Elevated inflammatory cytokine expression in CSF from patients with symptomatic thoracic disc herniations correlates with increased pain scores

The pathophysiology of pain in symptomatic thoracic disc herniation (TDH) patients remains poorly understood. Mere mechanical compression of the spinal cord and/or the exiting nerve root by a prolapsed disc cannot explain the pathogenesis of pain in all cases. Previous studies report a direct correlation between the levels of proinflammatory cytokines in disc biopsies and the severity of leg pain in patients with lumbar disc herniations. A similar correlation in patients with TDHs has not been investigated.

from Sports Medicine via xlomafota13 on Inoreader https://ift.tt/2n36ZdA
via IFTTT