CYTOTOXIC AND ANTIPROLIFERATIVE ACTIVITY OF MEDICINAL PLANTS IN CANCER CELLS

2016-10-16T06-25-49Z
Source: Indo American Journal of Pharmaceutical Research
Mangala S.N, Ganga Vani. V, Keerthi.N.L, Dr. K.N. Geetha, Dr.Senthil Duraiswamy.
The present study is aimed to investigate the cytoxicity and antiproliferative activities of the 6 Indian medicinal plants namely Pavonia odorata, Gardenia latifolia, Canthium dicoccum, Limonia monophylla, Bridelia roxburghiana and Wrightia tinctoria. The above plants were extracted with methanol using a soxhlet apparatus. These various extracts were evaluated in vitro using cancer cell lines like HL-60, Calu-6 and Colo-205. MTT, wound healing and cell cycle analysis in vitro assays were performed. The results revealed that the plants Pavonia odorata and Wrightia tinctoria possessed cytotoxic activity and antiproliferating activity.


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