ORODISPERSIBLE TABLETS: A PROFICIENT DRUG DELIVERANCE TOOL FOR ALL AGE’S PATIENTS

2016-10-16T02-20-53Z
Source: Indo American Journal of Pharmaceutical Research
Ajay Aseri*,, Pradeep Kumar,, Sandeep Bhatia,, Shiv Garg.
Oral route is most expedient, financially viable, secure route of drug administration with excellent patient compliance. Orodispersible drug delivery Systems was an progression that gain limelight in early 1970s and rule over the use of long-established oral dosage forms such as conventional tablets, syrups, capsules. These Orodispersible tablets (ODTs) are new-fangled tablets have acceptance by geriatric, bedridden , young patients particularly suffering with dysphagia, tremors problems, unconscious and paediatric patients at higher extent now days. It gets readily dissolve or disintegrate in the saliva less than a minute and no necessitate of water to swallow. This review contribute various Desired characteristics, advantages, limitations, Biopharmaceutical consideration/ Biotransformation, Release mechanism of drug, Patients counselling, drug candidates for ODTs, formulation aspects; Fillers, Super-disintegrate (Synthetic /Natural) employed, Co-processed excipients, Taste camouflaging agents/taste modifiers, Patented technologies developed for ODTs, Commercially authorized ODTs Holders.


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