5. Prospective pre-emptive EEG study prior to west syndrome

Since the original description of hypsarrhythmia by visual inspection as a "chaotic" and disorganized pattern in 1954, we have continued this clinical practice of EEG interpretation with solely visual inspection until the present day. The description of hypsarrhythmia as "chaotic" [Gibbs EL, Fleming MM, Gibbs FA. Pediatrics 1954;13(1):66–73], was challenged by van Putten and Stam 17 years ago [IEEE Eng Med Biol Mag. 2001;20(5):72–9]. We are now conducting the first prospective study in newborn babies with risk factors for infantile spasms.

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