DEFICIENCY OF VITAMIN D AND ITS RELATIONSHIP WITH HYPOTHYROIDISM

2016-05-04T19-37-24Z
Source: Indo American Journal of Pharmaceutical Research
Pallavi Mahajan, Amarjeet S Bhatia.
The prevalence of vitamin D deficiency is 70%100% in the general population. It exists in epidemic proportions all over the Indian subcontinent. Calcidiol is considered as the real indicator of the total vitamin D stores and is being currently used for clinical evaluation of the vitamin D. Vitamin D is recognized to be an essential element for bone metabolism and skeletal health. Its deficiency can cause rickets in children and osteoporosis in adults. It has been identified as a risk factor for cancers, multiple sclerosis, atherosclerosis, infectious diseases and other autoimmune diseases. Vitamin D also play a role in the pathogenesis of several endocrine diseases, like autoimmune thyroid diseases, primary hyperparathyroidism, adrenal diseases, type 1 diabetes (T1DM), type 2 diabetes (T2DM), and polycystic ovary syndrome (PCOS). The present study was conducted with the aim to estimate and compare the levels of vitamin D in normal healthy adults and patients with hypothyroidism diagnosed on the basis of raised thyroid stimulating hormone levels. The mean ± standard deviation value of vitamin D was 20.53±14.42 ng/ml in patients with hypothyroidism whereas in normal healthy adults, the mean ± standard deviation value of vitamin D was 26.88±16.11 ng/ml. The decreased level of vitamin D was found in patients with hypothyroidism. Hence, further research should be done to find the relationship of vitamin D with thyroid antibodies.


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