Τρίτη 29 Αυγούστου 2017

In vivo loss-of-function screens identify KPNB1 as a new druggable oncogene in epithelial ovarian cancer [Genetics]

Epithelial ovarian cancer (EOC) is a deadly cancer, and its prognosis has not been changed significantly during several decades. To seek new therapeutic targets for EOC, we performed an in vivo dropout screen in human tumor xenografts using a pooled shRNA library targeting thousands of druggable genes. Then, in follow-up...

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