Nature Reviews Genetics 17, 207 (2016). doi:10.1038/nrg.2016.4
Authors: Wenbo Li, Dimple Notani & Michael G. Rosenfeld
Networks of regulatory enhancers dictate distinct cell identities and cellular responses to diverse signals by instructing precise spatiotemporal patterns of gene expression. However, 35 years after their discovery, enhancer functions and mechanisms remain incompletely understood. Intriguingly, recent evidence suggests that many, if not all, functional
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