Dietary glycemic index and glycemic load in children with phenylketonuria: A case–control study

The restriction of dietary phenylalanine (phe) remains the main treatment for Phenylketonuria (PKU). The primary aim of this study was to examine dietary daily glycemic index (GI) and glycemic load (GL) in PKU children on phe-free diet. Twenty-one PKU and 21 healthy children [mean (SD) 8.0 (2.2) years], age and sex matched were enrolled. In all children daily energy (Kcal/die), macronutrient (% of daily energy), fiber (g/die) intakes, GI and GL were determined by 3-days food record. No significant difference was observed for daily energy intake between PKU and healthy children (p=0.570).

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