3. The effect of environmental enrichment on GBL-induced Infantile Spasm-like seizures in Ts65Dn mice

Infantile spasms (IS) is the most common and severe form of epilepsy that occurs in infants between four and twelve months of age. Symptoms of IS include sporadic flexion and/or extension in all limbs and torso, multifocal spike discharges and manifestation of cognitive and psychomotor impairments later on in development. A strong correlation between Down Syndrome (DS) and IS was reported in recent research. It has also been shown that environmental enrichment was able to reduce the severity of atypical absence epilepsy, which is observed after IS in some patients, in a rat model.

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