Τρίτη 29 Αυγούστου 2017

Feedback amplification loop drives malignant growth in epithelial tissues [Genetics]

Interactions between cells bearing oncogenic mutations and the surrounding microenvironment, and cooperation between clonally distinct cell populations, can contribute to the growth and malignancy of epithelial tumors. The genetic techniques available in Drosophila have contributed to identify important roles of the TNF-α ligand Eiger and mitogenic molecules in mediating these...

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