Objectives. To evaluate the effects of treating mothers with multiple sclerosis disease-modifying drugs (MS DMD) on the physical and mental development of children in the first year of life. Materials and methods. A total of 30 cases of pregnancy ending with live births in patients conceiving after confirmed diagnosis of MS were studied. Mothers not receiving MS DMD at the moment of conception (controls) were treated with interferon-β (IFN) (13 cases) or glatiramer acetate (GA) (10 cases) at conception. Patients were investigated using structured interviews, examination of children with assessment of standard anthropometric indicators and the motor and neuropsychological development scale (WHO Six Milestones), examination of medical records, and statistical analysis. Results and conclusions. The study confirmed data on the negative effects of MS on the growth and development of fetuses and the positive effects of MS DMD treatment in mothers at different periods on anthropometric indicators and child development during the first year of life. These results lead to the conclusion that MS DMD have positive effects not only on the course of illness and the patient herself, but also potentially improve prognoses for future offspring.
from Physiology via xlomafota13 on Inoreader https://ift.tt/2OC7VFi
via IFTTT
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου
Σημείωση: Μόνο ένα μέλος αυτού του ιστολογίου μπορεί να αναρτήσει σχόλιο.