Genome organization: In the beginning there was order

Nature Reviews Genetics 18, 327 (2017). doi:10.1038/nrg.2017.37

Author: Carolina Perdigoto

During the early stages of embryonic development, the zygotic genome acquires a unique chromatin configuration that ensures the adequate expression of the embryonic developmental programme. How and when the zygotic genome adopts its singular chromatin architecture is the focus of two studies published in Nature

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