Correlations between MUNIX and adapted multiple point stimulation MUNE methods

Publication date: February 2018
Source:Clinical Neurophysiology, Volume 129, Issue 2
Author(s): Karim Benmouna, Christophe Milants, François Charles Wang
ObjectiveThe aim of this study was to evaluate how the motor unit number index (MUNIX) is related to the adapted multiple point stimulation (AMPS) technique.MethodsMUNIX and AMPS technique were prospectively performed on thenar muscles in 20 consecutive patients referred to our neurophysiological laboratory with the clinical diagnosis of a possible motoneurone disorder (MND). The clinical and paraclinical assessment confirmed the diagnosis of MND in 13 out of 20 patients, amyotrophic lateral sclerosis (ALS) in 9 (with MND group). In the other 7 patients, there were neither evidence of MND, nor of any peripheral nervous system disease (without MND group).ResultsAMPS and MUNIX data were significantly (p < 0.001) lower in patients with MND than in patients without MND. There was a strong significant positive linear correlation between AMPS and MUNIX values (n = 20; R = 0.83; p < 0.01).ConclusionBoth MUNIX and AMPS methods could serve as a reliable marker to document the motor unit loss.SignificanceThe present paper constitutes one more clue of MUNIX reliability.



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