Πέμπτη 20 Ιουλίου 2017

Risk of depression enhances auditory pitch discrimination in the brain as indexed by the Mismatch Negativity

S13882457.gif

Publication date: Available online 18 July 2017
Source:Clinical Neurophysiology
Author(s): L. Bonetti, N.T. Haumann, P. Vuust, M. Kliuchko, E. Brattico
ObjectiveDepression is a state of aversion to activity and low mood that affects behaviour, thoughts, feelings and sense of well-being. Moreover, the individual depression trait is associated with altered auditory cortex activation and appraisal of the affective content of sounds.MethodsMismatch negativity responses (MMNs) to acoustic feature changes (pitch, timbre, location, intensity, slide and rhythm) inserted in a musical sequence played in major or minor mode were recorded using magnetoencephalography (MEG) in 88 subclinical participants with depression risk.ResultsWe found correlations between MMNs to slide and pitch and the level of depression risk reported by participants, indicating that higher MMNs correspond to higher risk of depression. Furthermore we found significantly higher MMN amplitudes to mistuned pitches within a major context compared to MMNs to pitch changes in a minor context.ConclusionsThe brains of individuals with depression risk are more responsive to mistuned and fast pitch stimulus changes, even at a pre-attentive level.SignificanceConsidering the altered appraisal of affective contents of sounds in depression and the relevance of spectral pitch features for those contents in music and speech, we propose that individuals with subclinical depression risk are more tuned to tracking sudden pitch changes.



from Physiology via xlomafota13 on Inoreader http://ift.tt/2ueEYEh
via IFTTT

Δεν υπάρχουν σχόλια:

Δημοσίευση σχολίου

Σημείωση: Μόνο ένα μέλος αυτού του ιστολογίου μπορεί να αναρτήσει σχόλιο.