Τρίτη 13 Δεκεμβρίου 2016

Epigenomics: Deciphering non-coding variation with 3D epigenomics

Nature Reviews Genetics 18, 4 (2017). doi:10.1038/nrg.2016.161

Author: Darren J. Burgess

The majority of disease-associated genetic variants identified by genome-wide association studies (GWAS) are in non-coding regions of the genome. This indicates a pathological regulatory role for these variants, but identifying mechanisms of action and their corresponding target genes is often challenging. As part of the



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