ANTIBACTERIAL, ANTIFUNGAL AND CYTOTOXICITY ACTIVITY OF METHANOLIC EXTRACT OF EUPHORBIA HITRA AGAINST PC-3 AND MCF-7 CELL LINES

2016-11-08T01-11-23Z
Source: Indo American Journal of Pharmaceutical Research
Perumal .R, Selvamaleeswaran .P, Maheswaran .S, Sureshkumar .M.
Plants are considered to be a perennial source of medicine from time immemovial. The phytochemical screening was carried on the leaves extracts of Euphorbia hitra, divulged the presence of some active ingredients namely alkaloids, tannins, saponnins, phenols, steroids, flavanoids and terpenoids. The antibacterial activities of methanol extract of Euphorbia hitra aganist some pathogens; Proteus vulgaris Enterococcus faecalis and Pseudomonas aeruginosa .The well diffusion method was used to determine the antibacterial activity. The antifungal activities of methanol extract of Euphorbia hitra aganist some fungus; Trichophyton rubrum, Trichophyton mentagarophytes and Alternaria solan the disc diffusion method was used to regulate the antifungal activity. The prostate cancer is the most important form of cancer in males and the second leading cause of cancer related death.MCF-7 and PC-3 cell lines was derived from adinocarcinoma of human prostate this was assayed for MTT assay on treatment with Methanolic leaf extract of Euphorbia hitra where in inhibition of the cell growth was noticed.


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