Three- dimensional microstructural reconstruction of the ovine intervertebral disc using ultra-high field MRI

The intervertebral disc (IVD) is a complex organ which acts as a flexible coupling between two adjacent vertebral bodies and must therefore accommodate compression, bending and torsion. It consists of three main components which are elegantly structured to allow this: the annulus fibrosus (AF), the nucleus pulposus (NP) and the end-plates (EP).

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