Τρίτη 12 Δεκεμβρίου 2017

High-resolution mapping of cis-regulatory variation in budding yeast [Genetics]

Genetic variants affecting gene-expression levels are a major source of phenotypic variation. The approximate locations of these variants can be mapped as expression quantitative trait loci (eQTLs); however, a major limitation of eQTLs is their low resolution, which precludes investigation of the causal variants and their molecular mechanisms. Here we...

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