2-1-05. PR interval of electrocardiography is significantly correlated with the findings of cardiac MIBG scintigraphy in Parkinson’s disease

Cardiac 123I-metaiodobenzylguanidine scintigraphy (MIBG) has been used to assess the postganglionic presynaptic cardiac sympathetic nerve endings and demonstrated an uptake reduction in patients with Parkinson's disease (PD). On the other hand, epidemiologic research showed that electrocardiography (ECG) abnormalities occurred prior to motor signs in PD. In this study, we investigated whether the electrical conduction system of the heart was impaired in PD. Clinical features, ECG and MIBG parameters were analyzed in 191 patients with PD, 42 with multiple system atrophy (MSA) and 124 normal controls (NL).

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