Psychophysical investigations were carried out on patients with depressive and anxious-depressive disorders, including ECG, EEG, speech signal recordings, and testing of visuomotor reactions. Patients showed deterioration in measures of variational cardiometry relative to healthy subjects regardless of the presence or absence of anxiety syndrome. EEG dynamics during cognitive tests and the variability of the correlation dimension of the speech signal changed specifically in patients with anxiety syndrome. Increases in the standard deviation of the correlation dimension of the speech signal may provide an indicator of the presence of a depressive disorder, changes in the speech signal depending on the type of depressive disorder.
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