Quantitative analysis of surface electromyography: biomarkers for convulsive seizures

In spite of the advances in functional neuroimaging methods, we still know little about the pathomechanisms of the convulsive epileptic seizures in humans, and most of the evidence comes from animal models (Fusco et al., 2008; Zifkin and Dravet, 2008). Limited investigation time makes it unlikely that such an event is recorded in the scanner, and artefacts caused by excessive motor activity make it technically extremely challenging (Moeller et al., 2009). EEG and MEG signals are typically distorted by signals from the head muscle, and also by electrode artefacts.

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