DRUG USE EVALUATION OF ANTIHYPERTENSIVE DRUGS IN THE TERTIARY CARE HOSPITAL

2016-10-16T02-20-53Z
Source: Indo American Journal of Pharmaceutical Research
Kamal Pandey, Prithvi Bikram Thakur, K. RamKumar, Dr. Praveen Kumar, Dr. B.A Vishwanath.
AIM: To assess the Drug use evaluation of antihypertensive drugs in Tertiary Care Hospital. MATERIALS AND METHODS: Drug use utilization data of 200 Patients, attending inpatient department of Aster CMI Hospital for 6 month was collected from Patients Case Notes and prescriptions. This study is retrospective study. The data were analyzed to find out the demographic characteristics of the patient, number of drugs prescribed per patients, drugs which are commonly prescribed, mono therapy, combination therapy (two drug therapy, three drug therapies), route of drug administration, adherence with JNC VIII, drug treatment based on stages of hypertension, co-morbidities of patients. Patients suffering from hypertension with or without co-morbid conditions were included in the study. RESULTS: During the 6 months period of study 200 prescriptions for Hypertension were analyzed. Among 200 prescriptions most of the patients were Male (57%) while 43% were female and major age group having HTN was found to be 60-70 years (32%). Regarding co-morbidity 33.5% patients had HTN with DM. The study revealed that most of the patients were on combination of antihypertensive drugs (59%) while 41% patients received monotherapy. Mostly prescribed route of administration was oral route (96%). Among 200 prescription 24% prescriptions had drug interactions. Among 200 prescriptions 75% of prescriptions were found to be adhered with JNC VIII guidelines. CONCLUSION: 25% deviation from JNC VIII guidelines and 24% prescription had drug interaction was observed in the treatment with respect to selection of antihypertensive drugs.


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