Ultrasound-guided, open-source microneurography: Approaches to improve recordings from peripheral nerves in man

Microneurography is an established technique that allows recordings to be made from peripheral nerves in humans (Vallbo and Hagbarth, 1968, Vallbo et al. , 2004). This includes the ability to record from afferent neurones conducting in the C-fibre range (Torebjork and Hallin, 1974), which are predominantly nociceptors. In the pain field, the normal response characteristics of several classes of nociceptors have been defined and a growing body of work is now identifying pathophysiological changes in human disease (Donadio and Liguori, 2015).

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