Τετάρτη 16 Μαρτίου 2016

Gene regulation: A gene-centric analysis of transcriptional cascades

Nature Reviews Genetics 17, 193 (2016). doi:10.1038/nrg.2016.30

Author: Ross Cloney

The past 15 years have seen the gene-specific approach to studying the regulation of gene expression joined by global-scale analysis, enabled by microarrays, whole-genome sequencing and RNA sequencing (RNA-seq). The Toll-like receptor 4 (TLR4)-mediated cascade of transcriptional activity, which is induced by lipopolysaccharide (LPS) or



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