MUNIX in the clinic in ALS: MUNE comes of age

Motor unit counting in individual muscles – motor unit number estimation (MUNE) – is a well-established technique that has never quite become established in clinical practice, despite its obvious potential utility in assessing the motor innervation of a muscle. Although such a direct count should be intuitively better than assessing motor unit waveforms – it has remained a not quite achievable holy grail of EMG, especially in the assessment of ALS, a disorder in which a reliable MUNE test should have a major role.

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