Cancers, Vol. 11, Pages 921: Comparative Transcriptomic Analysis of Temozolomide Resistant Primary GBM Stem-Like Cells and Recurrent GBM Identifies Up-Regulation of the Carbonic Anhydrase CA2 Gene as Resistance Factor Cancers doi: 10.3390/cancers11070921 Authors: Ricarda Hannen Martin Selmansberger Maria Hauswald Axel Pagenstecher Andrea Nist Thorsten Stiewe Till Acker Barbara Carl Christopher Nimsky Jörg Walter Bartsch About 95% of patients with Glioblastoma...
Sun Jun 30, 2019 03:00
Cancers, Vol. 11, Pages 920: Is the Blood an Alternative for Programmed Cell Death Ligand 1 Assessment in Non-Small Cell Lung Cancer? Cancers doi: 10.3390/cancers11070920 Authors: Emmanuel Acheampong Isaac Spencer Weitao Lin Melanie Ziman Michael Millward Elin Gray Anti-programmed cell death (PD)-1/PD-ligand 1 (L1) therapies have significantly improved the outcomes for non-small cell lung cancer (NSCLC) patients in recent years. These therapies work by reactivating the...
Sun Jun 30, 2019 03:00
Cancers, Vol. 11, Pages 919: The Antiviral Agent Cidofovir Induces DNA Damage and Mitotic Catastrophe in HPV-Positive and -Negative Head and Neck Squamous Cell Carcinomas In Vitro Cancers doi: 10.3390/cancers11070919 Authors: Femke Verhees Dion Legemaate Imke Demers Robin Jacobs Wisse Evert Haakma Mat Rousch Bernd Kremer Ernst Jan Speel Cidofovir (CDV) is an antiviral agent with antiproliferative properties. The aim of our study was to investigate the efficacy of...
Sun Jun 30, 2019 03:00
Cancers, Vol. 11, Pages 917: DNA-Repair Gene Mutations Are Highly Prevalent in Circulating Tumour DNA from Multiple Myeloma Patients Cancers doi: 10.3390/cancers11070917 Authors: Sridurga Mithraprabhu Jay Hocking Malarmathy Ramachandran Kawa Choi Daniela Klarica Tiffany Khong John Reynolds Andrew Spencer Mutational characterisation utilising plasma (PL)-derived circulating tumour DNA (ctDNA) in multiple myeloma (MM) has been recently described. Mutational analyses...
Sat Jun 29, 2019 03:00
Cancers, Vol. 11, Pages 918: Inhibition of protein phosphatase 1 stimulates noncanonical ER stress eIF2α activation to enhance fisetin-induced chemosensitivity in HDAC inhibitor-resistant hepatocellular carcinoma cells Cancers doi: 10.3390/cancers11070918 Authors: Liu Yu-Chun Chang Kuo Chen Hsu Tu Yeh Viswanadha Liao Huang Hepatocellular carcinoma (HCC) is a common fatal type of malignant tumor that has highly metastatic and recurrent properties....
Sat Jun 29, 2019 03:00
Cancers, Vol. 11, Pages 916: Exploiting Mitochondrial Vulnerabilities to Trigger Apoptosis Selectively in Cancer Cells Cancers doi: 10.3390/cancers11070916 Authors: Christopher Nguyen Siyaram Pandey The transformation of normal cells to the cancerous stage involves multiple genetic changes or mutations leading to hyperproliferation, resistance to apoptosis, and evasion of the host immune system. However, to accomplish hyperproliferation, cancer cells undergo profound metabolic reprogramming...
Sat Jun 29, 2019 03:00
Cancers, Vol. 11, Pages 914: Urinary Metabolic Signatures Detect Recurrences in Non-Muscle Invasive Bladder Cancer Cancers doi: 10.3390/cancers11070914 Authors: Alba Loras M. Carmen Martínez-Bisbal Guillermo Quintás Salvador Gil Ramón Martínez-Máñez José Luis Ruiz-Cerdá Patients with non-muscle invasive bladder cancer (NMIBC) undergo lifelong monitoring based on repeated cystoscopy and urinary cytology due to the high recurrence rate of this tumor. Nevertheless, these...
Sat Jun 29, 2019 03:00
Cancers, Vol. 11, Pages 915: Targeting the Immune Microenvironment in Lymphomas of B-Cell Origin: From Biology to Clinical Application Cancers doi: 10.3390/cancers11070915 Authors: Mulder Wahlin Österborg Palma In lymphomas of B-cell origin, cancer cells orchestrate an inflammatory microenvironment of immune and stromal cells that sustain the tumor cell survival and growth, known as a tumor microenvironment (TME). The features of the TME differ between the different lymphoma...
Sat Jun 29, 2019 03:00
Cancers, Vol. 11, Pages 913: Differentiation Induction as a Response to Irradiation in Neural Stem Cells In Vitro Cancers doi: 10.3390/cancers11070913 Authors: Jana Konířová Lukáš Cupal Šárka Jarošová Anna Michaelidesová Jana Vachelová Marie Davídková Petr Bartůněk Martina Zíková Radiotherapy plays a significant role in brain cancer treatment; however, the use of this therapy is often accompanied by neurocognitive decline that is, at least partially, a consequence...
Sat Jun 29, 2019 03:00
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