Antibiotics, Vol. 8, Pages 88: The Case for a More Holistic Approach to Dry Eye Disease: Is It Time to Move beyond Antibiotics? Antibiotics doi: 10.3390/antibiotics8030088 Authors: Azadeh Tavakoli Judith Louise Flanagan Dry eye disease (DED) is one of the most frequent presentations to optometrists with over 16 million US adults (6.8% of adult population) diagnosed as having this disorder. The majority of associated marketed products offer relief from symptomatology but do not address...
Antibiotics, Vol. 8, Pages 87: Regulation of Geldanamycin Biosynthesis by Cluster-Situated Transcription Factors and the Master Regulator PhoP Antibiotics doi: 10.3390/antibiotics8030087 Authors: Juan F. Martín Angelina Ramos Paloma Liras Geldanamycin and the closely related herbimycins A, B, and C are benzoquinone-type ansamycins with antitumoral activity. They are produced by Streptomyces hygroscopicus var. geldanus, Streptomyces lydicus and Streptomyces autolyticus among other...
Antibiotics, Vol. 8, Pages 86: Socioeconomic Enablers for Contagion: Factors Impelling the Antimicrobial Resistance Epidemic Antibiotics doi: 10.3390/antibiotics8030086 Authors: Peter Collignon John J. Beggs Antimicrobial resistance is a growing global problem that causes increased deaths as well as increased suffering for people. Overall, there are two main factors that drive antimicrobial resistance: the volumes of antimicrobials used and the spread of resistant micro-organisms...
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