Nature Reviews Genetics 18, 331 (2017). doi:10.1038/nrg.2016.160
Authors: Amit V. Khera & Sekar Kathiresan
Coronary artery disease is the leading global cause of mortality. Long recognized to be heritable, recent advances have started to unravel the genetic architecture of the disease. Common variant association studies have linked approximately 60 genetic loci to coronary risk. Large-scale gene sequencing efforts and
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