Τρίτη 13 Δεκεμβρίου 2016

From profiles to function in epigenomics

Nature Reviews Genetics 18, 51 (2017). doi:10.1038/nrg.2016.138

Authors: Stefan H. Stricker, Anna Köferle & Stephan Beck

Myriads of epigenomic features have been comprehensively profiled in health and disease across cell types, tissues and individuals. Although current epigenomic approaches can infer function for chromatin marks through correlation, it remains challenging to establish which marks actually have causative roles in gene regulation and



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