Decreased alpha2 connectivity in EEG is correlated with the cognitive and psychiatric manifestations of Parkinson’s disease

Parkinson's disease (PD) was traditionally thought of as a motor disorder induced by selective apoptosis of unknown cause affecting dopaminergic neurons in the pars compacta of the substantia nigra (SNpc), leading, in turn, to basal ganglionic dysfunction that manifests itself as bradykinesia, rigidity, and rest tremor. These features remain important elements of the current diagnostic criteria for PD, which, however, also give a prominent role to non-motor manifestations of the disease (Postuma et al.

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