Pain-motor Integration and Chronic Pain: One Step Ahead

Pain-motor integration refers to physiological processes responsible for mutual interaction between nociceptive and motor information in the central nervous system. Two separate lines of evidence support the hypothesis that pain-motor integration mechanisms operate in the human cerebral cortex. First, epidural motor cortex stimulation (MCS), as well as non-invasive brain stimulation (NIBS) protocols delivered over the primary motor cortex (M1), can both improve pain in patients with drug-resistant chronic pain.

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