Electrogastrography, Near-infrared Spectroscopy and Acoustics to Measure Gastrointestinal Development in Preterm Babies

ABSTRACTObjectives:To obtain objective measures indicative of gastrointestinal maturity using three non-invasive technologies.Methods:Electrogastrography (EGG), abdominal near-infrared spectroscopy (NIRS), and bowel sound/acoustics (AC) monitoring were used simultaneously to obtain physiologic measures of the gastrointestinal system of 18 preterm and 5 term neonates who were tolerating enteral feedings.Measures of EGG slow wave voltage (EGG dominant power) and AC signal amplitude (AC dominant power) were obtained after spectral density analysis. Mean abdominal regional saturations (A-rSO2) were obtained directly from NIRS. The relationship of these three measures with postmenstrual age (PMA) was assessed.Results:The results of the three methods differed depending on whether the measurements were pre-prandial or post-prandial. Post-prandial EGG dominant power increases with PMA (r = 0.67, p = 0.003), both pre- and post-prandial abdominal NIRS mean regional saturation increase with PMA (r = 0.73, p 

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