Pediatric chronic inflammatory bowel disease in a German statutory health INSURANCE - incidence rates from 2009 - 2012

Objective: The incidence of pediatric inflammatory bowel disease (PIBD) varies over time and geographic region. We attempted to generate incidence rates form German health insurance data. Methods: We used health care data for 2009–2015 provided by BARMER, a major statutory health insurance company in Germany, insuring approx. 8% of the pediatric population. We applied a Canadian case definition for PIBD based on ICD coding, documentation of (ileo)colonoscopy and the number of PIBD related visits, without external validation for Germany. An internal validation of the specificity of the diagnosis by checking whether the identified incident cases had also prescriptions of PIPD specific drugs was performed. Results: In 2012, 187 pediatric patients were newly diagnosed, accounting for an overall PIBD incidence of 17.41 (95%-CI: 15.08-20.10) per 100,000 insured children and adolescents from 0-17.9 years per year compared to 13.65/100,000 (95%-CI: 11.63-16.01) in 2009. The age specific incidence showed a steep increase as of the age of 7 years. The PIBD prevalence in 2012 was 66.29/100,000. Conclusion: In conclusion, the incidence of PIBD in 0 -17.9-year olds in Germany with health BARMER health insurance in 2012 is among the highest reported in the literature. Address correspondence and reprint requests to Dr. Lucia Albers, LMU, Institute of Social Pediatrics and Adolescents Medicine, Haydnstraße 5, 80336 Munich (e-mail: lucia.albers@med.uni-muenchen.de). Received 27 March, 2018 Accepted 20 September, 2018 Regina Wittig and Lucia Albers contributed equally. This publication is part of the doctoral thesis of Regina Wittig. Source of Funding: There was no funding for this study. Conflicts of Interest: The authors declare none conflict of interest. Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Website (www.jpgn.org). © 2018 by European Society for Pediatric Gastroenterology, Hepatology, and Nutrition and North American Society for Pediatric Gastroenterology,

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