Cancer transcriptome profiling at the juncture of clinical translation

Cancer transcriptome profiling at the juncture of clinical translation

Cancer transcriptome profiling at the juncture of clinical translation, Published online: 27 December 2017; doi:10.1038/nrg.2017.96

Although cancer genome sequencing is becoming routine in cancer research, cancer transcriptome profiling through methods such as RNA sequencing (RNA-seq) provides information not only on mutations but also on their functional cellular consequences. This Review discusses how technical and analytical advances in cancer transcriptomics have provided various clinically valuable insights into gene expression signatures, driver gene prioritization, cancer microenvironments, immuno-oncology and prognostic biomarkers.

from Genetics via xlomafota13 on Inoreader http://ift.tt/2BVY5Zc
via IFTTT