Cells, Vol. 8, Pages 659: Inflammatory Bowel Disease: A Stressed “Gut/Feeling” Cells doi: 10.3390/cells8070659 Authors: Yvonne Oligschlaeger Tulasi Yadati Tom Houben Claudia Maria Condello Oliván Ronit Shiri-Sverdlov Inflammatory bowel disease (IBD) is a chronic and relapsing intestinal inflammatory condition, hallmarked by a disturbance in the bidirectional interaction between gut and brain. In general, the gut/brain axis involves direct and/or indirect communication via...
Sun Jun 30, 2019 03:00
Cells, Vol. 8, Pages 655: Synthesis and Evaluation of Novel Pyrazole Ethandiamide Compounds as Inhibitors of Human THP-1 Monocytic Cell Neurotoxicity Cells doi: 10.3390/cells8070655 Authors: Jordan A. McKenzie Reham F. Barghash Azhaar T. Alsaggaf Omkar Kulkarni Kalun Boudreau Frederic Menard Edward G. Neeland Andis Klegeris Neuroinflammation and microglia-mediated neurotoxicity contribute to the pathogenesis of a broad range of neurodegenerative diseases; therefore,...
Sat Jun 29, 2019 03:00
Cells, Vol. 8, Pages 657: Post-Translational Modifications of Proteins: Novel Insights in the Autoimmune Response in Rheumatoid Arthritis Cells doi: 10.3390/cells8070657 Authors: Francesco Carubbi Alessia Alunno Roberto Gerli Roberto Giacomelli Post-translational modifications (PTM) are chemical changes mostly catalyzed by enzymes that recognize specific target sequences in specific proteins. These modifications play a key role in regulating the folding of proteins, their targeting...
Sat Jun 29, 2019 03:00
Cells, Vol. 8, Pages 656: The Inhibition on MDFIC and PI3K/AKT Pathway Caused by miR-146b-3p Triggers Suppression of Myoblast Proliferation and Differentiation and Promotion of Apoptosis Cells doi: 10.3390/cells8070656 Authors: Weiling Huang Lijin Guo Minxing Zhao Dexiang Zhang Haiping Xu Qinghua Nie Accumulating studies report that microRNAs (miRNAs) are actively involved in skeletal myogenesis. Previously, our study revealed that miR-146b-3p was related to the growth...
Sat Jun 29, 2019 03:00
Cells, Vol. 8, Pages 654: Viroporins in the Influenza Virus Cells doi: 10.3390/cells8070654 Authors: Janet To Jaume Torres Influenza is a highly contagious virus that causes seasonal epidemics and unpredictable pandemics. Four influenza virus types have been identified to date: A, B, C, and D, where only A–C are known to infect humans. Influenza A (IAV) and B (IBV) viruses are responsible for seasonal influenza epidemics in humans and are responsible for up to a billion...
Sat Jun 29, 2019 03:00
Cells, Vol. 8, Pages 653: The Aberrant Expression of the Mesenchymal Variant of FGFR2 in the Epithelial Context Inhibits Autophagy Cells doi: 10.3390/cells8070653 Authors: Nanni Ranieri Persechino Torrisi Belleudi Signaling of the epithelial splice variant of fibroblast growth factor receptor 2 (FGFR2b) triggers both differentiation and autophagy, while the aberrant expression of the mesenchymal FGFR2c isoform in epithelial cells induces impaired differentiation, epithelial...
Sat Jun 29, 2019 03:00
Cells, Vol. 8, Pages 652: Prognostic Significance of TWIST1, CD24, CD44, and ALDH1 Transcript Quantification in EpCAM-Positive Circulating Tumor Cells from Early Stage Breast Cancer Patients Cells doi: 10.3390/cells8070652 Authors: Areti Strati Michail Nikolaou Vassilis Georgoulias Evi S. Lianidou (1) Background: The aim of the study was to evaluate the prognostic significance of EMT-associated (TWIST1) and stem-cell (SC) transcript (CD24, CD44, ALDH1) quantification in EpCAM+...
Sat Jun 29, 2019 03:00
Cells, Vol. 8, Pages 658: The Lymphatic Headmaster of the Mast Cell-Related Splanchnic Inflammation in Portal Hypertension Cells doi: 10.3390/cells8070658 Authors: Aller M.A. Blanco-Rivero J. Arias N. Santamaria L. Arias J. Portal hypertension is a common complication of liver disease, either acute or chronic. Consequently, in chronic liver disease, such as the hypertensive mesenteric venous pathology, the coexisting inflammatory response is classically characterized by the...
Sat Jun 29, 2019 03:00
Cells, Vol. 8, Pages 651: CCR5 Promoter Polymorphism −2459G > A: Forgotten or Ignored? Cells doi: 10.3390/cells8070651 Authors: Mehlotra C-C chemokine receptor 5 (CCR5) polymorphisms, particularly a 32-base pair deletion (∆32) in the open reading frame and −2459G > A in the promoter, are well known for their associations with HIV-1 infection and/or disease progression in a variety of studies. In this era of an HIV cure, where all the emphasis is on ∆32, it seems...
Fri Jun 28, 2019 03:00
Cells, Vol. 8, Pages 650: Ddx4+ Oogonial Stem Cells in Postmenopausal Women’s Ovaries: A Controversial, Undefined Role Cells doi: 10.3390/cells8070650 Authors: Silvestris Cafforio Felici Cormio D’Oronzo Recent studies support the existence of oogonial stem cells (OSCs) in the ovarian cortex of different mammals, including women.These cells are characterized by small size, membrane expression of DEAD(Asp-Glu-Ala-Asp)-box polypeptide-4 (Ddx4), and stemness properties (such...
Fri Jun 28, 2019 03:00
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