- 18 items
- 18-72 (higher scores reflect more apathy)
- Items are scored on 4-point Likert scale with descriptors for the "self" version (not at all true, slightly true, somewhat true, very true) and those for the clinician and informant version (not at all characteristic, slightly characteristic, somewhat characteristic, very characteristic)
- Some items must be reverse scored because of the way they are written
- Two open questions are also asked (number of items reported, details offered in response to questions) to characterize apathy
- Administration instructions are provided in the Marin et al 1991 reference; pages 161-162.
- Alzheimer's Disease
- Depression
- Older adults
- Stroke
- Hypoxic brain damage
- Traumatic brain injury
- Parkinson's Disease
- Schizophrenia
Young adult controls: (Kant et al, 1998; n=108, age range 20-65 years, 94.5% in 20-49 age range, 49% male) Mean AES-S was 24.4 (4.5), therefore cutoff score of >34 indicating apathy (2 SD above mean)
Acquired brain injury: (Andersson et al, 1999a; n=72; mean age = 30.1 (ages 16-60 years old); mean time post injury = 12.6 months ; TBI, CVA and hypoxic brain damage)
- Score greater than 34 indicates apathy on AES-C
Traumatic brain injury: Andersson et al, 1999b (n=30; mean age = 30.1( ages 16-64); mean time post injury = 10.5 months; inpatient TBI)
- Score greater than 34 indicates apathy on AES-C
Glenn et al, 2002 (n=46; mean age 43.1(14.9) years; mean time since injury 43.0 months; initial injury severity 52% mild, 18% moderate, 30% severe)
- Investigators were not able to identify a reasonable cut-off score of AES-I (area under ROC curve was 0.62) or AES-S (area under ROC curve was 0.74). AES-C score of >32 had the best combination of sensitivity and specificity (area under ROC curve 0.82), with sensitivity of 95% but specificity of 0% to predict an ordinal rating of presence of behaviors that reflect apathy (a 7 point scale developed for the study).
(Lane-Brown & Tate, 2009; n=34, mean age=34.4(9.4); mean time post injury= 80.6 months; mean duration of PTA 53.2 (33.5) days)
- Adequate diagnostic accuracy, with score greater than 36.5 resulted in ROC of .8, with sensitivity of 83% and specificity of 67%. A higher cutpoint could be used to increase specificity if desired (see Lane-Brown for values). It is likely that there is some overlap of symptoms related to fatigue and/or depression in this population that should be considered for clinical management.
Young adult controls: (Kant et al, 1998)
- Mean AES-S = 24.4 (4.5)
Traumatic brain injury: (Glenn et al, 2002)
- Mean AES-S scores = 37 (8.6), no difference between levels of injury severity
(Kant et al, 1998; n=83; mean age 38 (12.3) years; TBI referrals to neuropsychiatric outpatient clinic)
- Mean AES-scores = 40.5 (6.3), 71% met criteria for apathy
Mixed sample: (Marin 1991; n=123; aged 53-85, mixed sample of stroke, AD, depression, community dwelling well older adults)
- Excellent test-retest reliability (Pearson= .88 (AES-C); Pearson = .94 (AES-I); Pearson= .76 (AES-S))
Mixed sample: (Marin et al, 1991)
- Excellent interrater reliability (ICC= .94)
Acquired brain injury: (Andersson, 1999a)
- Excellent internal consistency (Chronbach's alpha of AES-C=.84)
TBI: (Andersson 1999b)
- Excellent internal consistency(Chronbach's alpha of AES-C=.89)
(Andersson & Bergedalen, 2002; n= 53; mean age = 28.3 years (2.38); mean time post injury= 12.2 months (10.6))
- Excellent internal consistency (Chronbach's alpha of AES-C=.87)
(Lane-Brown, 2009)
- Excellent internal consistency (Chronbach's alpha of AES-I= .89)
Predictive validity:
Mixed sample: (Marin et al, 1991)
- AES-C predicts average scores and time spontaneously engaged on videogame at levels of significance p<.002)
Mixed sample: (Marin et al, 1991)
- Excellent convergent validity of AES-C with other forms (r= .62-.72); Adequate discriminant validity differentiating apathy from depression and anxiety (r=.35-.39); Excellent differentiation between patients with Alzheimer's disease, right and left hemisphere stroke and major depression (F=18.86, p<.001)
Acquired BI: (Andersson et al, 1999a)
- AES-C correlates as expected with items on depression scale (excellent levels with positive items, insignificant correlation with items reflecting depression).
- Differentiates between hypoxia and other forms of acquired brain injury.
TBI: (Andersson et al, 1999b)
- Significant relationships between AES-C and heart rate/blood pressure reactivity and mean arterial pressure (beta values reported, p<.01). Significant inverse relationships between AES-C and emotional discomfort.
(Andersson and Bergedalen, 2002)
- Adequate negative correlation between AES-C and acquistion/memory (r=-.50).
(Lane-Brown, 2009)
- Excellent correlation with the Frontal Systems Behavior Scale-Apathy items (r=.71)
Translated AES:
Spanish (slide 62-63):
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Andersson, A. F. S. (2000). "Coping strategies in patients with acquired brain injury: relationships between coping, apathy, depression and lesion location." Brain Injury 14(10): 887-905.
Andersson, S. and Bergedalen, A. M. (2002). "Cognitive correlates of apathy in traumatic brain injury." Neuropsychiatry, Neuropsychology, and Behavioral Neurology 15(3): 184-191. Find it on PubMed
Andersson, S., Gundersen, P. M., et al. (1999). "Emotional activation during therapeutic interaction in traumatic brain injury: effect of apathy, self-awareness and implications for rehabilitation." Brain Injury 13(6): 393-404. Find it on PubMed
Andersson, S., Krogstad, J. M., et al. (1999). "Apathy and depressed mood in acquired brain damage: relationship to lesion localization and psychophysiological reactivity." Psychological Medicine 29(2): 447-456. Find it on PubMed
Clarke, D. E., Van Reekum, R., et al. (2007). "An appraisal of the psychometric properties of the Clinician version of the Apathy Evaluation Scale (AES-C)." Int J Methods Psychiatr Res 16(2): 97-110. Find it on PubMed
Glenn, M. (2005). "The Apathy Evaluation Scale." The Center for Outcome Measurement In Brain Injury.
Glenn, M. B., Burke, D. T., et al. (2002). "Cutoff score on the apathy evaluation scale in subjects with traumatic brain injury." Brain Injury 16(6): 509-516. Find it on PubMed
Kant, R., Duffy, J. D., et al. (1998). "Prevalence of apathy following head injury." Brain Injury 12(1): 87-92. Find it on PubMed
Lane-Brown, A. T. and Tate, R. L. (2009). "Measuring apathy after traumatic brain injury: Psychometric properties of the Apathy Evaluation Scale and the Frontal Systems Behavior Scale." Brain Injury 23(13-14): 999-1007. Find it on PubMed
Marin, R. S., Biedrzycki, R. C., et al. (1991). "Reliability and validity of the Apathy Evaluation Scale." Psychiatry Research 38(2): 143-162. Find it on PubMed
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