Delirium is not associated with altered hub flexibility of the posterior cingulate cortex

Delirium is an acute disturbance of attention, awareness and cognition that tends to fluctuate over time. It is an acute and serious condition, affecting more than 15% of all hospitalized patients, and is related to poor outcomes such as prolonged length of hospital stay and long-term cognitive impairment. Although previous studies suggest multiple hypotheses towards underlying mechanisms, e.g. neurotransmitter imbalances, abnormal stress response and neuroinflammation, the exact pathogenesis of delirium remains poorly understood.

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