P 155 First evidence for glial pathology in late life minor depression – S100B is increased in males with minor depression – results form LIFW-adult study

Minor depression is as ubthreshold depressive disorder. It is diagnosed when a patient suffers from 2 to 4 depressive symptoms for at least 2weeks. Though minor depression affects nearly ten percent of the elderly population, its pathophysiology has hardly been investigated. In our study we assessed serum levels of biomarkers for plasticity, glial and neuronal function: brain-derived neurotrophic factor (BDNF), S100B and neuron specific enolase (NSE).

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