner of TGFBR3 in pleomorphic...
Targeted RNA-sequencing identifies FBXW4 instead of MGEA5 as fusion partner of TGFBR3 in pleomorphic hyalinizing angiectatic tumorAbstractPleomorphic hyalinizing angiectatic tumor (PHAT) is a rare mesenchymal tumor of intermediate malignancy. PHAT, and the related hemosiderotic fibrolipomatous tumor, show a recurrent t(1;10)(p22;q24). Fluorescence in situ hybridization (FISH) and BAC (bacterial artificial chromosome) clones have previously identified TGFBR3 and MGEA5 as fusion partners. However,...
Αλέξανδρος Γ. Σφακιανάκης
1h
"Early Elective" rather than "Emergency" Laparoscopic Transcystic Exploration can prevent bile duct...
"Early Elective" rather than "Emergency" Laparoscopic Transcystic Exploration can prevent bile duct exploration/ERCP in half of patientsSclerosing Angiomatoid Nodular Transformation of the Spleen (SANT) with IgG4 Plasma Cells InfiltrationCorrection to: The Association of Body Mass Index with Postoperative Outcomes After Elective Paraesophageal Hernia RepairIn this paper, the first author's name was incorrectly tagged.Pure Laparoscopic Living Donor Right Hepatectomy Using Real-Time Indocyanine Green...
Αλέξανδρος Γ. Σφακιανάκης
1h
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
IJERPH, Vol. 16, Pages 2673: Whitefly Control Strategies against Tomato Leaf Curl New Delhi Virus...IJERPH, Vol. 16, Pages 2673: Whitefly Control Strategies against Tomato Leaf Curl New Delhi Virus in Greenhouse ZucchiniIJERPH, Vol. 16, Pages 2673: Whitefly Control Strategies against Tomato Leaf Curl New Delhi Virus in Greenhouse Zucchini International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16152673 Authors: Estefanía Rodríguez Mª Mar Téllez Dirk Janssen (1) Background:...
Αλέξανδρος Γ. Σφακιανάκης
23h
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
Morphology of the Middle Ear Ossicles in the Rodent Perimys (Neoepiblemidae) and a Comprehensive Anatomical...Morphology of the Middle Ear Ossicles in the Rodent Perimys (Neoepiblemidae) and a Comprehensive Anatomical and Morphometric Study of the Phylogenetic Transformations of these Structures in CaviomorphsAbstractThe extinct clade of caviomorph rodents Neoepiblemidae includes forms that lived in South America from the early Miocene to Pliocene. Among them is Perimys. The exceptional preservation...
Αλέξανδρος Γ. Σφακιανάκης
1d
Trauma
Tranexamic Acid Use in Open Reduction and Internal Fixation of Fractures of the Pelvis, Acetabulum, and Proximal Femur: A Randomized Controlled TrialObjective: To assess the safety and efficacy of tranexamic acid (TXA) use in fractures of the pelvic ring, acetabulum, and proximal femur. Design: Prospective, randomized controlled trial. Setting: Single Level 1 trauma center. Patients: Forty-seven patients were randomized to the study group, and 46 patients comprised the control group. Intervention:...
Αλέξανδρος Γ. Σφακιανάκης
1d
Plastic and Reconstructive Surgery
Pediatric/Craniofacial Article: Focus of Live Facebook #PRSJournalClub Q&ASurvival Following Self-inflicted Gunshots to the FaceSpecial Topic Article with an Expert DiscussionThe Use of Emotional Artificial Intelligence in Plastic SurgeryCosmetic Article Featured in the PressAppreciation of Postpartum Changes of the Rectus Muscles in Primary and Re-Do AbdominoplastyHead and Neck Article Featured in a Plastic Surgery Hot Topic VideoFacial Transplantation for an Irreparable Central and Lower Face...
Αλέξανδρος Γ. Σφακιανάκης
1d