Measuring neuropathy in obese populations: Challenge accepted. Reply to “Diagnostic accuracy of neuropathy tests in obese population remains elusive”

Our manuscript "Better diagnostic accuracy of neuropathy in obesity: A new challenge for neurologists" was performed to address a current gap in our understanding of measuring neuropathy in obese populations (Callaghan et al., 2018). We determined the diagnostic characteristics of several neuropathy measures for three of the most common types of peripheral neuropathy, namely distal symmetric polyneuropathy (DSP), small fiber neuropathy (SFN), and cardiac autonomic neuropathy (CAN). We studied morbidly obese patients prior to them participating in a weight management program and defined neuropathy using the Toronto consensus definition of neuropathy, which requires only clinical information (Dyck et al., 2011).

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